This year, we once again had a very competitive number of proposals submitted for funding from the Reback Family gift supporting research targeting the development of new therapies for hypoxic brain injury. Three projects were selected including studies by two young investigators. Jeremy Hermann, MD, a fellow in pediatric critical care medicine is studying novel cold shock proteins as potential adjuncts to therapeutic hypothermia in the treatment of hypoxic brain injury in the developing brain. Jessica Jarvis, PhD is a T32 fellow in Physical Medicine and Rehabilitation who will be examining the effect of the use of music therapy in critically ill infants and children with hypoxic-ischemic encephalopathy, and finally, Amy Wagner, MD will use a preclinical model of hypoxic brain injury from cardiac arrest to define mechanism-based optimization of pharmacological approaches to rehabilitation
Jeremy Herrmann, MD
Young Investigator Award – $20,000/one year
Establishing the Rice-Vanucci Model of Neonatal Hypoxic Ischemic Encephalopathy in Post-Natal-Day 10 Mice and Initial Exploration of the Role of RNA Binding Motif (RBM)-3 in Hypothermic Neuroprotection
Jessica Jarvis, PhD
Young Investigator Award – $20,000/one year
Feasibility of a Family-Centered Music Therapy Intervention During Pediatric Neurocritical Care
Amy Wagner, MD
Faculty Research Initiative Award – $20,000/one year
Mechanistic pharmacological studies of striato-pallidal-thalamic integrity after cardiac arrest induced hypoxic ischemic brain injury