University of Pittsburgh    |    School of Medicine

Journal Club
Journal Club

An integral component of the collaborative research and educational environment of the Safar Center is the Neurointensive Critical Care and Resuscitation Research Journal Club

The Safar Center for Resuscitation Research brings together many different departments and disciplines within the University of Pittsburgh School Of Medicine, the Children’s Hospital of Pittsburgh, and beyond. An integral component of the collaborative research and educational environment of the Safar Center is the Neurointensive Critical Care and Resuscitation Research Journal Club. The Journal Club is a casual space where students, trainees, and faculty of all levels meet to discuss the latest articles in the field of neurocritical care, neuroscience, neurotrauma, and resuscitation. The Journal Club meets every Friday.

2019
Date Presenters Article
##/##/2019 TBD TBD
2018
Date Presenters Article
9/29/18 Alcamo Association Between Time to Defibrillation and Survival in Pediatric In-Hospital Cardiac Arrest With a First Documented Shockable Rhythm
9/21/18 Hook Enriched Environment Elicits Proangiogenic Mechanisms After Focal Cerebral Ischemia
9/14/18 Alcamo A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest
9/7/18 Craine Effects of Mild Blast Traumatic Brain Injury on Cerebral Vascular, Histopathological, and Behavioral Outcomes in Rats
8/31/18 Wolf Induction of a Transmissible Tau Pathology by Traumatic Brain Injury
8/24/18 Wolf Validation of ICP Derived Cerebrovascular Indices Against the Lower Limit of Autoregulation, Part II: Experimental Model  of Arterial Hypotension
Time Spent with Impaired Autoregulation is Linked with Outcome in Severe Infant/Paediatric Traumatic Brian Injury
8/3/18 Alcamo Osmotic Shifts, Cerebral Edema, and Neurological Deterioration in Severe Hepatic Encephalopathy
7/27/18 Treble-Barna Longitudinal Developmental Outcomes After Traumatic Brain Injury in Young Children: Are Infants More Vulnerable Than Toddlers?
7/20/18 Iouchmanov Magnesium Administration After Experimental Traumatic Brain Injury Improves Decision-Making Skills
7/6/18 Cheng Juvenile Traumatic Brain Injury Results in Cognitive Deficits Associated with Impaired Endoplasmic Reticulum Stress and Early Tauopathy
6/22/18 Edinboro Repeat Mild Traumatic Brain Injury in Adolescent Rats Increases Subsequent 
5/25/18 Alcamo Association of Cerebrospinal Fluid Biomarkers of Central Nervious System Injury with Neurocognitive and Brain Imaging Outcomes in Children Reveiving Chemotherapy for Acute Lymphoblastic Leukimia.
5/18/18 Crisamore Dopaminergic Abnormalities Following Traumatic Brain Injury
5/11/18 Wolf Cilia-Based Flow Network in the Brain Ventricles
5/4/18 Radabaugh Environmental Enrichment Stimulates Immune Cell Secretion of Exosomes that Promote CNS Myelination and May regulate Inflammation
4/27/18 Treble-Barna Analysis of DNA Methylation in Young People: Limited Evidence for an Association Between Victimization Stress and Epigenetic Variation in Blood
4/13/18 Nichols Vagus Nerve Stimulation Delivered with Motor Training Enhances Recovery of Function after Traumatic Brain Injury
4/6/18 Wallisch Aquaporin 4 Blockade Improves Survival of Mirine Heart Allografts Subject to Prolonged Cold Ischemia
3/30/18 Alcamo Bacterial Dissemination to the Brain in Sepsis
3/23/18 Craine Post-Injury Administration of Galantamine Reduces Traumatic Brain Injury Pathology and Improves Outcome
3/16/18 Kochanek Ethics in Research Journal Club: Mentoring
Myths and Means of Mentoring
Collaboration & Mentoring
A New Approach to Mentoring for Research Careers: the National Research Mentoring Network
3/9/18 Alcamo Analysis of Magnetic Resonance Imaging Findings of Children with Neurologic Complications after Liver Transplantation
Clinical Utility of Computed Tomography and Megnetic Resonance Imaging for Diagnosis of Posterior Reversible Encephalopathy Syndrome after Stem Cell Transplantation in Children and Adolescents
3/2/18 Kochanek Balanced Crystalloids Versus Saline in Critically Ill Adults
Balanced Crystalloids versus Saline in Noncriticallly Ill Adults
2/23/18 Treble-Barna A Review of the Neuro and Inflammatory Responses in Post Concussion Systems: Introduction of the “Post-Inflammatory Brain Syndrome” PIBS
2/16/18 Alcamo Neurological Complications Following Pediatric Liver Transplant
Early and Late Neurological Complications of Liver Transplantation in Pediatric Patients
2/9/18 Kochanek Ethics in Research Journal Club: Reproducibility, Retraction, and Fraud
Raise Standards for Preclinical Cancer Research
Six Red Flags for Suspect Work
The Economics of Reproducibility in Preclinical Research
Retracting Bad Science Doesn’t Make it Disappear
NIH Section Chief with 19 Retractions is No Longer Running Lab
The Retraction Watch Leaderboard
How Many Scientists Fabricate and Falsify Research? A Systematic Review and Meta-Analysis of Survey Data
Fraud and Misconduct in Clinical Research: A Concern
2/2/18 Wolf Subarachniod Hemmorrhage Severely Impairs Brain Parenchymal Cerebrospinal Fluid Circulation in Nonhuman Primate          
The Glymphatic System in Central Nervous System Health and Disease: Past, Present, and Future
1/26/18 Li Mild Hypothermia Preserves Cerebral Cortex Microcirculation After Resuscitation in a Rat Model of Ca
1/19/18 O’Neil Stress Primes Microglial Polarization After Global Ischemia: Therapeutic Potential of Progesterone
2017
Date Presenters Title
12/15/7 Patel Cold Water Swimming Pretreatment Reduces Cognitive Deficits in a Rat Model of Traumatic Brain Injury
12/8/17 Carlson Activation of PERK Elicits Memory Impairment through Inactivation of CREB and Downregulation of PSD95 After Traumatic Brain Injury
12/1/17 Kutash Frontal Traumatic Brain Injury Increases Impulsive Decision Making in Rats: A Potential Role for the Inflammatory Cytokine Interleukin
11/10/17 Even Brain Oxygen Optimization in Severe Traumatic  Brain Injury Phase-II: A Phase II Randomized Trial
11/10/17 Wolf Perivascular AQP4 Dysregulation in the Hippocampal CA1 Area After Traumatic Brain Injury is Alleviated by Adenosine A24 Receptor Inactivation
11/3/17 Crisamore, Tang, Li Neuron-Specific Enolase Predicts Poor Outcome after Cardiac Arrest and Targeted Temperature Management: A Multicenter Study on 1,053 Patients
Protein S100 as Outcome Predictor after Out-of-Hospital Cardiac Arrest and Targeted Temperature Management at 33
10/27/17 Wallisch Hypertonic Saline Infustion Supresses Apoptosis of Hippocampal Cells in a Rat Model Cardiopulmonary Resuscitation
10/20/17 Hossian Human and Nonhuman primate Meninges Harbor Lymphatic Vessels that can be Visulaized Noninvasively by MRI
10/13/17 Hagos Neutrophil Polarization by IL-27 as a Therapeutic Target for Intracerebral Hemorrhage
10/6/17 Alcamo Immunosupressive Treatment Alters Secretion of Ileal Antimicrobial Peptides and Gut Microbiota and Favors Subsequent Colonization by Uropathogenic Escherichia coli
9/22/17 Madurski Low Circulating Acute Brain-Derived Neurotrophic Factor Levels Are Associated With Poor Long-Term Fucntional Outcome After Ischemic Stroke
9/15/17 Wolf Individualizing Thresholds of Cerebral Perfusion Pressure Using Estimated Limits of Autoregulation
9/08/17 de le Tremblaye Manipulating Cognitive Reserve: pre-Injury Evironmental Conditions Influence the Severity of Concussion Symptomology, gene expression, and Response to Melatonin Treatment Treatment in Rats
8/25/17 Wolf Cerebral Perfusion Pressure Insults and Associations with Outcome in Adult Traumatic Brain Injury
8/18/17 O’Neal Multivariate Connectome-based Symptom Mapping in Post-Stroke Patients: Network Supporting Language and Speech
8/11/17 Atterbury Endothelial TLR4 and the Microbiome Drive Cerebral Cavernous Malformations
8/4/17 O’Neil Enhanced Astrocytic D-Serine Underlies Synaptic Damage After Traumatic Brain Injury
7/28/17 Hussian, Carlson Regulation of Mitochondrial Function and Glutamergic System are the Target of Guanosine Effect in Traumatic Brain Injury
Homing of Cultured Edothelial Progenitor Cells and Their Effect on Traumatic Brain Injury in Rat Model
7/14/17 Treble-Barna Post-Traumatic Stress Disorder
6/23/17 Jackson RTN3 is a Novel Cold-Induced Protein and Mediates Neuroprotective Effects of RBM3
6/2/17 Morrison Dopamine Release in the Nucleaus Accumbens is Altered Following Traumatic Brain Injury
5/12/17 Cheng, Wallisch Environmental Enrichment Mitigates Deficits after Repeated Mild TBI
Effects of Aquaporin 4 Knockdown on Brain Edema of the Uninjured Side After Traumatic Brain Injury in Rats
5/5/17 Li Rheological Effects of Drag-Reducing Polymers Improve Cerebral Blood Flow and Oxygenation After Traumatic Brain Injury in Rats
4/28/17 Bondi Effects of Low-Dose Milnacipran on Event-Related Potentials and Neuropsychological Tests in Persons with Traumatic Brain Injury: A Preliminary Study
4/21/17 Treble-Barna Associations of BDNF Genotype and Promoter Methylation with Acute and Long-Trem Stroke Outcomes in an East Asian Cohort
4/14/17 Carlson Cognitive Deficits Develop 1 Month After Diffuse Brain Injury and are Exaggerated by Microglia-associated Reactivity to Peripheral Immune Challenge
4/7/17 Radabaugh Cognitive Deficits Develop 1 Month After Diffuse Brain Injury and are Exaggerated by Microglia-associated Reactivity to Peripheral Immune Challenge
3/24/17 O’Neil Frontal Traumatic Brain Injury in Rats Causes Long-Lasting Impairments in Impulse Control That Are Differentially Sensitive to Pharmacotherapeutics and Associated with Chronic Neuroinflammation
3/17/17 Tremblaye Hypothalamic CRFR1 is Essential for HPA Axis Regulation Following Chronic Stress
3/10/17 Wolf Pathophysiologic Mechanisms of Cerebral Ischemia and Diffusion Hypoxia in Traumatic Brain Injury
2/24/17 Horvat Hypothermia for Neuroprotection in Convulsive Status Epilepticus
2/15/17 Treble-Barna Psychological Factors Associated with Delayed Symptom Resolution in Children with Concussion
2/10/17 Hagos, Iordova Pathological a-Synuclein Transmission Initiated by Binding Lymphocyte-Activation Gene 3
Cell Type Specificity of Neurovascular Coupling in Cerebral Cortex
2/3/17 Wallisch Therapeutic Hypothermia after In-Hospital
Cardiac Arrest in Children
2016
Date Presenters Title
12/16/16 Horvat, Treble-Barna Endothelial Activation and Blood-Brain Barrier Injury as Risk Factors for Delirium in Critical Ill Patients
Relationship of Childhood Adversity and Neighborhood Violence to a Proinflammitory Phenotype in Emerging Adult Afreican American Men: An Epigenetic Link
12/9/16 Wallisch The Ketamine Effect on ICP in Traumatic Brain Injury
Effectiveness of ketamine in decreasing intracranial pressure
in children with intracranial hypertension
12/2/16 Adams Astrocyte Scar Formation Aids Central Nervous System Axon Regeneration
11/18/16 Lamade RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4
11/4/16 Wolfe A New Look at Cerebrospinal Fluid Circulation
10/28/16 Horvat Special Ethics Journal Club:
Toward a New Era of Trust and Transparency in Clinical Trials
10/21/16  Tremble-Barna Adaptive Functioning Following Pediatric Traumatic Brain Injury:
Relationship to Executive Function and Processing Speed
10/14/16 Clark, Li Targeted Lipid Profiling Discovers Plasma Biomarkers of Acute Brain Injury
Thiamine as a Neuroprotective Agent after Cardiac Arrest
10/7/16 Horvat Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension
9/23/16 Adams Bayesian Methodology for the Design and Interpretation of Clinical Trials in Critical Care Medicine: A Primer for Clinicians
9/16/16 Pang, Fink Cornell Assessment of Pediatric Delirium: A Valid, Rapid, Observational Tool for Screening Delirium in the PICU
Cerebral Oximitry During Caridac Arrest: A Multicenter Study of Neurologic Outcomes and Survival
9/9/16 Lajud Avila, Wallisch Diffuse Traumatic Brain Injury Affects Chronic Corticosterone Function in the Rat
Acute Traumatic Coagulopathy Accompanying Isolated Traumatic Brain Injury is Associated with Worse Long-Term Functional and Cognitive Outcomes
9/02/16 de la Tremblaye, Cheng Palmitoyl Serine: An Endogenous Neuroprotective Endocannabinoid-Like Entity After Traumatic Brain Injury
High School Athletes With ADHD and Learning Difficulties Have a Greater Lifetime Concussion History
8/26/16 Lamade, Chao RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4
Transfer of Mitochondria from Astrocytes to Neurons after Stroke
8/19/16 Hagos A Peptide for Targeted, Systemic Delivery of Imaging and Therapeutic Compounds into Acute Brain Injuries
8/12/16 Horvat, Wolf Predicting Intracranial Pressure and Brain Tissue Oxygen Crises in Patients with Severe Traumatic Brain Injury
High Intracranial Pressure Induced Injury in the Healthy Rat Brain
8/3/16 Jha, Griffith One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
Cardiac Arrest Triggers Hippocampal Neuronal Death Through Autophagic and Apoptotic Pathways
7/21/16 Clark, Pang, Simon Special Topic Journal Club: The Gut–Brain Connection
Feeding the Brain and Nurturing the Mind: Linking Nutrition and the Gut Microbiota to Brain Development
Microbiota Dysbiosis Controls the Neuroinflammatory Response after Stroke
The Gut Microbiota Influences Blood-Brain Barrier Permiability in Mice
7/15/16 Horvat Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage 
7/1/16 Adams Clinical trial of blood-brain barrier disruption by pulsed ultrasound.
6/24/16 Kochanek Glyburide Inhibits the Cryopyrin/Nalp3 Inflammasome
6/17/16 Hossain Rapid Alteration of Protein Phosphorylation During Postmortem: Implication in the Study of Protein Phosphorylation
6/10/16 Wallisch, Li Intracranial Pressure During Pressure Control and Pressure-Regulated Volume Control Ventilation in Patients with Traumatic Brain Injury: A Randomized Crossover Trial
Drag-Reducing Polymer Enhances Microvascular Perfusion in the Traumatized Brain with Intracranial Hypertension
5/13/16  Radabough, Pang Use of Zinc as a Treatment for Traumatic Brain Injury in the Rat: Effects on Cognitive and Behavioral Outcomes
Blue Light Reduces Organ Injury from Ischemia and Reperfusion
5/6/16 Hagos Improvement of Neuroenergetics by Hypertonic Lactate Therapy in Patients with Traumatic Brain Injury Is Dependent on Baseline Cerebral Lactate/Pyruvate Ratio 
Cell-specific Modulation of Monocarboxylate Transporter Expression Contributes to the Metabolic Reprograming Taking Place Following Cerebral Ischemia
4/29/16 Horvat, Lamade Early Propranolol after Traumatic Brain Injury is Associated with Lower Mortality
Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprograming
4/22/16 Kochanek Impact of Glasgow Coma Scale Score and Pupil Parameters on Mortality Rate and Outcome in Pediatric and Adult Severe Traumatic Brain Injury: A Retrospective, Multicenter Cohort Study
4/15/16 Laporte Long-Term Effects of Enriched Environment on Neurofuncitonal Outcome and CNS Lesion Volume After Traumatic Brain Injury in Rats
4/8/16 Jackson, Carlson Special Soapbox Session Journal Club: Antibodies-Fact or Fiction?
Antibody Anarchy: A Call to Order
Blame it on the Antibodies
4/1/16 Dezfulian, Hagos Minor Changes in Core Temperature Arrest Influence Outcomes: An Experimental Study
Time Course and Diagnostic Accuracy of Glial and Neuronal Blood Biomarkers and UCH-L1 in a Large Cohort of Trauma Patients With and Without Mild Traumatic Brain Injury
3/25/16 Horvat Prevalence of Early Posttraumatic Seizures in
Children With Moderate to Severe Traumatic Brain
Injury Despite Levetiracetam Prophylaxis
3/11/16 De La Tramayene Perinatal Asphyxia Results in Altered Expression of the Hippocampal Acylethanolamide/ Endocannabinoid Signalling System Associated to Memory Impairments in Postweaned Rats
2/26/2016 Horvat, Pang Special Topic Journal Club: Research Parasites, or Research Symbionts? Data Sharing and the Open Science Movement.
Data Sharing
Sharing Clinical Trial Data: A Proposal from the International Committee of Medical Journal Editors
2/12/2016 Manole Special Topic Journal Club: Brain Monitoring After Cardiac Arrest
Estimated Cerebral Oxyhemoglobin as a Useful Indicator of Neuroprotection in Patients with Post-Cardiac Arrest Syndrome: A Prospective, Multicenter Observational Study.
Increase in Cerebral Oxygenation During Advanced Life Support in Out-of-Hospital Patients is Associated with Return of Spontaneous Circulation.
Determinants and Significance of Cerebral Oximetry after Cardiac
Arest: A Prospective Cohort Study.
1/29/16 Osier Sports-Related Concussion Results in Differential Expression of Nuclear Factor-κ Pathway Genes in Peripheral Blood During the Acute and Subacute Periods.
1/15/2016 Hagos  Cargo Delivery into the Brain by in vivo identified Transport Peptides.
1/8/2016 Adams Endoplasmic reticulum stress implicated in chronic traumatic encephalopathy.
Early results of a helmetless-tackling intervention to decrease head impacts in football players.
2015
Date Presenters Title
12/18/15 Li, Bondi Traumatic brain injury results in rapid pericyte loss followed by reactive pericytosis in the cerebral cortex.
Closed head injury in an age-related alzheimer mouse model leads to an altered neuroinflammatory response and persistent cognitive impairment.
12/9/15 Hagos Suboptimal dosing parameters as possible factors in the negative Phase III clinical trials of progesterone for TBI.
12/4/15 Wallisch Cerebrovascular Pressure Reactivity in Children with Traumatic Brain Injury.
11/20/15 Horvat, Radabough Erythropoietin in Traumatic Brain Injury (EPO-TBI): a Double-Blind Randomised Controlled Trial.
A Behavioral and Histological Comparison of Fluid Percussion Injury and Controlled Cortical Impact Injury to the Rat Sensormotor Cortex.
11/6/15 Pang Host microbiota constantly control maturation and function of microglia in the CNS.
10/30/15 Kowalski, Lamade Dezfulian Student Poster Presentations:
New left bundle branch block (LBBB) is poorly predictive of coronary occlusion after Out-of-Hospital Cardiac Arrest (OHCA)
Increased Injury with Asphyxial versus VF Cardiac Arrest in Rat Brain.
10/23/15 Wallisch Aquaporin-4 distribution in control and stressed astrocytes in culture and in the cerebrospinal fluid of patients with traumatic brain injuries.
10/16/15 Horvat Hypothermia for Intracranial Hypertension after Traumatic Brain Injury
9/25/15 Simon Pivotal role of cerebral interleukin-17–producing gdT cells in the delayed phase of ischemic brain injury.
10/2/2015 Laporte  Mean girls: Sex differences in the effects of mild traumatic brain injury on the social dynamics of juvenile rat play behavior.
9/23/2015 Horvat, Oh Pediatric Traumatic Brian Injury and Attention Deficit.
Antibody Against Early Driver of Neurodegeneration cis P-tau Blocks Brain Injury and Tauopathy.
9/18/2015 Carlson, Cheng Synaptogenesis in the Hippocampal CA1 Field Following Traumatic Brain Injury.
A Novel Preclinical Model of Moderate Primary Blast-Induced Traumatic Brain Injury
9/4/2015 Horvat, Pang Plasma Biomarkers of Brian Injury as Diagnostic Tools and Outcome Predictors after Extracorporeal Membrane Oxygenation
The Effect of Body Posture on Brain Glymphatic Transport.
8/28/2015 Osier Melatonin ameliorates brain injury induced by systemic lipopolysaccharide in neonatal rats
8/14/2015 Laporte Pre and post-injury environmental enrichment effects functional recovery following medial frontal cortical contusions injury in rats.
8/7/2015 Kline Glucose Administration after traumatic brain injury exerts some benefits and no adverse effects on behavioral and histological outcomes.
7/31/2015 Hagos Transporter-mediated L-glutamate elimination from cerebrospinal fluid: possible involvement of excitatory amino acid transporters expressed in ependymal cells and choroid plexus epithelial cells.
7/24/2015 Kenny Cellular Protection using Flt3 and PI3Ka Inhibitors Demonstrates Multiple Mechanisms of Oxidative Glutamate Toxicity.
7/17/2015 Dezfulian, Jacobs Asphyxia-activated Corticocardiac Signaling Accelerates onset of Cardiac Arrest
Dietary Therapy Mitigates Persistent Wake Deficits Caused by
Mild Traumatic Brain Injury
7/10/2015 Pugh, Fidous Recovery of Cerebral Blood Flow Following Sport-Related Concussion
 6/26/2015 Hagos Role of the blood-cerebrospinal fluid barrier transporter as a cerebral clearance system for prostaglandin E2 produced in the brain.
6/19/2015  Pang Correlated gene expression supports synchronous activity in brain networks.
6/12/2015 Kochanek Special Topic Journal Club: “Ethics in Research: Predatory Journals and Misrepresentation of Data”
The Dark Side of Publishing
Intraneuronal APP, Not Free Aβ Peptides in 3xTg-AD Mice: Implications for Tau versus Aβ-Mediated Alzheimer Neurodegeneration
Scientific Articles Accepted (Personal Checks, Too)
6/5/2015 Hagos Dimethyl fumarate attenuates cerebral edema formation by protecting the blood–brain barrier integrity.
5/29/2015 Yang Inhibition of 12/15-Lipoxygenase as Therapeutic Strategy to Treat Stroke
5/8/2015 Carlson Albumin induces excitatory synaptogenesis through astrocytic TGF-β/ALK5 signaling in a model of acquired epilepsy following blood–brain barrier dysfunction
5/1/2015  Fink, Mendelson  Therapeutic hypothermia after Out-of-Hospital Cardiac Arrest in Children
4/24/2015 Adams, Hagos Special Topic Journal Club: “Transporters”
Quantitative Investigation of the Brian-to-Cerebrospinal Fluid Unbound Drug Concentration Ratio under Steady-State Conditions in Rats Using a Pharmacokinetic Model and Scaling Factors for Active Efflux Transporters.
Selective Increase of Two ABC Drug Efflux Transporters at the Blood-Spinal Cord Barrier Suggests Induced Pharmacoresistance in ALS
Inhibiting Drug Efflux Transporters Improves Efficacy of ALS Therapeutics
4/17/2015 Madha, Horvat An overview of the diagnosis and treatment of TBI in blast injury.
Very Early Administration of Progesterone for Acute Traumatic Brain Injury.
4/9/2015 Kochanek Randomized Pilot Trial of Intensive Management of Blood Pressure of Volume Expansion in Subarachniod Hemorrhage (IMPROVES).
4/3/2015 Madha Cytoskeletal protein α–II spectrin degradation in the brain of repeated blast exposed mice.
3/27/2015 Garman Special Topic Journal Club: “Neuronal death or dark neuron artifact, which is it?” 
The Fate of Nissi-stained Dark Neurons Following Traumatic Brain Injury in Rats: Difference Between Neocortex and Hippocampus Regarding Survival Rate.
Pharmacologic Analysis of the Mechanism of Dark Neuron Production in Cerebral Cortex.
3/20/2015 Jackson, Jha Special Topic Journal Club: “Cell Signaling Advances in Hypothermia”
RBM3 Mediates Structural Plasticity and Protective Effects of Cooling in Neurogeneration.
Cold-Inducibble RNA-Binding Protein (CIRP) Triggers Inflammatory Responses in Hemorrhagic Shock and Sepsis.
3/6/2015  Fidan Clinical Correlates in an Experimental Model of Repetitive Mild Traumatic Injury
2/27/2015 Dezfulian, Elmer Special Topic Journal Club: “Post-Resuscitation Neuroprotective Therapies after Cardiac Arrest”
Remote Ischemic Pre- and Postconditioning Improve Postresuscitation Myocardial and Cerebral Function in a Rat Model of Cardiac Arrest and Resuscitation.
Cognitive Function in Survivors of Out-of-Hospital Cardiac Arrest After Target Temperature Management at 33ºC Versus 36ºC.
2/20/2015 Brockman, Adams The Glasgow Coma Scale at 40 Years: Standing the Test of Time
Neuroprotective Effect of Ceftriaxone in a Rat model of Traumatic Brain Injury
2/10/2015 Carlson, Clark Special Topic Journal Club: “Emphatic for the Glymphatic System”
Biomarkers of Traumatic Injury are Transported from Brain via the Glymphatic System
Impaired Glymphatic Perfusion after Strokes Revealed by Contrast-Enhanced MRI
2/6/2015 Simon, Li Impairment of Glymphatic Pathway Function Promotes Tau Pathology after Traumatic Brain Injury
Evolution of Neuronal and Astroglial Disruption in the Peri-Contusional Cortex of Mice Revealed By in Vivo Two-Photon Imaging
1/30/2015 Bondi, Failla Protein Carbonylation after Traumatic Brain Injury: Cell Specificity Regional Susceptibility, and Gender Differences
Enhanced Attention Capture by Emotional Stimuli in Mild Traumatic Brain Injury
1/16/2015 Kochanek Chronic Neuropathologies of Single Repetitive TBI: Substrates of Dementia
1/8/2015 Jha AQP4 Tag Single Nucleotide Polymorphisms in Patients with Traumatic Brain Injury
2014
Presenters Date Title
Madha, Jackson 12/19/2014 A clinical trial of progesterone for severe traumatic brain injury.
Preimplantation factor promotes neuroprotection by targeting microRNA let-7.
Hagos, Pang 12/5/2014 Population pharmacokinetics of unbound hydrocortisone in critically ill Neonates and infants with vasopressor-resistant hypotension.
Pro-inflammatory T-lymphocytes rapidly infiltrate into the brain and contribute to neuronal injury following cardiac arrest and cardiopulmonary resuscitation.
Browning 11/21/2014 What is wrong with the tenets underpinning current management of severe traumatic brain injury?
A conceptual approach to managing severe traumatic brain injury in a time of uncertainty.
Madha 11/14/2014 The Effect of Posttraumatic Hypothermia on Diffuse Axonal Injury Following Parasagittal Fluid Percussion Brain Injury in Rats.
Carlson 11/7/2014 Sleep Restriction Impairs Blood–Brain Barrier Function.
Hagos  10/31/2014 Traumatic brain injury causes selective, CD74-dependant peripheral lymphocyte activation that exacerbates neurodegeneration.
Madha 10/24/2014 In vivo leukocyte-mediated brain microcirculatory inflammation: a comparison of osmotherapies and progesterone in severe traumatic brain injury.
Pang 10/16/2014 Randomized controlled trial comparing cerebral perfusion pressure–targeted therapy versus intracranial pressure–targeted therapy for raised intracranial pressure due to acute CNS infections in children.
Hagos 9/26/2015 Differential roles of microglia and monocytes in the inflamed central nervous system.
Oana Bondi, Leary 9/5/2014 Administration of low dose methamphetamine 12 h after a severe traumatic brain injury prevents neurological dysfunction and cognitive impairment of rats.
MMP-9 inhibitor SB-3CT attenuates behavioral impairments and hippocampal loss after traumatic brain injury.
Osier, Pang 8/22/2014 The spectrum of neurobehavioral sequelae after repetitive mild traumatic brain injury: A novel mouse model of chronic traumatic encephalopathy.
Matrix metalloproteinase-2 and metalloproteinase-9 activities are associated with blood-brain barrier dysfunction in an animal model of severe sepsis.
Liput 8/15/2014 Effects of adenosine monophosphate on induction of therapeutichypothermia and neuronal damage after cardiopulmonaryresuscitation in rats.
Carlson, Hagos 8/8/2014 Intravenous Transplants of Human Adipose-Derived Stem Cell Protect the Brain for Traumatic Brain Injury-Induced Neurodegeneration and Motor and Cognitive Impairments: Cell Graft Biodistribution and Soluble Factors in Young and Aged Rats.
Nrf2 Upregulates ATP Binding Cassette Transporter Expression and Activity at the Blood-Brain and Blood-Spinal Cord Barriers.
Dezfulian, Cheng 7/25/2014 Capillary pericytes regulate cerebral blood flow health and disease.
Rodent model of direct blast injury.
Brockman, Lamade 7/18/2015 Blood component transfusion increases the risk of death in children with traumatic brain injury.
A mitochondrial pathway for biosynthesis of lipid meditaors.
Hagos, Oana Bondi 7/11/2014 Fumarates promote cytoprotection of central nervous system cells against oxidative stress via the nuclear factor (erythroid-derived 2)-like 2 pathway.
A semicircular controlled cortical impact produces long-term motor and cognitive dysfunction that correlates well with damage to both the sensorimotor cortex and hippocampus.
Barton, Simon 6/27/2014 Stress-dose hydrocortisone reduces critical illness-related corticosteroid insufficiency associated with severe traumatic brain injury in rats.
Recombinant human interleukin-1 receptor antagonist in severe traumatic brain injury: a phase II randomized control trial.
Failla 6/20/2014 White matter/gray matter contrast changes in chronic and diffuse traumatic brain injury.
Kochanek 6/13/2014 Heterogeneity affecting outcome from acute stroke therapy: Making reperfusion worse.
Cerebral ischemia and reperfusion: The pathophysiologie concept as a basis for clinical therapy.
Adam 6/6/2014 Gibenclamide reduces secondary brain damage after experimental traumatic brain injury.
Newmeyer  5/30/2014 Randomized Controlled Trial Comparing Cerebral Perfusion Pressure-Targeted Therapy Versus Intracranial Pressure-Targeted Therapy for Raised Intracranial Pressure due to Acute CNS Infections in Children.
Juengst, Kumar 5/23/2014 Comparison of several prognostic tools in traumatic brain injury including S100B.
Long-term survival after traumatic brain injury: A population-based analysis controlled for nonhead trauma.
Diamond  5/16/2014 Inflammasome proteins in cerebrospinal fluid of brain injured patients as biomarkers of functional outcome.
Ferguson  5/9/2014 Intracranial Pressure Monitoring in Children With Severe Traumatic Brain Injury.
Simon, Kim-Campbell  5/2/2015 Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-Red fluorescent protein knock-in mice.
Extra cellular lactate increase is predominantly nonischemic in patients with severe traumatic brain injury.
Leary, Ritter  4/25/2014 Neuroprotective efficacy of a proneurogenic compound after traumatic brain injury.
Epidemiology, severity classification and outcome of moderate and severe traumatic brain injury: a prospective multicenter study.
Faila, Harun 4/18/2014 Robust training attenuates TBI-induced deficits in reference and working memory on the radial 8-arm maze.
Dopamine protects neurons against glutamate-induced excitotoxicity.
Uray, Carlson 4/10/2014 Effect of prehospital induction of mild hypothermia on survival and neurological status among adults with cardiac arrest.
Astrocyte control of synaptic NMDA receptors contributes to the progressive development of temporal lobe epilepsy.
Ferguson, Dezfulian 4/4/2014 Increased intracranial pressure after diffuse traumatic brain injury exacerbates neuronal somatic membrane poration but not axonal injury: evidence for primary intracranial pressure-induced neuronal perturbation.
Circulation nitrite contributes to cardioprotection by remote ischemic preconditioning.
Ritter, Kumar 3/28/2014 Neuroimaging, behavioral, and psychological sequelea of repetitive combined blast/impact mild traumatic brain injury in Iraq and Afghanistan War veterans.
Inflammation and white matter degeneration persist for years after a single traumatic brain injury.
Pang, Failla 3/21/2014 Lipopolysaccharide-induced microglial activation neuroprotection against experimental brain injury is independent of hemotogenous TLR4.
Reversal of established traumatic brain injury-induced, anxiety-like behavior in rats after delayed, post-injury neuroimmune suppression.
Harun, Simon 3/14/2014 Activation of D1 dopamine receptors induces emergence from isoflurane general anesthesia.
Pyroptotic neuronal cell death mediated by the AIM2 inflammasome.
Coppler 3/7/2014 Adenosine, lidocaine, and MG2+  (ALMTM) increases survival and corrects coagulopathy after eight-minute asphyxia cardiac arrest in the rat.
Propofol impairs neurogenesis and neurologic recovery and increases mortality rate in adult rats after traumatic brain injury.
Ritter
Failla		 2/28/2014 Disrupted modular organization of resting-state cortical functional connectivity in U.S. military personnel following concussive ‘mild’ blast-related traumatic brain injury.
Environmental enrichment may protect against hippocampal atrophy in the chronic stages of traumatic brain injury.
Tehranian
Browning		 2/7/2014 Rehabilitation improves behavioral recovery and lessens cell death without affecting iron, ferritin, transferrin, or inflammation after intracerebral hemorrhage in rats.
Neuroprotective, neuroplastic, and neurobehavorial effects of daily treatment with levetiracetam in experimental traumatic brain injury.
Garman, Simon 1/31/2014 Diffusion tensor imaging reveals white matter injury in a rat model of repetitive blast-induced traumatic brain injury
Progressive neurodegeneration after experimental brain trauma: association with chronic microglial activation
Brockman  1/24/2014 Glibenclamide is superior to decompressive craniectomy in a rat model of malignant stroke.
Failla 1/17/2014 Alteration in BNDF and Its Receptors, Full-lenght and Truncated TrKB and P75NRT Following Penetrating Traumatic Brain Injury
2013
Date Presenters Title
12/20/2013 Leary, Coppler Primary blast traumatic brain injury in the rat: relating diffusion tensor imaging and behavior.
Targeted temperature management at 33̊C versus 36̊C after cardiac arrest.
12/13/2013 Kim-Campbell Nitric Oxide delivery during cardopulmonary bypass reduces postoperative morbidity in children–a randomized trial.
12/6/13 Brockman High-dose albumin treatment for acute ischaemic stroke
(ALIAS) part 2: a randomised, double-blind, phase 3,
placebo-controlled trial.
11/22/13  Simon, Pang Mitocondrial cardiolipin is required for Nlrp3 inflammasome activation.
Extracellular acidosis is a novel danger signal alerting innate immunity via the Nlrp3 inflammasone.
11/15/13 Hagos ABC transporters B1, C1, and G2 differentially regulate neuroregeneration in mice.
11/08/13 Simon Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states.
11/01/13 Carlson GABA progenitors grafted into the adult epileptic brain control seizures and abnormal behavior.
10/25/13 Bondi, Ferguson Repetitive concussive traumatic brain injury interacts with post-injury foot shock stress to worsen social and depression-like behaviors in mice.
Influences of developmental age on the resolution of diffuse traumatic intracranial hemorrhage and axonal injury.
10/18/13 Kline Late exercise reduces neroinflammation and cognitive dysfunction after traumatic brain injury.
10/11/13 Adams Amantadine improves cognitive outcome and increases neuronal survival after fluid percussion traumatic brain injury in rats.
10/4/13 Uray, Brockman Effects of moderate and deep hypothermia on RNA-bonding proteins RBM3 and CIRP expressions in murine hippocampal brain slides.
Balanced versus chloride-rich solutions for fluid resuscitation in brain injured patients: a randomized double-blind pilot.
9/27/13 Tehranian, Kim-Campbell Repeated mild closed head injury impairs short-term visuospatial memory and complex learning.
Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): randomized placebo-controlled trial.
9/20/13 Pang Early release of HMGB-1 from neurons after the onset of brain ischemia.
9/13/13 Ferguson, Trakas Intermittent versus continuous cerebrospinal fluid drainage management in adult severe traumatic brain injury: assessment of the intracranial pressure pattern.
Hyperoxemia and long-term outcome after traumatic brain  injury.
9/6/13 Mtaweh Half-molar sodium lactate infusion to prevent intracranial hypertensive episodes in severe traumatic brain injured patients: a randomized controlled trial.
8/30/13 Failla & Kumar, Osier A longitudinal study of major and minor depression following traumatic brain injury.
Protective effect of melatonin against head trauma-induced hippocampal damage and spatial memory deficits in immature rats.
8/23/13 Kim-Campbell, Brockman Vasopressin, steroids, and epinephrine and neurologically favorable survival after in-hospital cardiac arrest: a randomized trial.
Complications associated with prolonged hypertonic saline therapy in children with elevated intracranial pressure.
8/16/13 Netto Argon reduces neurohistopathological damage and preserves functional recovery after cardiac arrest in rats.
8/9/2013 Fidan Age-dependent microglial activation in immature brains after hypoxia-ischemia.
8/2/213 Miller-Ferguson, Carlson Comparison of hypothermia and normothermia after severe traumatic brain injury in children (Cool Kids): a phase 3. randomized trial.
Live imaging of astrocyte responses to acute injury selective juxtavascular proliferation.
7/24/13 Tehranian, Kim-Campbell Hypothermia and pharmacological regimens that prevent overexpression and overactivity of the extracellular calcium-sensing receptor protect neurons against traumatic brain injury.
Transfusion of red blood cells in patients with a prehospital Glasgow Coma Scale score of 8 or less and no evidence of shock is associated with worse outcomes.
7/12/2013 Bondi, Kim-Campbell The impact of enriched environment and transplantation of murine cortical embryonic stem cells on recovery from controlled cortical contusion injury.
Nonconvulsive seizures are common in children treated with extracorporeal cardiac life support.
6/28/13 Coppler, Uray Association between post-resuscitation partial pressure of arterial carbon dioxide and neurological outcome in patients with post-cardiac arrest syndrome.
Effect of time and day on prehospital care and outcomes after out-of-hospital cardiac arrest.
6/21/13 Ferguson,  Brockman Extracorporeal membrane oxygenation and cerebral blood flow velocity in children.
Microglial activation induced by brain trauma is suppressed by post-injury treatment with a PARP inhibitor.
6/14/13 Dezfulian Endogenous nitric oxide induces activation apoptosis signal-regulating kinase 1 via s-nitrosylation in rat hippocampus during cerebral ischemia-reperfusion.
6/7/13 Shein Timing of Intracranial Hypertension Following Severe Traumatic Brain Injury
5/31/13 Hoshitsuki Acute Minocycline Treatment Mitigates the Symptoms of Mild Blast-Induced Traumatic Brain Injury
5/24/13 Failla Resting-state functional magnetic resonance imaging activity and connectivity and cognitive outcome in traumatic brain injury.
Long-term declarative memory deficits in diffuse TBI: Correlations with cortical thickness, white matter integrity and hippocampal volume.
5/10/13 Browning, Anderson Decompressive Craniectomy in Children: Single-Center Series and Systematic Review.
Early Brain Injury Alters the Blood-Brain Barrier Phenotype in Parallel with β-Amyloid and Cognitive Changes in Adulthood.
5/3/13 Fink, Kochanek Noninvasive Quantification of Human Brain Antioxidant Concentrations after an Intravenous Bolus of Vitamin C.
Albimin Resuscitation for Traumatic Brain Injury: is Intracranial Hypertension the Cause of Increased Mortality?
4/26/13 Brockman, Mtewah Amelioration of Acute Sequelae of Blast Induced Mild Traumatic Brain Injury by N-Acetyl Cysteine: A Double-Blind, Placebo Controlled Study.
Magnesium for Aneurysmal Subarachnoid Haemorrhage (MASH-2): a Randomised Placebo-Controlled Trial.
4/19/13 Simon, Willyerd Cutting edge: Nitric oxide inhibits the NLRP3 inflammasome.     
2. Brain iron quantification in mild traumatic brain injury: a magnetic field correlation study. 
4/12/13 Bondi, Uray Vulnerability imposed by diet and brain trauma for anxiety-like phenotype: implications for post-traumatic stress disorders.
Increasing arterial oxygen partial pressure during cardiopulmonary resuscitation is associated with improved rates of hospital admission.
4/5/13 Ferguson, Shein A prospective study to evaluate the antipyretic effect of the combination of acetaminophen and ibuprofen in neurological ICU patients.
Early-stage microvascular alterations of a new model of controlled cortical traumatic brain injury: 3D morphological analysis using scanning electron miscroscopy and corrosion casting.
3/29/13 Cancelled  
3/22/13 Coppler, Dezfulian Long term outcomes in elderly survivors of in hospital cardiac arrest.
Neurovascular coupling varies with level of global cerebral ischemia in a rat model.
3/15/13 Cancelled  
3/8/13 Failla, Russell Detection of blast-related traumatic brain injury in U.S. military personnel.
The Brain Activity Map Project and the challenge of functional connectomics.
3/1/13 Garman, Simon Isoflurane-induced apoptosis of oligodendrocytes in the neonatal primate brain.
Inhaled nitric oxide reduces secondary brain damage after traumatic brain injury in mice.
2/22/13 Kochanek Special Topic Journal Club: Publication Ethics
Heterogeneity affecting outcome from acute stroke therapy : making reperfusion worse.
Cerebral ischemia and reperfusion: the pathophysiologic concept as a basis for clinical therapy.
Note from the Editor. Journal of Cerebral Blood Flow & Metabolism (2005) 25, 291.
2/15/13 Cancelled  
2/08/13 Willyerd, Brockman   Novel methods to predict increased intracranial pressure during intensive care and long-term neurologic outcome after traumatic brain injury: development and validation in a multicenter dataset.
A comparison of the effects of nicotinamide and progesterone on functional recovery of cognitive behavior following cortical contusion injury in the rat.
2/01/13 Garman, Jackson Repetitive Mild Traumatic Brain Injury Augments Tau Pathology and Glial Activation in Aged hTau Mice.
Extracellular Guanosine Regulates Extracellular Adenosine Levels.
Further Reading:  Dueling Nucleosides: Cross-regulation of Extracellular Adenosine by Guanosine Editorial Focus on “Extracellular Guanosine Regulates Extracellular Adenosine Levels”
1/25/13 Bondi, Shein Blast exposure induces post-traumatic stress in disorder-related traits in a rat model of mild traumatic brain injury.
Volatile anesthetics influence blood-brain barrier integrity modulation of tight junction protein expression in traumatic brain injury.
1/18/13 Anderson, Ferguson Pharmacokinetics of levetiracetam in Neonates with seizures.
Nonconvulsive seizures are common in critically ill children.
1/11/13 Monaco, Brockman The effect of enriched environment on the outcome of traumatic brain injury; a behavioral, proteomics, and histological study.
Transfusion of hemoglobin-based oxygen carriers in the carboxy state is beneficial during transient focal cerebral ischemia
1/4/13 Russell, Kochanek Default-Mode Network Disruption in Mild Traumatic Brain Injury.
The relationship between cerebrospinal fluid creatine kinase and morphologic changes in the brain after transient cardiac arrest.
2012
Date Presenters Title
12/21/12 Tehranian, Coppler Inhibition of Autophagy Contributes to Ischemic Postconditioning-Induced Neuroprotection against Focal Cerebral Ischemia in Rats.
Nationwide Improvements in Survival From Out-of-Hospital Cardiac Arrest in Japan.
12/14/12 Simon, Garman Neuron-Specific Enolase, but Not S100B or Myelin Basic Protein, Increases in Peripheral Blood Corresponding to Lesion Volume after Cortical Impact in Piglets.
Astrocytes Are an Early Target in Osmotic Demyelination Syndrome.
12/7/12 Uray, Shein Trends in Survival after In-Hospital Cardiac Arrest.
Hyperoxia, hypocapnia and hypercapnia as outcome factors after cardiac arrest in children.
11/30/12 Kim-Campbell, Carter Goal Directed Brain Tissue Oxygen Monitoring Versus Conventional Management in Traumatic Brain Injury: An Analysis of In Hospital Recovery.
Inflammation after Trauma: Microglial Activation and Traumatic Brain Injury.
11/16/12 Bondi, Mtaweh Concussive Brain Injury Enhances Fear Learning and Excitatory Processes in the Amygdala.
Continuous Electroencephalography Monitoring for Early Prediction of Neurological Outcome in Postanoxic Patients After Cardiac Arrest: A Prospective Cohort Study.
11/9/12 Cancelled  
11/2/12 Jackson PHLPP1 Gene Deletion Protects the Brain from Ischemic Injury
10/26/12 Folweiler, Simon Impact of inhibition of erythropoietin treatment-mediated neurogenisis in the dentate gyrus of the hippocampus on restoration of spatial learning after traumatic brain injury.
Effect of analgesics and sedatives on the occurrence of spreading depolarizations accompanying acute brain injury.
10/19/12 Shein, Kim-Campbell Hyperoxia is associated with increased mortality in patients treated with mild therapeutic hypothermia after sudden cardiac arrest.
Free-Radical Scavenger Edaravone Treatment Confers Neuroprotection Against Traumatic Brain Injury in Rats.
10/12/12 Russell, Kochanek Early attention impairment and recovery profiles after childhood traumatic brain injury.
Open-label Randomized trial of the safety and efficacy of a single dose conivaptan to raise serum sodium in patients with traumatic brain injury.
10/5/12 Carter The effect and severity on behavior: a phenotypic study of cognitive and emotional deficits after mild, moderate, and severe controlled cortical impact injury in mice.
9/28/12 Dezfulain, Harun Contribution of Ih to neuronal damage to the hippocampus after traumatic brain injury in rats.
A pilot study examining the severity and outcome of post-cardiac arrest syndrome: a comparative analysis of two geographically distinct hospitals.
9/21/12 Shein Monitoring and prediction of intracranial hypertension in pediatric traumatic brain injury: clinical factors and initial computed tomography.
9/14/12 Zou, Manole Local glutamate level dictates adenosine A2A receptor regulation of neuroinflammation and traumatic brain injury.
Pericytes in capillaries are contractile in vivo, but arterioles mediate functional hyperemia in the mouse brain.
9/7/12 Simon Early cerebral metabolic crisis after TBI influences outcome despite adequate hemodynamic resuscitation.
8/24/12 Russell, Brockman Brain signal variability  relates to stability of behavior after recovery from diffuse brain injury.
Early cerebral perfusion pressure augmentation with phenylenphrine after traumatic brain injury may be neuroprotective in a pediatric swine model.
8/10/12 Mtaweh Traumatic brain injury-induced cognative deficits are attenuated by delayed and chronic treatment with the 5-HT(1A)-receptor agonist buspirone.
8/3/12 Kim-Campbell, Shein Results of a Phase II Placebo-controlled randomized trial of minocycline in acute spinal cord injury.
Mild hyperthermia worsens the neuropathological damage associated with mild traumatic brain injury in rats.
7/27/12 Kline, Monaco Lidocaine attenuates cognative impairment after isoflurane anesthsesia in old rats.
Traumatic brain injury in young rats leads to progressive behavioral deficits coincident with altered brain tissues in adulthood.
7/13/12 Russell Placebo-controlled trial of amantadine for severe traumatic brain injury
7/6/12 Carter Excitotoxicity downregulates TrkB.FL signaling and upregulates the neuroprotective truncated TrkB receptors in cultutred hippocampal and striatal neurons.
6/8/12 Manole, Shein Attenuation of neonatal ischemic brain damage using a 20-HETE synthesis inhibitor.
Use of serum biomarkers to predict cerebral hypoxia after severe traumatic brain injury
6/1/12 Dezfulian, Russell A validated prediction tool for initial survivors of in-hospital cardiac arrest.
Factors influencing intracranial pressure monitoring guideline compliance and outcome after severe traumatic brain injury.
5/25/12 Harun, Shein Vasopressin rescue for in-pediatric intensive care unit cardiopulmonary arrest refractory to initial epinephrine dosing: a prospective feasibility pilot trial.
Levodopa treatment improves functional recovery  after experimental stroke
5/18/12 Donnelly, Ferguson CSF-biomarkers in Olympic boxing: diagnosis and effects of repetitive head trauma.
Dynamics of glial fibrillary acidic protein during traumatic brain injury in children.
5/11/12 Shein, Russell Occurrence and impact of intracranial pressure elevation during treatment of severe intraventricular hemorrhage.
Neurophysiological alterations during strategy-based verbal learning in traumatic brain injury.
5/14/12 Su, Alexander Salience network integrity predicts default mode network function after traumatic brain injury.
Comparison of induced hypertension, fluid bolus, and blood transfusion to augment cerebral oxygen delivery after subarachnoid hemorrhage
4/27/12 Brayer, Carter Neuroprotective and neurorestorative effects of thymosin β4 treatment initiated 6 hours after traumatic brain in rats.
Microarray-based gene expression analysis of an animal model for closed head injury.
4/13/12 Russell, Chin Does an early onset and continuous chain of rehabilitation improve the long-term functional outcome of patients with severe traumatic brain injury?
In vivo quantifications of global connectivity in the human corpus callosum.
4/6/12 Dezfulian, Au Prehospital epinephrine use and survival among patients with out-of–hospital cardiac arrest.
Dendrimer-mediated siRNA delivery knocks out Beclin 1 and potentiates NMDA-mediated toxicity in rat cortical neurons.
3/30/12 Brockman, Su Blood soluble drag-reducing polymers prevent lethality from hemorrhagic shock in acute animal experiments.
Diffusion tensor imaging of diffuse axonal injury in  a rat brain trauma model.
3/16/12 Drabek, Dezfulian Comparison of the Durations of Mild Therapeutic Hypothermia on Outcome After Cardiopulmonary Resuscitation in the Rat.
The difference in myocardial injuries and mitochondrial damages between asphyxial and ventricular fibrillation cardiac arrests.
3/2/12 Ferguson, Fink Severe traumatic brain injury in children elevates glial fibrillary acidic protein in cerebrospinal fluid and serum.
Serum Levels of Neuron-Specific UCHL1 Predict Brain Injury in a Canine Model of Hypothermic Circulatory Arrest.
2/24/12 Russell, Au Intellectual Ability 10 Years after Traumatic Brain Injury in Infancy and Childhood: What Predicts Outcome?
Frequency and Timing of Nonconvulsive Status Epilepticus in Comatose Post-Cardiac Arrest Subjects Treated with Hypothermia
2/10/12 Simon, Shein Insufficient Activation of Autophagy Allows Cellular Damage to Accumulate in Critically ill Patients.
Sodium nitroprusside-enhanced cardiopulmonary resuscitation improves resuscitation rates after prolonged untreated cardiac arrest in two porcine models
2/4/12 Russell, Kochanek Default-Mode Network Disruption in Mild Traumatic Brain Injury.
The relationship between cerebrospinal fluid creatine kinase and morphologic changes in the brain after transient cardiac arrest.
1/27/12 Simon, Shein Comparison Between Cerebral Tissue Oxygen Tension and Energy Metabolism in Experimental Subdural Hematoma.
Outcome prediction by motor and papillary responses in children treated with therapeutic hypothermia after cardiac arrest.
1/20/12 Dezfulian, Ferguson Requirement of argininosuccinate lyase for systemic nitric oxide production.
Intracranial Pressure Changes following Traumatic Brain Injury in Rats: Lack of Significant Change in the Absense of Mass Lesions or Hypoxia.
1/13/12 Mtaweh, Tehranian Early Enteral Nutrition and Clinical Outcomes of Severe Traumatic Brain Injury Patients in Acute Stage: A Multi-Center Cohort Study.
Minocyline Restores sAPPx Levels and Reduces the Late Histopathological Consequences of Traumatic Brain Injury in Mice.
1/6/12 Russell, Su What comes first? The dynamics of cerebral oxygenation and blood flow in response to changes in arterial pressure and intracranial pressure after head injury.
Early Microstructural and Metabolic Changes following Controlled Cortical Impact Injury in Rat: A Magnetic Resonance Imaging and Spectroscopy