University of Pittsburgh    |    School of Medicine

Publications
Publications

Safar Center Publications

Articles are listed in the order they are e-published. 

Latest Publications

  1. Acute and chronic effects of single dose memantine after controlled cortical impact injury in adult rats. Abrahamson EE, Poloyac SM, Dixon CE, Dekosky ST, Ikonomovic MD. Restor Neurol Neurosci. 2019 Jun 1. [Epub ahead of print]
  2. Important Outcomes for Parents of Critically Ill Children. Pasek TA, Burns C, Treble-Barna A, Ortiz-Aguayo R, Kochanek PM, Houtrow AJ, Beers SR, Fink EL. Crit Care Nurse. 2019 Jun;39(3):74-79.
  3. Factors Contributing to Fentanyl Pharmacokinetic Variability Among Diagnostically Diverse Critically Ill Children. Hagos FT, Horvat CM, Au AK, Conley YP, Li L, Poloyac SM, Kochanek PM, Clark RSB, Empey PE. Clin Pharmacokinet. 2019 Jun 6. doi: 10.1007/s40262-019-00773-1. [Epub ahead of print]
  4. Cooling via Trans-nasal High Flow Ambient Air: Does it Pass the Smell Test? Kochanek PM, Fink EL. Neurocrit Care. 2019 Jun;30(3):505-507.
  5. PICU-Based Rehabilitation and Outcomes Assessment: A Survey of Pediatric Critical Care Physicians. Treble-Barna A, Beers SR, Houtrow AJ, Ortiz-Aguayo R, Valenta C, Stanger M, Chrisman M, Orringer M, Smith CM, Pollon D, Duffett M, Choong K, Watson RS, Kochanek PM, Fink EL; PICU-Rehabilitation Study Group, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, and Prevalence of Acute critical Neurological disease in children: A Global Epidemiological Assessment (PANGEA) Investigators. Pediatr Crit Care Med. 2019 Jun;20(6):e274-e282.
  6. Experimental traumatic brain injury results in estrous cycle disruption, neurobehavioral deficits, and impaired GSK3β/β-catenin signaling in female rats. Fortress AM, Avcu P, Wagner AK, Dixon CE, Pang KCH. Exp Neurol. 2019 May;315:42-51.
  7. Redox (phospho)lipidomics of signaling in inflammation and programmed cell death. Tyurina YY, St Croix CM, Watkins SC, Watson AM, Epperly MW, Anthonymuthu TS, Kisin ER, Vlasova II, Krysko O, Krysko DV, Kapralov AA, Dar HH, Tyurin VA, Amoscato AA, Popova EN, Bolevich SB, Timashev PS, Kellum JA, Wenzel SE, Mallampalli RK, Greenberger JS, Bayir H, Shvedova AA, Kagan VE. J Leukoc Biol. 2019 May 9. [Epub ahead of print]
  8. Amelioration of Amyotrophic Lateral Sclerosis in SOD1G93A Mice by M2Microglia from Transplanted Marrow. Epperly MW, Fisher R, Rigatti L, Watkins S, Zhang X, Hou W, Shields D, Franicola D, Bayir H, Wang H, Thermozier S, Henderson A, Donnelly C, Wipf P, Greenberger JS. In Vivo. 2019 May-Jun;33(3):675-688.
  9. The role of prophylactic hypothermia on neurophysiological and functional measures in the setting of an iatrogenic spinal cord impact injury. Jorge A, Fish EJ, Dixon CE, Hamilton KD, Balzer J, Thirumala P. World Neurosurg. 2019 May 31. pii: S1878-8750(19)31506-2. [Epub ahead of print]
  10. Association of a Functional Polymorphism in the CHRFAM7A Gene with Inflammatory Response Mediators and Neuropathic Pain after Spinal Cord Injury. Huang W, Kabbani N, Brannan TK, Lin MK, Theiss MM, Hamilton JF, Ecklund JM, Conley YP, Vodovotz Y, Brienza D, Wagner AK, Robbins E, Sowa GA, Lipsky RH. J Neurotrauma. 2019 May 23. [Epub ahead of print]
2019
  1. Acute and chronic effects of single dose memantine after controlled cortical impact injury in adult rats. Abrahamson EE, Poloyac SM, Dixon CE, Dekosky ST, Ikonomovic MD. Restor Neurol Neurosci. 2019 Jun 1. [Epub ahead of print]
  2. Important Outcomes for Parents of Critically Ill Children. Pasek TA, Burns C, Treble-Barna A, Ortiz-Aguayo R, Kochanek PM, Houtrow AJ, Beers SR, Fink EL. Crit Care Nurse. 2019 Jun;39(3):74-79.
  3. Factors Contributing to Fentanyl Pharmacokinetic Variability Among Diagnostically Diverse Critically Ill Children. Hagos FT, Horvat CM, Au AK, Conley YP, Li L, Poloyac SM, Kochanek PM, Clark RSB, Empey PE. Clin Pharmacokinet. 2019 Jun 6. doi: 10.1007/s40262-019-00773-1. [Epub ahead of print]
  4. Cooling via Trans-nasal High Flow Ambient Air: Does it Pass the Smell Test? Kochanek PM, Fink EL. Neurocrit Care. 2019 Jun;30(3):505-507.
  5. PICU-Based Rehabilitation and Outcomes Assessment: A Survey of Pediatric Critical Care Physicians. Treble-Barna A, Beers SR, Houtrow AJ, Ortiz-Aguayo R, Valenta C, Stanger M, Chrisman M, Orringer M, Smith CM, Pollon D, Duffett M, Choong K, Watson RS, Kochanek PM, Fink EL; PICU-Rehabilitation Study Group, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, and Prevalence of Acute critical Neurological disease in children: A Global Epidemiological Assessment (PANGEA) Investigators. Pediatr Crit Care Med. 2019 Jun;20(6):e274-e282.
  6. Experimental traumatic brain injury results in estrous cycle disruption, neurobehavioral deficits, and impaired GSK3β/β-catenin signaling in female rats. Fortress AM, Avcu P, Wagner AK, Dixon CE, Pang KCH. Exp Neurol. 2019 May;315:42-51.
  7. Redox (phospho)lipidomics of signaling in inflammation and programmed cell death. Tyurina YY, St Croix CM, Watkins SC, Watson AM, Epperly MW, Anthonymuthu TS, Kisin ER, Vlasova II, Krysko O, Krysko DV, Kapralov AA, Dar HH, Tyurin VA, Amoscato AA, Popova EN, Bolevich SB, Timashev PS, Kellum JA, Wenzel SE, Mallampalli RK, Greenberger JS, Bayir H, Shvedova AA, Kagan VE. J Leukoc Biol. 2019 May 9. [Epub ahead of print] 
  8. Amelioration of Amyotrophic Lateral Sclerosis in SOD1G93A Mice by M2Microglia from Transplanted Marrow. Epperly MW, Fisher R, Rigatti L, Watkins S, Zhang X, Hou W, Shields D, Franicola D, Bayir H, Wang H, Thermozier S, Henderson A, Donnelly C, Wipf P, Greenberger JS. In Vivo. 2019 May-Jun;33(3):675-688. 
  9. The role of prophylactic hypothermia on neurophysiological and functional measures in the setting of an iatrogenic spinal cord impact injury. Jorge A, Fish EJ, Dixon CE, Hamilton KD, Balzer J, Thirumala P. World Neurosurg. 2019 May 31. pii: S1878-8750(19)31506-2. [Epub ahead of print]
  10. Association of a Functional Polymorphism in the CHRFAM7A Gene with Inflammatory Response Mediators and Neuropathic Pain after Spinal Cord Injury. Huang W, Kabbani N, Brannan TK, Lin MK, Theiss MM, Hamilton JF, Ecklund JM, Conley YP, Vodovotz Y, Brienza D, Wagner AK, Robbins E, Sowa GA, Lipsky RH. J Neurotrauma. 2019 May 23. [Epub ahead of print]
  11. Dietary Cellulose Supplementation Modulates the Immune Response in a Murine Endotoxemia Model. Di Caro V, Cummings JL, Alcamo AM, Piganelli JD, Clark RSB, Morowitz MJ, Aneja RK. Shock. 2019 Apr;51(4):526-534. 
  12. Lipidomics Detection of Brain Cardiolipins in Plasma Is Associated With Outcome After Cardiac Arrest. Anthonymuthu TS, Kenny EM, Lamade AM, Gidwani H, Krehel NM, Misse A, Gao X, Amoscato AA, Straub AC, Kagan VE, Dezfulian C, Bayır H. Crit Care Med. 2019 Apr;47(4):e292-e300. 
  13. New Developments for Pediatric Critical Care Medicine in 2019 and Beyond.Kochanek PM, Kudchadkar SR, Kissoon N. Pediatr Crit Care Med. 2019 Apr;20(4):311.
  14. PICU-Based Rehabilitation and Outcomes Assessment: A Survey of Pediatric Critical Care Physicians.Treble-Barna A, Beers SR, Houtrow AJ, Ortiz-Aguayo R, Valenta C, Stanger M, Chrisman M, Orringer M, Smith CM, Pollon D, Duffett M, Choong K, Watson RS, Kochanek PM, Fink EL; PICU-Rehabilitation Study Group, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, and Prevalence of Acute critical Neurological disease in children: A Global Epidemiological Assessment (PANGEA) Investigators. Pediatr Crit Care Med. 2019 Apr 3.  [Epub ahead of print]
  15. Variability in daily self-reported emotional symptoms and fatigue measured over eight weeks in community dwelling individuals with traumatic brain injury. Juengst SB, Terhorst L, Kew CL, Wagner AK. Brain Inj. 2019;33(5):567-573. doi: 10.1080/02699052.2019.1584333. Epub 2019 Mar 5.
  16. Secondary-Ion Mass Spectrometry Images Cardiolipins and Phosphatidylethanolamines at the Subcellular Level. Tian H, Sparvero LJ, Blenkinsopp P, Amoscato AA, Watkins SC, Bayır H, Kagan VE, Winograd N. Angew Chem Int Ed Engl. 2019 Mar 4;58(10):3156-3161.
  17. “Redox lipidomics technology: Looking for a needle in a haystack”.Tyurina YY, Tyurin VA, Anthonymuthu T, Amoscato AA, Sparvero LJ, Nesterova AM, Baynard ML, Sun W, He R, Khaitovich P, Vladimirov YA, Gabrilovich DI, Bayır H, Kagan VE. Chem Phys Lipids. 2019 Mar 27;221:93-107.
  18. Environmental enrichment and amantadine confer individual but nonadditive enhancements in motor and spatial learning after controlled cortical impact injury. Bleimeister IH, Wolff M, Lam TR, Brooks DM, Patel R, Cheng JP, Bondi CO, Kline AE. Brain Res. 2019 Mar 12. pii: S0006-8993(19)30139-8. [Epub ahead of print]
  19. Primum non nocere: a call for balance when reporting on CTE. Stewart W, Allinson K, Al-Sarraj S, Bachmeier C, Barlow K, Belli A, Burns MP, Carson A, Crawford F, Dams-O’Connor K, Diaz-Arrastia R, Dixon CE, Edlow BL, Ferguson S, Fischl B, Folkerth RD, Gentleman S, Giza CC, Grady MS, Helmy A, Herceg M, Holton JL, Howell D, Hutchinson PJ, Iacono D, Iglesias JE, Ikonomovic MD, Johnson VE, Keene CD, Kofler JK, Koliatsos VE, Lee EB, Levin H, Lifshitz J, Ling H, Loane DJ, Love S, Maas AI, Marklund N, Master CL, McElvenny DM, Meaney DF, Menon DK, Montine TJ, Mouzon B, Mufson EJ, Ojo JO, Prins M, Revesz T, Ritchie CW, Smith C, Sylvester R, Tang CY, Trojanowski JQ, Urankar K, Vink R, Wellington C, Wilde EA, Wilson L, Yeates K, Smith DH. Lancet Neurol. 2019 Mar;18(3):231-233.  Epub 2019 Feb 12. Erratum in: Lancet Neurol. 2019 Apr;18(4):e3.
  20. Ferroptosis Contributes to Neuronal Death and Functional Outcome After Traumatic Brain Injury. Kenny EM, Fidan E, Yang Q, Anthonymuthu TS, New LA, Meyer EA, Wang H, Kochanek PM, Dixon CE, Kagan VE, Bayir H. Crit Care Med. 2019 Mar;47(3):410-418. 
  21. Cooling via Trans-nasal High Flow Ambient Air: Does it Pass the Smell Test? Kochanek PM, Fink EL. Neurocrit Care. 2019 Mar 22. [Epub ahead of print] 
  22. Guidelines for the Management of Pediatric Severe Traumatic Brain Injury, Third Edition: Update of the Brain Trauma Foundation Guidelines, Executive Summary. Kochanek PM, Tasker RC, Carney N, Totten AM, Adelson PD, Selden NR, Davis-O’Reilly C, Hart EL, Bell MJ, Bratton SL, Grant GA, Kissoon N, Reuter-Rice KE, Vavilala MS, Wainwright MS. Pediatr Crit Care Med. 2019 Mar;20(3):280-289. 
  23. Management of Pediatric Severe Traumatic Brain Injury: 2019 Consensus and Guidelines-Based Algorithm for First and Second Tier Therapies. Kochanek PM, Tasker RC, Bell MJ, Adelson PD, Carney N, Vavilala MS, Selden NR, Bratton SL, Grant GA, Kissoon N, Reuter-Rice KE, Wainwright MS. Pediatr Crit Care Med. 2019 Mar;20(3):269-279. 
  24. Guidelines for the Management of Pediatric Severe Traumatic Brain Injury, Third Edition: Update of the Brain Trauma Foundation Guidelines. Kochanek PM, Tasker RC, Carney N, Totten AM, Adelson PD, Selden NR, Davis-O’Reilly C, Hart EL, Bell MJ, Bratton SL, Grant GA, Kissoon N, Reuter-Rice KE, Vavilala MS, Wainwright MS. Pediatr Crit Care Med. 2019 Mar;20(3S Suppl 1):S1-S82. 
  25. The Association of Very Early Serum levels of S100B, GFAP, UCH-L1, and SBDP with Outcome in ProTECT III. Frankel M, Fan L, Yeatts SD, Jeromin A, Vos PE, Wagner AK, Wolf BJ, Pauls Q, Lunney M, Merck LH, Hall CL, Palesch Y, Silbergleit R, David W. J Neurotrauma. 2019 Feb 22.  [Epub ahead of print]
  26. Comorbid Conditions Among Adults 50 Years and Older With Traumatic Brain Injury: Examining Associations With Demographics, Healthcare Utilization, Institutionalization, and 1-Year Outcomes. Kumar RG, Olsen J, Juengst SB, Dams-OʼConnor K, OʼNeil-Pirozzi TM, Hammond FM, Wagner AK. J Head Trauma Rehabil. 2019 Feb 27.  [Epub ahead of print]
  27. A Repeated Measures Pilot Comparison of Trajectories of Fluctuating Endogenous Hormones in Young Women with Traumatic Brain Injury, Healthy Controls.Niemeier JP, Perrin PB, Hurst BS, Foureau DM, Huynh TT, Evans SL, Silverman JE, Elise McClannahan M, Brusch BD, Newman M, Mougeot JL, Wagner AK. Behav Neurol. 2019 Feb 12;2019:7694503.
  28. Characterization of Differential Dynamics, Specificity, and Allostery of Lipoxygenase Family Members. Mikulska-Ruminska K, Shrivastava I, Krieger J, Zhang S, Li H, Bayır H, Wenzel SE, VanDemark AP, Kagan VE, Bahar I. J Chem Inf Model. 2019 Feb 28. doi: 10.1021/acs.jcim.9b00006. [Epub ahead of print]
  29. A New Vision for Therapeutic Hypothermia in the Era of Targeted Temperature Management: A Speculative Synthesis. Jackson TC, Kochanek PM. Ther Hypothermia Temp Manag. 2019 Mar;9(1):13-47. doi:
  30. Membrane transporters in traumatic brain injury: Pathological, pharmacotherapeutic, and developmental implications. Hagos FT, Adams SM, Poloyac SM, Kochanek PM, Horvat CM, Clark RSB, Empey PE.Exp Neurol. 2019 Feb 21. pii: S0014-4886(19)30024-X. doi: 10.1016/j.expneurol.2019.02.011. [Epub ahead of print].
  31. Downstream TRPM4 Polymorphisms Are Associated with Intracranial Hypertension and Statistically Interact with ABCC8 Polymorphisms in a Prospective Cohort of Severe Traumatic Brain Injury. Jha RM, Desai SM, Zusman BE, Koleck TA, Puccio AM, Okonkwo DO, Park SY, Shutter LA, Kochanek PM, Conley YP. J Neurotrauma. 2019 Feb 1.  [Epub ahead of print]
  32. 2′,3′-cGMP Exists In Vivo and Comprises a 2′,3′-cGMP-Guanosine Pathway. Jackson EK, Mi Z, Janesko-Feldman K, Jackson TC, Kochanek PM.Am J Physiol Regul Integr Comp Physiol. 2019 Feb 21. [Epub ahead of print]
  33. Paths to Successful Translation of New Therapies for Severe Traumatic Brain Injury in the Golden Age of Traumatic Brain Injury Research: A Pittsburgh Vision. Kochanek PM, Jackson TC, Jha RM, Clark RSB, Okonkwo DO, Bayır H, Poloyac SM, Wagner AK, Empey PE, Conley YP, Bell MJ, Kline AE, Bondi CO, Simon DW, Carlson SW, Puccio AM, Horvat CM, Au AK, Elmer J, Treble-Barna A, Ikonomovic MD, Shutter LA, Taylor DL, Stern AM, Graham SH, Kagan VE, Jackson EK, Wisniewski SR, Dixon CE. J Neurotrauma. 2019 Feb 1.  [Epub ahead of print]
  34. Targeted Temperature Management for Everyone: A Call for Tailoring Guidelines Based on Resource Availability. Alcamo AM, Fink EL. Pediatr Crit Care Med. 2019 Feb;20(2):206-207.
  35. Aripiprazole and environmental enrichment independently improve functional outcome after cortical impact injury in adult male rats, but their combination does not yield additional benefits. Besagar S, Radabaugh HL, Bleimeister IH, Meyer EA, Niesman PJ, Cheng JP, Bondi CO, Kline AE. Exp Neurol. 2019 Jan 16.[Epub ahead of print]
  36. Cardiolipin-dependent mitophagy guides outcome after traumatic brain injury. Chao H, Lin C, Zuo Q, Liu Y, Xiao M, Xu X, Li Z, Bao Z, Chen H, You Y, Kochanek PM, Yin H, Liu N, Kagan VE, Bayır H, Ji J. J Neurosci. 2019 Jan 9. [Epub ahead of print]
  37. Intermittent Administration of Haloperidol after Cortical Impact Injury Neither Impedes Spontaneous Recovery Nor Attenuates the Efficacy of Environmental Enrichment. Bao GC, Bleimeister IH, Zimmerman LA, Wellcome JL, Niesman PJ, Radabaugh HL, Bondi CO, Kline AE. J Neurotrauma. 2019 Jan 9. [Epub ahead of print]
  38. Chronic Treatment with Galantamine Rescues Reversal Learning in an Attentional Set-Shifting Test After Experimental Brain Trauma. Njoku I, Radabaugh HL, Nicholas MA, Kutash LA, O’Neil DA, Marshall IP, Cheng JP, Kline AE, Bondi CO. Exp Neurol. 2019 Jan 31. [Epub ahead of Print]
2018
  1. The elusive goal carbon dioxide target after cardiac arrest. Hirzallah MI, Dezfulian C. Resuscitation. 2018 Dec 15. pii: S0300-9572(18)31097-9. doi: 10.1016/j.resuscitation.2018.11.019. [Epub ahead of print]
  2. A Case of Lenticulostriate Stroke Due to Minor Closed Head Injury in a 2-Year-Old Child: Role of Mineralizing Angiopathy. Fidan E, Cummings DD, Manole MD. Pediatr Emerg Care. 2018 Dec;34(12):e233-e235.
  3. Empowerment of 15-lipoxygenase catalytic competence in selective oxidation of membrane ETE-PE to ferroptotic death signals, HpETE-PE. Anthonymuthu TS, Kenny EM, Shrivastava IH, Tyurina YY, Hier ZE, Ting HC, Dar H, Tyurin VA, Nesterova A, Amoscato AA, Mikulska-Ruminska K, Rosenbaum JC, Mao G, Jinming Z, Conrad M, Kellum JA, Wenzel SE, VanDemark AP, Bahar I, Kagan VE, Bayir H. J Am Chem Soc. 2018 Dec 7. [Epub ahead of print]
  4. Ferroptosis Contributes to Neuronal Death and Functional Outcome After Traumatic Brain Injury. Kenny EM, Fidan E, Yang Q, Anthonymuthu TS, New LA, Meyer EA, Wang H, Kochanek PM, Dixon CE, Kagan VE, Bayır H. Crit Care Med. 2018 Dec 6. [Epub ahead of print]
  5. Paths to successful translation of new therapies for severe TBI in the golden age of traumatic brain injury research: A Pittsburgh vision. Kochanek PM, Jackson TC, Jha R, Clark RSB, Okonkwo DO, Bayir H, Poloyac SM, Wagner AK M.D, Empey PE, Conley YP, Bell MJ, Kline AE, Bondi CO, Simon DW, Carlson SW, Puccio AM, Horvat CM, Au A, Elmer J, Treble-Barna A, Ikonomovic M, Shutter L, Taylor DL, Stern AM, Graham SH, Kagan VE, Jackson EK, Wisniewski SR, Dixon CE. J Neurotrauma. 2018 Dec 6.
  6. Metabolic and Structural Imaging at 7 Tesla After Repetitive Mild Traumatic Brain Injury in Immature Rats. Fidan E, Foley LM, New LA, Alexander H, Kochanek PM, Hitchens TK, Bayır H. ASN Neuro. 2018 Jan-Dec.
  7. November
  8. Intermittent administration of haloperidol after cortical impact injury neither impedes spontaneous recovery nor attenuates the efficacy of environmental enrichment. Bao G, Bleimeister I, Zimmerman L, Wellcome J, Niesman P, Radabaugh H, Bondi CO, Kline AE.J Neurotrauma. 2018 Nov 20. [Epub ahead of print]
  9. Factor structure of the Behavioral Assessment Screening Tool (BAST) in traumatic brain injury. Juengst SB, Terhorst L, Wagner AK. Disabil Rehabil. 2018 Nov 17:1-6. [Epub ahead of print]
  10. Dose-dependent neurorestorative effects of amantadine after cortical impact injury. Okigbo AA, Helkowski MS, Royes BJ, Bleimeister IH, Lam TR, Bao GC, Cheng JP, Bondi CO, Kline AE. Neurosci Lett. 2018 Nov 22;694:69-73.
  11. Extracorporeal Membrane Oxygenation and Hemolysis-Still a Challenge. Kim-Campbell N, Bayir H. Pediatr Crit Care Med. 2018 Nov;19(11):1089-1090.
  12. A Precision Medicine Approach to Cerebral Edema and Intracranial Hypertension after Severe Traumatic Brain Injury: Quo Vadis?Jha RM, Kochanek PM. Curr Neurol Neurosci Rep. 2018 Nov 7;18(12):105.
  13. Downstream TRPM4 Polymorphisms are associated with Intracranial Hypertension and Statistically Interact with ABCC8 Polymorphisms in a Prospective Cohort of Severe Traumatic Brain Injury. Jha RM, Desai SM, Zusman BE, Koleck TA, Puccio AM, Okonkwo DO, Park SY, Shutter L, Kochanek PM, Conley YP. J Neurotrauma. 2018 Nov 28.
  14. Infants Uniquely Express High Levels of RBM3 and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain. Jackson TC, Kotermanski SE, Kochanek PM. Dev Neurosci. 2018 Nov 6:1-12.
  15. Oxidative Stress Induces Release of 2′-AMP from Microglia. Jackson TC, Kotermanski SE, Kochanek PM, Jackson EK. Brain Res. 2018 Nov 2.
  16. Disentangling oxidation/hydrolysis reactions of brain mitochondrial cardiolipins in pathogenesis of traumatic injury. Chao H, Anthonymuthu TS, Kenny EM, Amoscato AA, Cole LK, Hatch GM, Ji J, Kagan VE, Bayır H. JCI Insight. 2018 Nov 2;3(21).
  17. October
  18. The aquaporin-4 inhibitor AER-271 blocks acute cerebral edema and improves early outcome in a pediatric model of asphyxial cardiac arrest. Wallisch JS, Janesko-Feldman K, Alexander H, Jha RM, Farr GW, McGuirk PR, Kline AE, Jackson TC, Pelletier MF, Clark RSB, Kochanek PM, Manole MD. Pediatr Res. 2018 Oct 26.[Epub]
  19. Quantitative and Qualitative Assessment of Glymphatic Flux Using Evans Blue Albumin.Wolf MS, Chen Y, Simon DW, Alexander H, Ross M, Gibson GA, Manole MD, Bayır H, Kochanek PM, Clark RSB.J Neurosci Methods. 2018 Oct 4. [Epub ahead of print]
  20. Pediatric Critical Care Medicine: Serving Our Missions While Maintaining Excellence. Kochanek PM, Kissoon N, Kudchadkar SR. Pediatr Crit Care Med. 2018 Oct;19(10):915-916.
  21. Quantitative and Qualitative Assessment of Glymphatic Flux Using Evans Blue Albumin. Wolf MS, Chen Y, Simon DW, Alexander H, Ross M, Gibson GA, Manole MD, Bayır H, Kochanek PM, Clark RSB. J Neurosci Methods. 2018 Oct 4. [Epub ahead of print]
  22. Duration of therapeutic hypothermia or targeted temperature management in pediatric cardiac arrest: Seeing through the ice. Kochanek PM, Jackson TC, Fink EL. Resuscitation. 2018 Sep 29. [Epub ahead of print]
  23. Early Recognition of Physical Abuse: Bridging the Gap between Knowledge and Practice. Berger RP, Lindberg DM. J Pediatr. 2018 Sep 26. pii: S0022-3476(18)31080-1. [Epub ahead of print]
  24. Iron catalysis of lipid peroxidation in ferroptosis: Regulated enzymatic or random free radical reaction? Stoyanovsky DA, Tyurina YY, Shrivastava I, Bahar I, Tyurin VA, Protchenko O, Jadhav S, Bolevich SB, Kozlov AV, Vladimirov YA, Shvedova AA, Philpott CC, Bayir H, Kagan VE. Free Radic Biol Med. 2018 Sep 12. [Epub ahead of print]
  25. Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium. Dar HH, Tyurina YY, Mikulska-Ruminska K, Shrivastava I, Ting HC, Tyurin VA, Krieger J, St Croix CM, Watkins S, Bayir E, Mao G, Ambruster C, Kapralov A, Wang H, Parsek MH, Anthonymuthu TS, Ogunsola AF, Flitter BA, Freedman CJ, Gaston JR, Holman TR, Pilewski JM, Greenberger JS, Mallampalli RK, Doi Y, Lee JS, Bahar I, Bomberger JM, Bayır H, Kagan VE. J Clin Invest. 2018 Sep 10. [Epub ahead of print]
  26. TBI Rehabilomics Research: Conceptualizing a humoral triad for designing effective rehabilitation interventions. Wagner AK, Kumar RG.Neuropharmacology. 2018 Sep 14.
  27. Tissue plasminogen activator promotes white matter integrity and functional recovery in a murine model of traumatic brain injury. Xia Y, Pu H, Leak RK, Shi Y, Mu H, Hu X, Lu Z, Foley LM, Hitchens TK, Dixon CE, Bennett MVL, Chen J. Proc Natl Acad Sci U S A. 2018 Sep 10. [Epub ahead of print]
  28. Arrest etiology among patients resuscitated from cardiac arrest. Chen N, Callaway CW, Guyette FX, Rittenberger JC, Doshi AA, Dezfulian C, Elmer J; Pittsburgh Post-Cardiac Arrest Service. Resuscitation. 2018 Sep;130:33-40
  29. Exploratory Application of Neuropharmacometabolomics in Severe Childhood Traumatic Brain Injury. Hagos FT, Empey PE, Wang P, Ma X, Poloyac SM, Bayir H, Kochanek PM, Bell MJ, Clark RSB. Crit Care Med. 2018 Sep;46(9):1471-1479.
  30. Dietary Cellulose Supplementation Modulates the Immune Response in a Murine Endotoxemia Model. Di Caro V, Cummings JL, Alcamo AM, Piganelli JD, Clark RSB, Morowitz MJ, Aneja RK. Shock. 2018 May 8. [Epub ahead of print]
  31. Synthesis and Evaluation of a Mitochondria-Targeting Poly(ADP-ribose) Polymerase-1 Inhibitor. Krainz T, Lamade AM, Du L, Maskrey TS, Calderon MJ, Watkins SC, Epperly MW, Greenberger JS, Bayır H, Wipf P, Clark RSB. ACS Chem Biol. 2018 Sep 14. [Epub ahead of print]
  32. A Big Loss for Our Field, But an Inspiration for Passion at the Bedside. Kochanek PM. Pediatr Crit Care Med. 2018 Sep;19(9):799.
  33. Pre-Clinical Testing of Therapies for Traumatic Brain Injury. DeWitt DS, Hawkins BE, Dixon CE, Kochanek PM, Armstead W, Bass CR, Bramlett HM, Buki A, Dietrich WD, Ferguson AR, Hall ED, Hayes RL, Hinds SR, LaPlaca MC, Long JB, Meaney DF, Mondello S, Noble-Haeusslein LJ, Poloyac SM, Prough DS, Robertson CS, Saatman KE, Shultz SR, Shear DA, Smith DH, Valadka AB, VandeVord P, Zhang L.J Neurotrauma. 2018 Dec 1;35(23):2737-2754. Epub 2018 Aug 30.
  34. Usefulness of Intravenous Sodium Nitrite During Resuscitation for the Treatment of Out-of-Hospital Cardiac Arrest. Kim F, Dezfulian C, Empey PE, Morrell M, Olsufka M, Scruggs S, Kudenchuk P, May S, Maynard C, Sayre MR, Nichol G.Am J Cardiol. 2018 Aug 15;122(4):554-559.
  35. Intracranial Pressure Trajectories: A Novel Approach to Informing Severe Traumatic Brain Injury Phenotypes.Jha RM, Elmer J, Zusman BE, Desai S, Puccio AM, Okonkwo DO, Park SY, Shutter LA, Wallisch JS, Conley YP, Kochanek PM.Crit Care Med. 2018 Aug 16.
  36. Multi-Center Pre-clinical Consortia to Enhance Translation of Therapies and Biomarkers for Traumatic Brain Injury: Operation Brain Trauma Therapy and Beyond. Kochanek PM, Dixon CE, Mondello S, Wang KKK, Lafrenaye A, Bramlett HM, Dietrich WD, Hayes RL, Shear DA, Gilsdorf JS, Catania M, Poloyac SM, Empey PE, Jackson TC, Povlishock JT. Front Neurol. 2018 Aug 7;9:640.
  37. Pathophysiology and treatment of cerebral edema in traumatic brain injury. Jha RM, Kochanek PM, Simard JM. Neuropharmacology. 2018 Aug 4. pii: S0028-3908(18)30471-4. [Epub ahead of print].
  38. Delayed and abbreviated environmental enrichment after brain trauma promotes motor and cognitive recovery that is not contingent on increased neurogenesis. Lajud N, Díaz-Chávez A, Radabaugh H, Cheng JP, Rojo-Soto G, Valdéz-Alarcón J, Bondi CO, Kline AE. J Neurotrauma. 2018 Jul 27. [Epub ahead of print]
  39. Employment stability in the first 5 years after moderate to severe traumatic brain injury. DiSanto D, Kumar R, Juengst SB, Hart T, O’Neil-Pirozzi TM, Zasler N, Novack TA, Dillahunt-Aspillaga C, Graham KM, Cotner BA, Rabinowitz A, Dikmen S, Niemeier J, Kesinger MR, Wagner AK. Arch Phys Med Rehabil. 2018 Jul 25. pii: S0003-9993(18)30461-1.  [Epub ahead of print]
  40. Lack of Benefit on Brain Edema, Blood-Brain Barrier Permeability or Cognitive Outcome in Global, Inducible HMGB1 Knockout Mice despite Tissue Sparing after Experimental Traumatic Brain Injury. Aneja RK, Alcamo A, Cummings JL, Vagni VA, Janesko-Feldman KL, Wang Q, Dixon CE, Billiar T, Kochanek PM. J Neurotrauma. 2018 Jul 26. [Epub ahead of print]
  41. Serum-based phospho-neurofilament-heavy protein as theranostic biomarker in three models of traumatic brain injury: an Operation Brain Trauma Therapy (OBTT) study. Yang Z, Zhu T, Mondello S, Akel M, Wong AT, Kothari IM, Lin F, Shear DA, Gilsdorf J, Leung LY, Bramlett HM, Dixon CE, Dietrich WD, Hayes RL, Povlishock J, Tortella FC, Kochanek PM, Wang KKW. J Neurotrauma. 2018 Jul 10. [Epub ahead of print]
  42. Aberrant cardiolipin metabolism is associated with cognitive deficiency and hippocampal alteration in tafazzin knockdown mice. Cole LK, Kim JH, Amoscato AA, Tyurina YY, Bayır H, Karimi B, Siddiqui TJ, Kagan VE, Hatch GM, Kauppinen TM. Biochim Biophys Acta. 2018 Jul 25. [Epub ahead of print]
  43. Aiming for the Target: Mitochondrial Drug Delivery in Traumatic Brain Injury. Lamade AM, Kenny EM, Anthonymuthu TS, Soysal E, Clark R, Kagan VE, Bayır H. Neuropharmacology. 2018 Jul 12. pii: S0028-3908(18)30375-7. Epub ahead of print] Review.
  44. Assessment of systemic administration of PEGylated IGF-1 in a mouse model of traumatic brain injury. Sama DM, Carlson SW, Joseph B, Saenger S, Metzger F, Saatman KE. Restor Neurol Neurosci. 2018;36(4):559-569.
  45. Craniectomy and Craniotomy in Traumatic Brain Injury: A Propensity-Matched Analysis of Long-Term Functional and Quality of Life Outcomes. Kelly ML, Shammassian B, Roach MJ, Thomas C, Wagner AK. World Neurosurg. 2018 Jul 23. pii: S1878-8750(18)31602-4. [Epub ahead of print]
  46. Spontaneous recovery after controlled cortical impact injury is not impeded by intermittent administration of the antipsychotic drug risperidone. Carlson LJ, Bao GC, Besagar S, Leary JB, Radabaugh HL, Bondi CO, Kline AE. Neurosci Lett. 2018 Jun 6;682:69-73. [Epub ahead of print]
  47. Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma.Hassannia B, Wiernicki B, Ingold I, Qu F, Van Herck S, Tyurina YY, Bayır H, Abhari BA, Angeli JPF, Choi SM, Meul E, Heyninck K, Declerck K, Chirumamilla CS, Lahtela-Kakkonen M, Van Camp G, Krysko DV, Ekert PG, Fulda S, De Geest BG, Conrad M, Kagan VE, Vanden Berghe W, Vandenabeele P, Vanden Berghe T. Clin Invest. 2018 Aug 1;128(8):3341-3355.  Epub 2018 Jun 25.
  48. Oxidized phospholipid signaling in traumatic brain injury. Anthonymuthu TS, Kenny EM, Lamade AM, Kagan VE, Bayır H. Free Radic Biol Med. 2018 Jun 30;124:493-503. [Epub ahead of print] Review.
  49. Systemic estrone production and injury induced sex hormone steroidogenesis after severe traumatic brain injury: a prognostic indicator of TBI-related mortality. Rakholia MV, Kumar RG, Oh BM, Ranganathan PR, Berga S, Kochanek PM, Wagner AK M.D. J Neurotrauma. 2018 Jun 27. [Epub ahead of print]
  50. Genetic re-engineering of polyunsaturated phospholipid profile of Saccharomyces cerevisiae identifies a novel role for Cld1 in mitigating the effects of cardiolipin peroxidation. Lou W, Ting HC, Reynolds CJ, Tyurina YY, Tyurin VA, Li Y, Ji J, Yu W, Liang Z, Stoyanovsky DA, Anthonymuthu TS, Frasso MA, Wipf P, Greenberger JS, Bayir H, Kagan VE, Greenberg ML.Biochim Biophys Acta. 2018 Jun 20. [Epub ahead of print]
  51. Preclinical Models of Traumatic Brain Injury: Emerging Role of Glutamate in the Pathophysiology of Depression. O’Neil DA, Nicholas MA, Lajud N, Kline AE, Bondi CO. Front Pharmacol. 2018 Jun 1;9:579.. eCollection 2018. Review.
  52. Novel therapies for combating chronic neuropathological sequelae of TBI. Ikonomovic MD, Abrahamson EE, Carlson SW, Graham SH, Dixon CE. Neuropharmacology. 2018 Jun 20. pii: S0028-3908(18)30310-1.. [Epub ahead of print] Review.
  53. Regulation of lipid peroxidation and ferroptosis in diverse species. Conrad M, Kagan VE, Bayir H, Pagnussat GC, Head B, Traber MG, Stockwell BR. Genes Dev. 2018 May 1;32(9-10):602-619. Review.
  54. Exploratory Application of Neuropharmacometabolomics in Severe Childhood Traumatic Brain Injury. Hagos FT, Empey PE, Wang P, Ma X, Poloyac SM, Bayır H, Kochanek PM, Bell MJ, Clark RSB. Crit Care Med. 2018 May 7. [Epub ahead of print]
  55. Neurostimulant prescribing patterns in children admitted to the ICU after traumatic brain injury. Morrison AM, Houtrow A, Zullo J, Kochanek PM, Vetterly C, Fink EL. J Neurotrauma. 2018 May 14. [Epub ahead of print]
  56. Career Development of Young Physician-Scientists in the Cardiovascular Sciences: Perspective and Advice From the Early Career Committee of the Cardiopulmonary, Critical Care, and Resuscitation Council of the American Heart Association. Agarwal S, Spiekerkoetter E, Austin ED, de Jesus Perez V, Dezfulian C, Maron BA, Ryan JJ, Starks MA, Yu PB, Bonnet S, Perman SM. Circ Res. 2018 May 11;122(10):1330-1333.
  57. How Bad Is It to Fail at Pushing Hard and Fast in Pediatric Cardiopulmonary Resuscitation? Dezfulian C, Fink EL. Pediatr Crit Care Med. 2018 May;19(5):495-496.
  58. Lithium improves dopamine neurotransmission and increases dopaminergic protein abundance in the striatum after traumatic brain injury. Carlson SW, Dixon CE. J Neurotrauma. 2018 Apr 27. [Epub ahead of print]
  59. The role of autophagy in acute brain injury: A state of flux? Wolf MS, Bayır H, Kochanek PM, Clark RSB. Neurobiol Dis. 2018 Apr 26. pii: S0969-9961(18)30133-5.
  60. Regionally clustered ABCC8 polymorphisms in a prospective cohort predict cerebral oedema and outcome in severe traumatic brain injury. Jha RM, Koleck TA, Puccio AM, Okonkwo DO, Park SY, Zusman BE, Clark RSB, Shutter LA, Wallisch JS, Empey PE, Kochanek PM, Conley YP. J Neurol Neurosurg Psychiatry. 2018 Apr 19. pii: jnnp-2017-317741. [Epub ahead of print]
  61. Probabilistic Matching of Deidentified Data From a Trauma Registry and a Traumatic Brain Injury Model System Center: A Follow-up Validation Study.Kumar RG, Wang Z, Kesinger MR, Newman M, Huynh TT, Niemeier JP, Sperry JL, Wagner AK. Am J Phys Med Rehabil. 2018 Apr;97(4):236-241.
  62. Traumatic Brain Injury and Infectious Encephalopathy in Children From Four Resource-Limited Settings in Africa.Fink EL, von Saint Andre-von Arnim A, Kumar R, Wilson PT, Bacha T, Aklilu AT, Teklemariam TL, Hooli S, Tuyisenge L, Otupiri E, Fabio A, Gianakas J, Kochanek PM, Angus DC, Tasker RC; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, PALISI Global Health Subgroup, and Prevalence of Acute Critical Neurological Disease in Children: A Global Epidemiological Assessment (PANGEA) Investigators.Pediatr Crit Care Med. 2018 Apr 16.  [Epub ahead of print]
  63. Glibenclamide produces region-dependent effects on cerebral edema in a combined injury model of traumatic brain injury and hemorrhagic shock in mice. Jha R, Molyneaux BJ, Jackson TC, Wallisch J, Park SY, Poloyac SM, Vagni VA, Janesko-Feldman KL, Hoshitsuki K, Minnigh MB, Kochanek PM. J Neurotrauma. 2018 Mar 8. doi: [Epub ahead of print]
  64. Operation Brain Trauma Therapy: 2016 Update. Kochanek PM, Bramlett HM, Dixon CE, Dietrich WD, Mondello S, Wang KW, Hayes RL, Lafrenaye A, Povlishock JT, Tortella FC, Poloyac SM, Empey P, Shear DA. Mil Med. March;183,(Sup 1):303–312
  65. Presenting Predictors and Temporal Trends of Treatment-Related Outcomes in Diabetic Ketoacidosis.Horvat CM, Ismail HM, Au AK, Garibaldi L, Siripong N, Kantawala S, Aneja RK, Hupp DS, Kochanek PM, Clark RSB. Pediatr Diabetes. 2018 Mar 24. doi: 10.1111/pedi.12663. [Epub ahead of print]
  66. Phenotyping Cardiac Arrest: Bench and Bedside Characterization of Brain and Heart Injury Based on Etiology. Uray T, Lamade A, Elmer J, Drabek T, Stezoski JP, Missé A, Janesko-Feldman K, Garman RH, Chen N, Kochanek PM, Dezfulian C; University of Pittsburgh Post-Cardiac Arrest Service. Crit Care Med. 2018 Mar 10.[Epub ahead of print]
  67. Environmental enrichment, alone or in combination with various pharmacotherapies, confers marked benefits after traumatic brain injury. de la Tremblaye PB, Cheng JP, Bondi CO, Kline AE.Neuropharmacology. 2018 Feb 27. [Epub ahead of print] Review.
  68. Brain-Specific Serum Biomarkers Predict Neurological Morbidity in Diagnostically Diverse Pediatric Intensive Care Unit Patients. Au AK, Bell MJ, Fink EL, Aneja RK, Kochanek PM, Clark RSB. Neurocrit Care. 2018 Feb;28(1):26-34.
  69. 24 vs. 72 Hours of Hypothermia for Pediatric Cardiac Arrest: A Pilot, Randomized Controlled Trial. Fink EL, Clark RSB, Berger RP, Fabio A, Angus DC, Watson RS, Gianakas JJ, Panigrahy A, Callaway CW, Bell MJ, Kochaneka PM. Resuscitation. 2018 Feb 14.
  70. Systemic administration of donepezil attenuates the efficacy of environmental enrichment on neurobehavioral outcome after experimental traumatic brain injury. Bondi CO, Yelleswarapu NK, Day-Cooney J, Memarzadeh K, Folweiler KA, Bou-Abboud CE, Leary JB, Cheng JP, Tehranian-DePasquale R, Kline AE. Restor Neurol Neurosci. 2018;36(1):45-57.
  71. Central Infusion of IGF-1 Increases Hippocampal Neurogenesis and Improves Neurobehavioral Function following Traumatic Brain Injury. Carlson SW, Saatman KE. J Neurotrauma. 2018 Feb 17.  [Epub ahead of print]
  72. A Special 50-Year Perspective on Our Field.Kochanek PM. Pediatr Crit Care Med. 2018 Feb 8.
  73. Development and content validity of the behavioral assessment screening tool (BASTβ). Juengst SB, Terhorst L, Dicianno BE, Niemeier JP, Wagner AK. Disabil Rehabil. 2018 Jan 5:1-7.
  74. Epidemiology of Comorbid Conditions Among Adults 50 Years and Older With Traumatic Brain Injury. Kumar RG, Juengst SB, Wang Z, Dams-OʼConnor K, Dikmen SS, OʼNeil-Pirozzi TM, Dahdah MN, Hammond FM, Felix ER, Arenth PM, Wagner AK. J Head Trauma Rehabil. 2018 Jan/Feb;33(1):15-24.
  75. Initiating Nutritional Support Before 72 Hours Is Associated With Favorable Outcome After Severe Traumatic Brain Injury in Children: A Secondary Analysis of a Randomized, Controlled Trial of Therapeutic Hypothermia. Meinert E, Bell MJ, Buttram S, Kochanek PM, Balasubramani GK, Wisniewski SR, Adelson PD; Pediatric Traumatic Brain Injury Consortium: Hypothermia Investigators. Pediatr Crit Care Med. 2018 Jan 24.
  76. The effects of post-traumatic depression on cognition, pain, fatigue, and headache after moderate-to-severe traumatic brain injury: a thematic review. Kumar RG, Gao S, Juengst SB, Wagner AK, Fabio A. Brain Inj. 2018 Jan 22:1-12. [Epub ahead of print]
2017
  1. BrainPhys® increases neurofilament levels in CNS cultures, and facilitates investigation of axonal damage after a mechanical stretch-injury in vitro. Jackson TC, Kotermanski SE, Jackson EK, Kochanek PM. Exp Neurol. 2018 Feb;300:232-246. doi: 10.1016/j.expneurol.2017.11.013. Epub 2017 Dec 1.
  2. Rehabilitative Success After Brain Trauma by Augmenting a Subtherapeutic Dose of Environmental Enrichment with Galantamine. de la Tremblaye PB, Wellcome JL, Wells de Witt B, Cheng JP, Skidmore ER, Bondi CO, Kline AE. Neurorehabil Neural Repair. 2017 Nov. [Epub Ahead of Print.]
  3. Cell-Free Plasma Hemoglobin and Male Gender Are Risk Factors for Acute Kidney Injury in Low Risk Children Undergoing Cardiopulmonary Bypass. Kim-Campbell N, Gretchen C, Callaway C, Felmet K, Kochanek PM, Maul T, Wearden P, Sharma M, Viegas M, Munoz R, Gladwin MT, Bayir H. Crit Care Med. 2017 Nov;45(11):e1123-e1130.
  4. Pre-clinical models in pediatric traumatic brain injury-challenges and lessons learned. Kochanek PM, Wallisch JS, Bayır H, Clark RSB. Childs Nerv Syst. 2017 Oct;33(10):1693-1701.
  5. Lateral fluid percussion injury impairs hippocampal synaptic soluble N-ethylmaleimide sensitive factor attachment protein receptor complex formation. Carlson SW, Henchir J, CE Dixon, Front. Neurol, Oct 2017;8:532.
  6. PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals.Wenzel SE, Tyurina YY, Zhao J, St Croix CM, Dar HH, Mao G, Tyurin VA, Anthonymuthu TS, Kapralov AA, Amoscato AA, Mikulska-Ruminska K, Shrivastava IH, Kenny EM, Yang Q, Rosenbaum JC, Sparvero LJ, Emlet DR, Wen X, Minami Y, Qu F, Watkins SC, Holman TR, VanDemark AP, Kellum JA, Bahar I, Bayır H, Kagan VE. Cell. 2017 Oct 19;171(3):628-641.e26. 
  7. The pharmacogenomics of severe traumatic brain injury. Adams SM, Conley YP, Wagner AK, Jha RM, Clark RS, Poloyac SM, Kochanek PM, Empey PE. Pharmacogenomics. 2017 Oct 4.  [Epub ahead of print]
  8. Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease. Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, Oyagi A, Pagnussat GC, Park J, Ran Q, Rosenfeld CS, Salnikow K, Tang D, Torti FM, Torti SV, Toyokuni S, Woerpel KA, Zhang DD. Cell. 2017 Oct 5;171(2):273-285. 
  9. Breaking Into the Top Ten. Kochanek PM, Kissoon N. Pediatr Crit Care Med. 2017 Oct;18(10):913-914. 
  10. The pharmacogenomics of severe traumatic brain injury. Adams SM, Conley YP, Wagner AK, Jha RM, Clark RS, Poloyac SM, Kochanek PM, Empey PE. Pharmacogenomics. 2017 Oct 4. 
  11. TBI Rehabilomics Research: an Exemplar of a Biomarker-Based Approach to Precision Care for Populations with Disability. Wagner AK. Curr Neurol Neurosci Rep. 2017 Sep 19;17(11):84. 
  12. ABCG2 c.421C>A Is Associated with Outcomes after Severe Traumatic Brain Injury.Adams SM, Conley YP, Ren D, Okonkwo DO, Puccio AM, Dixon CE, Clark RSB, Kochanek PM, Empey PE. J Neurotrauma. 2017 Sep 19. 
  13. Post-traumatic epilepsy associations with mental health outcomes in the first two years after moderate to severe TBI: A TBI Model Systems analysis. Juengst SB, Wagner AK, Ritter AC, Szaflarski JP, Walker WC, Zafonte RD, Brown AW, Hammond FM, Pugh MJ, Shea T, Krellman JW, Bushnik T, Arenth PM. Epilepsy Behav. 2017 Aug;73:240-246.
  14. Big Data Not Yet Big Enough to Determine the Influence of Intracranial Pressure Monitoring on Outcome in Children With Severe Traumatic Brain Injury. Horvat CM, Kochanek PM. JAMA Pediatr. 2017 Aug 28. [Epub ahead of print] 
  15. Cell-Free Plasma Hemoglobin and Male Gender Are Risk Factors for Acute Kidney Injury in Low Risk Children Undergoing Cardiopulmonary Bypass. Kim-Campbell N, Gretchen C, Callaway C, Felmet K, Kochanek PM, Maul T, Wearden P, Sharma M, Viegas M, Munoz R, Gladwin MT, Bayir H. Crit Care Med. 2017 Aug 31. [Epub ahead of print]
  16. Cardiac Arrest Secondary to Lightning Strike: Case Report and Review of the Literature.Rotariu EL, Manole MD.Pediatr Emerg Care. 2017 Aug 1. [Epub ahead of print]
  17. Oxidative lipidomics: applications in critical care.Anthonymuthu TS, Kim-Campbell N, Bayır H. Curr Opin Crit Care. 2017 Aug;23(4):251-256. 
  18. Whole-Transcriptome Microarray Analysis Reveals Regulation of Rab4 by RBM5 in Neurons. Jackson TC, Kotermanski SE, Kochanek PM. Neuroscience. 2017 Aug 14. pii: S0306-4522(17)30572-9. [Epub ahead of print]
  19. Therapeutic Hypothermia and Targeted Temperature Management With or Without the “Cold Stress” Response. Kochanek PM, Jackson TC. Ther Hypothermia Temp Manag. 2017 Aug 11 [Epub ahead of print] 

  20. The far-reaching scope of neuroinflammation after traumatic brain injury. Simon DW, McGeachy MJ, Bayır H, Clark RSB,Loane DJ, Kochanek PM. Nat Rev Neurol. 2017 Aug 4. 

  21. Minocycline Attenuates High Mobility Group Box 1 Translocation, Microglial Activation, and Thalamic Neurodegeneration after Traumatic Brain Injury in Postnatal Day 17 Rats.Simon DW, Aneja RK, Alexander H, Bell MJ, Bayır H, Kochanek PM, Clark RSB. J Neurotrauma. 2017 Aug 22.  [Epub ahead of print]
  22. Difficult Intubation and Ventilation in an Infant With Retropharyngeal Abscess With Mediastinal Extension.Bruno MA, Drabek T, Manole MD.Pediatr Emerg Care. 2017 Jul 17.  [Epub ahead of print]
  23. Primary Omental Torsion in a Pediatric Patient: Case Report and Review of the Literature. Madha ES, Kane TD, Manole MD. Pediatr Emerg Care. 2017 Jul 3. [Epub ahead of print]
  24. A Case of Lenticulostriate Stroke Due to Minor Closed Head Injury in a 2-Year-Old Child: Role of Mineralizing Angiopathy.Fidan E, Cummings DD, Manole MD. Pediatr Emerg Care. 2017 Jul 3. [Epub ahead of print]
  25. Comparable impediment of cognitive function in female and male rats subsequent to daily administration of haloperidol after traumatic brain injury. Free KE, Greene AM, Bondi CO, Lajud N, de la Tremblaye PB, Kline AE. Exp Neurol. 2017 Oct;296:62-68. Epub 2017 Jul 8.
  26. Interfacility Transport Shock Index Is Associated With Decreased Survival in Children.Jennings RM, Kuch BA, Felmet KA, Orr RA, Carcillo JA, Fink EL. Pediatr Emerg Care. 2017 Jul 11.  [Epub ahead of print]
  27. Mini Review of Controlled Cortical Impact: A Well-Suited Device for Concussion Research. Osier N, Dixon CE. Brain Sci. 2017 Jul 20;7(7). pii: E88.
  28. Phase I randomized clinical trial of N-acetylcysteine in combination with an adjuvant probenecid for treatment of severe traumatic brain injury in children. Clark RSB, Empey PE, Bayır H, Rosario BL, Poloyac SM, Kochanek PM, Nolin TD, Au AK, Horvat CM, Wisniewski SR, Bell MJ.PLoS One. 2017 Jul 7;12(7):e0180280. 
  29. Translational Stroke Research: Vision and Opportunities. Bosetti F, Koenig JI, Ayata C, Back SA, Becker K, Broderick JP, Carmichael ST, Cho S, Cipolla MJ, Corbett D, Corriveau RA, Cramer SC, Ferguson AR, Finklestein SP, Ford BD, Furie KL, Hemmen TM, Iadecola C, Jakeman LB, Janis S, Jauch EC, Johnston KC, Kochanek PM, Kohn H, Lo EH, Lyden PD, Mallard C, McCullough LD, McGavern LM, Meschia JF, Moy CS, Perez-Pinzon MA, Ramadan I, Savitz SI, Schwamm LH, Steinberg GK, Stenzel-Poore MP, Tymianski M, Warach S, Wechsler LR, Zhang JH, Koroshetz W. Stroke. 2017 Jul 27. [Epub ahead of print] 
  30. ABCG2 c.421C>A is Associated with Outcomes Following Severe Traumatic Brain Injury. Adams SM, Conley YP, Ren D, Okonkwo DO, Puccio A, Dixon CE, Clark RS, Kochanek PM, Empey PE. J Neurotrauma. 2017 Jul 26. [Epub ahead of print]
  31. Adding insight to injury: a new era in neurotrauma.Jha RM, Kochanek PM. Lancet Neurol. 2017 Aug;16(8):578-580. Epub 2017 Jul 11. 
  32. Translating biomarkers from research to clinical use in pediatric neurocritical care: focus on traumatic brain injury and cardiac arrest.Prout AJ, Wolf MS, Fink EL. Curr Opin Pediatr. 2017 Jun;29(3):272-279.
  33. Long-Term Deficits in Cortical Circuit Function after Asphyxial Cardiac Arrest and Resuscitation in Developing Rats.Middleton JW, Simons DJ, Simmons JW, Clark RSB, Kochanek PM, Shoykhet M.eNeuro. 2017 Jun 30;4(3). 
  34. Brain-Specific Serum Biomarkers Predict Neurological Morbidity in Diagnostically Diverse Pediatric Intensive Care Unit Patients. Au AK, Bell MJ, Fink EL, Aneja RK, Kochanek PM, Clark RSB. Neurocrit Care. 2017 Jun 13. [Epub ahead of print].
  35. Modeling Fast-scan Cyclic Voltammetry Data from Electrically Stimulated Dopamine Neurotransmission Data Using QNsim1.0. Harun R, Grassi CM, Munoz MJ, Wagner AK. J Vis Exp. 2017 Jun 5;(124).
  36. Translating biomarkers from research to clinical use in pediatric neurocritical care: focus on traumatic brain injury and cardiac arrest. Prout AJ, Wolf MS, Fink EL. Curr Opin Pediatr. 2017 Jun;29(3):272-279.
  37. Brain-Specific Serum Biomarkers Predict Neurological Morbidity in Diagnostically Diverse Pediatric Intensive Care Unit Patients.Au AK, Bell MJ, Fink EL, Aneja RK, Kochanek PM, Clark RSB.Neurocrit Care. 2017 Jun 13.  [Epub ahead of print]
  38. IGF-1 mediated neurogenesis involves a novel Rit1/Akt/Sox2 cascade. Mir S, Cai W, Carlson SW, Saatman KE, Andres DA, Scientific Reports, May 2017, 7:3283 
  39. Brain injury results in lower levels of melatonin receptors subtypes MT1 and MT2. Osier ND, Pham L, Pugh BJ, Puccio A, Ren D, Conley YP, Alexander S, Dixon CE. Neurosci Lett. 2017 May 22;650:18-24.
  40. In vivo transduction of neurons with TAT-UCH-L1 protects brain against controlled cortical impact injury. Liu H, Rose ME, Ma X, Culver S, Dixon CE, Graham SH. PLoS One. 2017 May 24;12(5):e0178049.
  41. Guiding Pediatric Critical Care Medicine Toward a Bigger “Impression” in 2017 and Beyond. Kochanek PM, Kudchadkar SR, Kissoon N.Pediatr Crit Care Med. 2017 May;18(5):403-404.
  42. Titrating the dose of oxygen after severe traumatic brain injury in the era of precision medicine. Kochanek PM, Bayir H. J Neurotrauma. 2017 May 24. [Epub ahead of print]
  43. Dietary Supplementation With Nonfermentable Fiber Alters the Gut Microbiota and Confers Protection in Murine Models of Sepsis. Morowitz MJ, Di Caro V, Pang D, Cummings J, Firek B, Rogers MB, Ranganathan S, Clark RSB, Aneja RK. Crit Care Med. 2017 May;45(5):e516-e523.
  44. Effects of DHA on Hippocampal Autophagy and Lysosome Function After Traumatic Brain Injury.Yin Y, Li E, Sun G, Yan HQ, Foley LM, Andrzejczuk LA, Attarwala IY, Hitchens TK, Kiselyov K, Dixon CE, Sun D. Mol Neurobiol. 2017 Apr 1. [Epub ahead of print]
  45. Polynitroxylated Pegylated Hemoglobin-A Novel, Small Volume Therapeutic for Traumatic Brain Injury Resuscitation: Comparison to Whole Blood and Dose Response Evaluation. Brockman EC, Jackson TC, Dixon CE, Bayɪr H, Clark RS,Vagni V, Feldman K, Byrd C, Ma L, Hsia C, Kochanek PM. J Neurotrauma. 2017 Apr 1;34(7):1337-1350. 
  46. Refining environmental enrichment to advance rehabilitation based research after experimental traumatic brain injury. Radabaugh HL, LaPorte MJ, Greene AM, Bondi CO, Lajud N, Kline AE. Exp Neurol. 2017 Apr 27;294:12-18. [Epub ahead of print]
  47. International Survey of Critically Ill Children With Acute Neurologic Insults: The Prevalence of Acute Critical Neurological Disease in Children: A Global Epidemiological Assessment Study. Fink EL, Kochanek PM, Tasker RC, Beca J, Bell MJ, Clark RS, Hutchison J, Vavilala MS, Fabio A, Angus DC, Watson RS; Prevalence of Acute critical Neurological disease in children: A Global Epidemiological Assessment (PANGEA) Investigators. Pediatr Crit Care Med. 2017 Apr;18(4):330-342.
  48. Delirium in Critically Ill Children: An International Point Prevalence Study. Traube C, Silver G, Reeder RW, Doyle H, Hegel E, Wolfe HA, Schneller C, Chung MG, Dervan LA, DiGennaro JL, Buttram SD, Kudchadkar SR, Madden K, Hartman ME, deAlmeida ML, Walson K, Ista E, Baarslag MA, Salonia R, Beca J, Long D, Kawai Y, Cheifetz IM, Gelvez J, Truemper EJ, Smith RL, Peters ME, O’Meara AM, Murphy S, Bokhary A, Greenwald BM, Bell MJ. Crit Care Med. 2017 Apr;45(4):584-590. 
  49. Derivation and Validation of a Serum Biomarker Panel to Identify Infants With Acute Intracranial Hemorrhage. Berger RP,Pak BJ, Kolesnikova MD, Fromkin J, Saladino R, Herman BE, Pierce MC, Englert D, Smith PT, Kochanek PM. JAMA Pediatr. 2017 Apr 10:e170429.
  50. Ventricular Fibrillation Cardiac Arrest Produces a Chronic Striatal Hyperdopaminergic State that is Worsened by Methylphenidate Treatment. Nora GJ, Harun R, Fine DF, Hutchison D, Grobart AC, Stezoski JP, Munoz M, Kochanek PM, Leak RK, Drabek T, Wagner AK . J Neurochem. 2017 Apr 26.
  51. Abusive Head Trauma and Mortality-An Analysis From an International Comparative Effectiveness Study of Children With Severe Traumatic Brain Injury. Miller Ferguson N, Sarnaik A, Miles D, Shafi N, Peters MJ, Truemper E, Vavilala MS, Bell MJ, Wisniewski SR, Luther JF, Hartman AL, Kochanek PM; Investigators of the Approaches and Decisions in Acute Pediatric Traumatic Brain Injury (ADAPT) Trial. Crit Care Med. 2017 Apr 20.
  52. ABCB1 genotype is associated with fentanyl requirements in critically Ill children. Horvat CM, Au AK, Conley YL, Kochanek PM, Li L, Poloyac SL, Empey PE, Clark RS. Pediatr Res. 2017 Apr 7. 
  53. A “Metamorphosis” in Our Approach to Treatment Is Not Likely to Result From a Meta-Analysis of the Use of Therapeutic Hypothermia in Severe Traumatic Brain Injury. Wallisch JS, Kochanek PM. Crit Care Med. 2017 Apr;45(4):744-745.
  54. Lithium increases hippocampal SNARE protein abundance after traumatic brain injury. Carlson SW, Yan HQ, CE Dixon. Exp Neurol, March 2017, 289:55-63. 
  55. Hemodialysis Clinic Social Networks, Sex Differences, and Renal Transplantation.Gillespie A, Fink EL, Traino HM, Uversky A, Bass SB, Greener J, Hunt J, Browne T, Hammer H, Reese PP, Obradovic Z.Am J Transplant. 2017 Mar 18.  [Epub ahead of print]
  56. Pediatric Multiple Organ Dysfunction in Resource Limited Settings. Fink EL, Kissoon N. Pediatr Crit Care Med. 2017 Mar;18(3_suppl Suppl 1):S83-S85.
  57. The far-reaching scope of neuroinflammation after traumatic brain injury. Simon DW, McGeachy MJ, Bayır H, Clark RS,Loane DJ, Kochanek PM. Nat Rev Neurol. 2017 Mar;13(3):171-191.
  58. Biochemical signaling by remote ischemic conditioning of the arm versus thigh: Is one raise of the cuff enough? Dezfulian C, Taft M, Corey C, Hill G, Krehel N, Rittenberger JC, Guyette FX, Shiva S. Redox Biol. 2017 Mar 18;12:491-498.
  59. Translating biomarkers from research to clinical use in pediatric neurocritical care: focus on traumatic brain injury and cardiac arrest. Prout AJ, Wolf MS, Fink EL. Curr Opin Pediatr. 2017 Mar 17.
  60. Pediatric Multiple Organ Dysfunction in Resource Limited Settings. Fink EL, Kissoon N. Pediatr Crit Care Med. 2017 Mar;18(3_suppl Suppl 1):S83-S85.
  61. Sulfonylurea Receptor-1: A Novel Biomarker for Cerebral Edema in Severe Traumatic Brain Injury. Jha RM, Puccio AM, Chou SH, Chang CH, Wallisch JS, Molyneaux BJ, Zusman BE, Shutter LA, Poloyac SM, Janesko-Feldman KL, Okonkwo DO, Kochanek PM. Crit Care Med. 2017 Mar;45(3):e255-e264
  62. Physical and occupational therapy utilization in a pediatric intensive care unit. Cui LR, LaPorte M, Civitello M, Stanger M, Orringer M, Casey F 3rd, Kuch BA, Beers SR, Valenta CA, Kochanek PM, Houtrow AJ, Fink EL. J Crit Care. 2017 Mar 7;40:15-20. 
  63. Psychometric evaluation of the pediatric and parent-proxy Patient-Reported Outcomes Measurement Information System and the Neurology and Traumatic Brain Injury Quality of Life measurement item banks in pediatric traumatic brain injury.Bertisch H, Rivara FP, Kisala PA, Wang J, Yeates KO, Durbin D, Zonfrillo MR, Bell MJ, Temkin N, Tulsky DS. Qual Life Res. 2017 Mar 7.
  64. Pediatric cardiac arrest due to drowning and other respiratory etiologies: Neurobehavioral outcomes in initially comatose children. Slomine BS, Nadkarni VM, Christensen JR, Silverstein FS, Telford R, Topjian A, Koch JD, Sweney J, Fink EL,Mathur M, Holubkov R, Dean JM, Moler FW; Therapeutic Hypothermia after Pediatric Cardiac Arrest THAPCA Trial Investigators. Resuscitation. 2017 Mar 6. pii: S0300-9572(17)30104-1. 
  65. Global assessment of oxidized free fatty acids in brain reveals an enzymatic predominance to oxidative signaling after trauma. Anthonymuthu TS, Kenny EM, Amoscato AA, Lewis J, Kochanek PM, Kagan VE, Bayır H. Biochim Biophys Acta. 2017 Mar 24.
  66. Adenosine production by brain cells. Jackson EK, Kotermanski SE, Menshikova EV, Dubey RK, Jackson TC, Kochanek PM. J Neurochem. 2017 Mar 13. 
  67. Contemporary animal models of cardiac arrest: A systematic review. Vognsen M, Fabian-Jessing BK, Secher N, Løfgren B, Dezfulian C, Andersen LW, Granfeldt A. Resuscitation. 2017 Apr;113:115-123. doi: 10.1016/j.resuscitation.2017.01.024. Epub 2017 Feb 15. 
  68. Cerebrospinal Fluid NLRP3 is Increased After Severe Traumatic Brain Injury in Infants and Children. Wallisch JS, Simon DW, Bayır H, Bell MJ, Kochanek PM, Clark RS.Neurocrit Care. 2017 Feb 8.
  69. α-Tocopherol transfer protein mediates protective hypercapnia in murine ventilator-induced lung injury. Otulakowski G, Engelberts D, Arima H, Hirate H, Bayir H, Post M, Kavanagh BP. Thorax. 2017 Feb 3.
  70. Acute Management of Refractory and Unstable Pediatric Supraventricular Tachycardia. Lewis J, Arora G, Tudorascu DL, Hickey RW, Saladino RA, Manole MD. J Pediatr. 2017 Feb;181:177-182.e2. 
  71. Tripartite Stratification of the Glasgow Coma Scale in Children with Severe Traumatic Brain Injury and Mortality: An Analysis from a Multi-Center Comparative Effectiveness Study. Murphy S, Thomas NJ, Gertz SJ, Beca J, Luther JF, Bell MJ, Wisniewski SR, Hartman AL, Tasker RC. J Neurotrauma. 2017 Feb 27.
  72. Examining Emergency Department Treatment Processes in Severe Pediatric Traumatic Brain Injury. Ajdari A, Boyle LN, Kannan N, Rowhani-Rahbar A, Wang J, Mink R, Ries B, Wainwright M, Groner JI, Bell MJ, Giza C, Zatzick DF, Ellenbogen RG, Mitchell PH, Rivara FP, Vavilala MS. J Health Qual. 2017 Feb 3. 
  73. The Brain and Hypothermia-From Aristotle to Targeted Temperature Management. Kochanek PM, Jackson TC. Crit Care Med. 2017 Feb;45(2):305-310
  74. Lipidomics Characterization of Biosynthetic and Remodeling Pathways of Cardiolipins in Genetically and Nutritionally Manipulated Yeast Cells. Tyurina YY, Lou W, Qu F, Tyurin VA, Mohammadyani D, Liu J, Hüttemann M, Frasso MA, Wipf P, Bayir H, Greenberg ML, Kagan VE. ACS Chem Biol. 2017 Jan 20;12(1):265-281.
  75.  ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition. Doll S, Proneth B, Tyurina YY, Panzilius E, Kobayashi S, Ingold I, Irmler M, Beckers J, Aichler M, Walch A, Prokisch H, Trümbach D, Mao G, Qu F, Bayir H, Füllekrug J, Scheel CH, Wurst W, Schick JA, Kagan VE, Angeli JP, Conrad M. Nat Chem Biol. 2017 Jan;13(1):91-98. 
  76. Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis. Kagan VE, Mao G, Qu F, Angeli JP, Doll S, Croix CS, Dar HH, Liu B, Tyurin VA, Ritov VB, Kapralov AA, Amoscato AA, Jiang J, Anthonymuthu T, Mohammadyani D, Yang Q, Proneth B, Klein-Seetharaman J, Watkins S, Bahar I, Greenberger J, Mallampalli RK, Stockwell BR, Tyurina YY, Conrad M, Bayır H. Nat Chem Biol. 2017 Jan;13(1):81-90. 
  77. Known unknowns of cardiolipin signaling: The best is yet to come. Maguire JJ, Tyurina YY, Mohammadyani D, Kapralov AA, Anthonymuthu TS, Qu F, Amoscato AA, Sparvero LJ, Tyurin VA, Planas-Iglesias J, He RR, Klein-Seetharaman J,Bayır H, Kagan VE. Biochim Biophys Acta. 2017 Jan;1862(1):8-24. 
  78. Elimination of the unnecessary: Intra- and extracellular signaling by anionic phospholipids. Kagan VE, Bayır H, Tyurina YY, Bolevich SB, Maguire JJ, Fadeel B, Balasubramanian K. Biochem Biophys Res Commun. 2017 Jan 15;482(3):482-490. 
  79. Magic angle spinning 31P NMR spectroscopy reveals two essentially identical ionization states for the cardiolipin phosphates in phospholipid liposomes. Kooijman EE, Swim LA, Graber ZT, Tyurina YY, Bayır H, Kagan VE. Biochim Biophys Acta. 2017 Jan;1859(1):61-68. 
  80. The benefits of youth are lost on the young cardiac arrest patient. Griffith B, Kochanek P, Dezfulian C. F1000Res. 2017 Jan 25;6:77.
  81. Epidemiology of Comorbid Conditions Among Adults 50 Years and Older With Traumatic Brain Injury. Kumar RG, Juengst SB, Wang Z, Dams-OʼConnor K, Dikmen SS, OʼNeil-Pirozzi TM, Dahdah MN, Hammond FM, Felix ER, Arenth PM, Wagner AK. J Head Trauma Rehabil. 2017 Jan 5.
  82. Probabilistic Matching Approach to Link Deidentified Data from a Trauma Registry and a Traumatic Brain Injury Model System Center. Kesinger MR, Kumar RG, Ritter AC, Sperry JL, Wagner AK. Am J Phys Med Rehabil. 2017 Jan;96(1):17-24.
  83. Therapeutic Hypothermia after In-Hospital Cardiac Arrest in Children. Moler FW, Silverstein FS, Holubkov R, Slomine BS, Christensen JR, Nadkarni VM, Meert KL, Browning B, Pemberton VL, Page K, Gildea MR, Scholefield BR, Shankaran S, Hutchison JS, Berger JT, Ofori-Amanfo G, Newth CJ, Topjian A, Bennett KS, Koch JD, Pham N, Chanani NK, Pineda JA, Harrison R, Dalton HJ, Alten J, Schleien CL, Goodman DM, Zimmerman JJ, Bhalala US, Schwarz AJ, Porter MB, Shah S, Fink EL, McQuillen P, Wu T, Skellett S, Thomas NJ, Nowak JE, Baines PB, Pappachan J, Mathur M, Lloyd E, van der Jagt EW, Dobyns EL, Meyer MT, Sanders RC Jr, Clark AE, Dean JM; THAPCA Trial Investigators. N Engl J Med. 2017 Jan 26;376(4):318-329. 
2016
  1. Galantamine and Environmental Enrichment Enhance Cognitive Recovery after Experimental Traumatic Brain Injury But Do Not Confer Additional Benefits When Combined. de la Tremblaye PB, Bondi CO, Lajud N, Cheng JP, Radabaugh HL, Kline AE. J Neurotrauma. 2016 Dec 20. doi: 10.1089/neu.2016.4790.
  2. Incidence and risk factors of posttraumatic seizures following traumatic brain injury: A Traumatic Brain Injury Model Systems Study. Ritter AC, Wagner AK, Fabio A, Pugh MJ, Walker WC, Szaflarski JP, Zafonte RD, Brown AW, Hammond FM, Bushnik T, Johnson-Greene D, Shea T, Krellman JW, Rosenthal JA, Dreer LE. Epilepsia. 2016 Dec;57(12):1968-1977.
  3. Autophagy Biomarkers Beclin 1 and p62 are Increased in Cerebrospinal Fluid after Traumatic Brain Injury. Au AK, Aneja RK, Bayır H, Bell MJ, Janesko-Feldman K, Kochanek PM, Clark RS.Neurocrit Care. 2016 Dec 20. [Epub ahead of print]
  4. Traumatic brain injuries. Blennow K, Brody DL, Kochanek PM, Levin H, McKee A, Ribbers GM, Yaffe K, Zetterberg H. Nat Rev Dis Primers. 2016 Nov 17;2:16084.
  5. Hidden Perils of the “Wild Blue Yonder” after Traumatic Brain Injury. Kochanek PM, Bayır H.J Neurotrauma. 2016 Oct 1;33(19):1729-1731.
  6. A Dopamine Pathway Gene Risk Score for Cognitive Recovery Following Traumatic Brain Injury: Methodological Considerations, Preliminary Findings, and Interactions With Sex. Myrga JM, Failla MD, Ricker JH, Dixon CE, Conley YP, Arenth PM, Wagner AK. J Head Trauma Rehabil. 2016 Sep-Oct;31(5):E15-29.
  7. The Controlled Cortical Impact Model of Experimental Brain Trauma: Overview, Research Applications, and Protocol. Osier N, Dixon CE. Methods Mol Biol. 2016;1462:177-92.
  8. Enduring Disturbances in Regional Cerebral Blood Flow and Brain Oxygenation at 24 Hours after Asphyxial Cardiac Arrest in Developing Rats. Foley LM, Clark RS, Vazquez AL, Hitchens TK, Alexander H, Ho C, Kochanek PM, Manole MD. Pediatr Res. 2016 Sep 16. [Epub ahead of print]
  9. ABCC8 Single Nucleotide Polymorphisms are Associated with Cerebral Edema in Severe TBI. Jha RM, Puccio AM, Okonkwo DO, Zusman BE, Park SY, Wallisch J, Empey PE, Shutter LA, Clark RS, Kochanek PM, Conley YP. Neurocrit Care. 2016 Sep 27. [Epub ahead of print]
  10. Strategic Planning for Research in Pediatric Critical Care.Tamburro RF, Jenkins TL, Kochanek PM. Pediatr Crit Care Med. 2016 Sep 27. [Epub ahead of print]
  11. Intermittent treatment with haloperidol or quetiapine does not disrupt motor and cognitive recovery after experimental brain trauma. Weeks JJ, Carlson LJ, Radabaugh HL, de la Tremblaye PB, Bondi CO, Kline AE. Behav Brain Res. 2016 Sep 21. [Epub ahead of print]
  12. Abbreviated environmental enrichment confers neurobehavioral, cognitive, and histological benefits in brain-injured female rats. Radabaugh HL, Carlson LJ, O’Neil DA, LaPorte MJ, Monaco CM, Cheng JP, de la Tremblaye PB, Lajud Avila N, Bondi CO, Kline AE. 2016 Sep 28. [Epub ahead of print]
  13. Imaging Mass Spectrometry Reveals Loss of Polyunsaturated Cardiolipins in the Cortical Contusion, Hippocampus and Thalamus after Traumatic Brain Injury. Sparvero LJ, Amoscato AA, Fink AB, Anthonymuthu T, New LE, Kochanek PM, Watkins S, Kagan VE, Bayır H. J Neurochem. 2016 Sep 3. [Epub ahead of print]
  14. Effect of Hypothermia and Targeted Temperature Management on Drug Disposition and Response Following Cardiac Arrest: A Comprehensive Review of Preclinical and Clinical Investigations. Anderson KB, Poloyac SM, Kochanek PM, Empey PE.Ther Hypothermia Temp Manag. 2016 Sep 13. [Epub ahead of print]
  15. Combined Neurotrauma Models: Experimental Models Combining Traumatic Brain Injury and Secondary Insults. Simon DW, Vagni VM, Kochanek PM, Clark RS. Methods Mol Biol. 2016;1462:393-411.
  16. The Controlled Cortical Impact Model of Experimental Brain Trauma: Overview, Research Applications, and Protocol. Osier N, Dixon CE. Methods Mol Biol. 2016;1462:177-92.
  17. Mechanistic characterization of nitrite-mediated neuroprotection after experimental cardiac arrest. Dezfulian C, Kenny E, Lamade A, Misse A, Krehel N, St Croix C, Kelley EE, Jackson TC, Uray T, Rackley J, Kochanek PM, Clark RS, Bayir H. J Neurochem. 2016 Aug 10. [Epub ahead of print]
  18. Pediatric Critical Care Medicine: Accomplishments and Important New Initiatives. Kochanek PM.Pediatr Crit Care Med. 2016 Aug;17(8):709.
  19. Severe traumatic brain injury in children: a vision for the future. Bell MJ, Wisniewski SR. Intensive Care Med. 2016 Oct;42(10):1618-20. Epub 2016 Jun 2.
  20. Validation of the Pittsburgh Infant Brain Injury Score for Abusive Head Trauma. Berger RP, Fromkin J, Herman B, Pierce MC, Saladino RA, Flom L, Tyler-Kabara EC, McGinn T, Richichi R, Kochanek PM.Pediatrics. 2016 Jul;138(1). pii: e20153756. Epub 2016 Jun 23.
  21. 5-hydroxytryptamine1A (5-HT1A) receptor agonists: A decade of empirical evidence supports their use as an efficacious therapeutic strategy for brain trauma. Cheng JP, Leary JB, Sembhi A, Edwards CM, Bondi CO, Kline AE. Brain Res. 2016 Jun 1;1640(Pt A):5-14.
  22. Combination therapies for neurobehavioral and cognitive recovery after experimental traumatic brain injury: Is more better? Kline AE, Leary JB, Radabaugh HL, Cheng JP, Bondi CO. Prog Neurobiol. 2016 Jul;142:45-67.
  23. Serum Concentrations of Ubiquitin C-Terminal Hydrolase-L1 and Glial Fibrillary Acidic Protein after Pediatric Traumatic Brain Injury.Mondello S, Kobeissy F, Vestri A, Hayes RL, Kochanek PM, Berger RP.Sci Rep. 2016 Jun 20;6:28203.
  24. Probenecid, an organic anion transporter 1 and 3 inhibitor, increases plasma and brain exposure of N-acetylcysteine.Hagos FT, Daood MJ, Ocque JA, Nolin TD, Bayir H, Poloyac SM, Kochanek PM, Clark RS, Empey PE.Xenobiotica. 2016 Jun 9:1-8. [Epub ahead of print]
  25. Secondary Changes After Injury and Temperature. Batchelor P, Dietrich WD, Kochanek PM, Lundbye J.Ther Hypothermia Temp Manag. 2016 Jun;6(2):58-62.
  26. Variation in Anticonvulsant Selection and Electroencephalographic Monitoring Following Severe Traumatic Brain Injury in Children-Understanding Resource Availability in Sites Participating in a Comparative Effectiveness Study. Kurz JE, Poloyac SM, Abend NS, Fabio A, Bell MJ, Wainwright MS; for Investigators for the Approaches and Decisions in Acute Pediatric TBI Trial. Pediatr Crit Care Med. 2016 May 27. [Epub ahead of print]
  27. The Therapeutic Efficacy of Environmental Enrichment and Methylphenidate Alone and in Combination after Controlled Cortical Impact Injury. Leary JB, Bondi CO, LaPorte MJ, Carlson LJ, Radabaugh HL, Cheng JP,Kline AE.
  28. Relative to Typical Antipsychotic Drugs, Aripiprazole Is a Safer Alternative for Alleviating Behavioral Disturbances After Experimental Brain Trauma. Phelps TI, Bondi CO, Mattiola VV, Kline AE.Neurorehabil Neural Repair. 2016 May 24. [Epub ahead of print]
  29. Variation in PPP3CC genotype is associated with long-term recovery after severe brain injury.Osier N, Bales JW, Pugh BJ, Shin S, Wyrobek J, Puccio AM, Okonkwo DO, Ren D, Alexander SA, Conley YP, Dixon CE. J Neurotrauma. 2016 May 25. [Epub ahead of print]
  30. Combining the Antipsychotic Drug Haloperidol and Environmental Enrichment after Traumatic Brain Injury Is a Double-Edged Sword. Folweiler KA, Bondi CO, Ogunsanya EA, LaPorte MJ, Leary JB, Radabaugh HL, Monaco CM, Kline AE. J Neurotrauma. 2016 Apr 20. [Epub ahead of print]
  31. Rosiglitazone attenuates inflammation and CA3 neuronal loss following traumatic brain injury in rats.Liu H, Rose ME, Culver S, Ma X, Dixon CE, Graham SH.
  32. Insight into Pre-Clinical Models of Traumatic Brain Injury Using Circulating Brain Damage Biomarkers: Operation Brain Trauma Therapy. Mondello S, Shear DA, Bramlett HM, Dixon CE, Schmid KE, Dietrich WD, Wang KK, Hayes RL, Glushakova O, Catania M, Richieri SP, Povlishock JT, Tortella FC, Kochanek PM. J Neurotrauma. 2016 Mar 15;33(6):595-605.
  33. Effectiveness of Pharmacological Therapies for Intracranial Hypertension in Children With Severe Traumatic Brain Injury-Results From an Automated Data Collection System Time-Synched to Drug Administration.Shein SL, Ferguson NM, Kochanek PM, Bayir H, Clark RS, Fink EL, Tyler-Kabara EC, Wisniewski SR, Tian Y, Balasubramani GK, Bell MJ.Pediatr Crit Care Med. 2016 Mar;17(3):236-45.
  34. Levetiracetam Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy.Browning M, Shear DA, Bramlett HM, Dixon CE, Mondello S, Schmid KE, Poloyac SM, Dietrich WD, Hayes RL, Wang KKW, Povlishock JT, Tortella FC, Kochanek PM. J Neurotrauma 33:581-594, 2016.
  35. Synthesis of Findings, Current Investigations, and Future Directions: Operation Brain Trauma Therapy.Kochanek PM, Bramlett HM, Shear DA, Dixon CE, Mondello S, Dietrich WD, Hayes RL, Wang KK, Poloyac SM, Empey PE, Povlishock JT, Mountney A, Browning M, Deng-Bryant Y, Yan HQ, Jackson TC, Catania M, Glushakova O, Richieri SP, Tortella FC.J Neurotrauma. 2016 Mar 15;33(6):606-14.
  36. Cyclosporine Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Dixon CE, Bramlett HM, Dietrich WD, Shear DA, Yan HQ, Deng-Bryant Y, Mondello S, Wang KK, Hayes RL, Empey PE, Povlishock JT, Tortella FC, Kochanek PM. J Neurotrauma. 2016 Mar 15;33(6):553-66.
  37. Nicotinamide Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy.Shear DA, Dixon CE, Bramlett HM, Mondello S, Dietrich WD, Deng-Bryant Y, Schmid KE, Wang KK, Hayes RL, Povlishock JT, Kochanek PM, Tortella FC. J Neurotrauma. 2016 Mar 15;33(6):523-37.
  38. Erythropoietin Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Bramlett HM, Dietrich WD, Dixon CE, Shear DA, Schmid KE, Mondello S, Wang KK, Hayes RL, Povlishock JT, Tortella FC, Kochanek PM.J Neurotrauma. 2016 Mar 15;33(6):538-52.
  39. Probenecid and N-Acetylcysteine Prevent Loss of Intracellular Glutathione and Inhibit Neuronal Death after Mechanical Stretch Injury In Vitro. Du L, Empey PE, Ji J, Chao H, Kochanek PM, Bayır H, Clark RS.J Neurotrauma. 2016 Mar 22. [Epub ahead of print]
  40. Intracranial Hypertension and Cerebral Hypoperfusion in Children with Severe Traumatic Brain Injury: Thresholds and Burden in Accidental and Abusive Insults. Miller Fergusion N, Shein SL, Kochanek PM, Luther J, Wisniewski SR, Clark RS, Tyler-Kabara EC, Adelson PD, Bell MJ. Pediatr Crit Care Med. 2016 Mar 29 [Epub ahead of print].
  41. Oxygen: A Luxurious Life-Giving and Potentially Toxic Gas. Sanchez-de-Toledo J, Bayir H. Pediatr Crit Care Med. 2016 Apr;17(4):371-2.
  42. Therapies targeting lipid peroxidation in traumatic brain injury.Anthonymuthu TS, Kenny EM, Bayır H.Brain Res. 2016 Jun 1;1640(Pt A):57-76.
  43. Brain Injury and Revcovery. Kline AE, Bondi CO. Brain Res. 2016 Feb 25 [Epub ahead of print].
  44. Ultrastructure of diaschisis lesions following traumatic brain injury.Wiley CA, Bissel SJ, Lesniak A, Dixon CE, Franks J, Stolz DB, Sun M, Wang G, Switzer Iii RC, Kochanek PM, Murdoch GH.J Neurotrauma. 2016 Feb 25. [Epub ahead of print]
  45. Probenecid and N-acetylcysteine Prevent Loss of Intracellular Glutathione and Inhibit Neuronal Death after Mechanical Stretch Injury In Vitro. Du L, Empey P, Ji J, Chao H, Kochanek PM, Bayir H, Clark R. J Neurotrauma. 2016 Feb 2. [Epub ahead of print].
  46. Purines: Forgotten Mediators in Traumatic Brain Injury. Jackson EK, Boison D, Schwarzschild MA, Kochanek PM. J Neurochem. 2016 Jan 26. doi: 10.1111/jnc.13551. [Epub ahead of print].
  47. Exploratory Study of Serum Ubiquitin Carboxyl-Terminal Esterase L1 and Glial Fibrillary Acidic Protein for Outcome Prognostication after Pediatric Cardiac Arrest. Fink EL, Berger RP, Clark RS, Watson RS, Angus DC, Panigrahy A, Richichi R, Callaway CW, Bell MJ, Mondello S, Hayes RL, Kochanek PM. Resuscitation. 2016 Feb 5. [Epub ahead of print].

    Pediatric Critical Care Medicine 2016: Growth and Further Specialization. Kochanek PM.Pediatr Crit Care Med. 2016 Jan;17(1):1.

  48. Purines: Forgotten Mediators in Traumatic Brain Injury. Jackson EK, Boison D, Schwarzschild MA, Kochanek PM. J Neurochem. 2016 Jan 26. [Epub ahead of print].
  49. Genetic Variation in the Vesicular Monoamine Transporter: Preliminary Associations With Cognitive Outcomes After Severe Traumatic Brain Injury. Markos SM, Failla MD, Ritter AC, Dixon CE, Conley YP, Ricker JH, Arenth PM, Juengst SB, Wagner AK. J Head Trauma Rehabil. 2016 Jan 29. [Epub ahead of print].
  50. Operation Brain Trauma Therapy: Simvastatin Treatment in Traumatic Brain Injury. Mountney A, Bramlett HM, Dixon CE, Mondello S. Dietrich WD, Caudle K, Empey PE, Poloyac SM, Hayes RL, Povlishock JT, Tortella FC, Kochanek PM, Shear DA. J Neurotrauma 2016 Jan 20 [Epub ahead of print].
  51. Effects of Depression and Antidepressant Use on Cognitive Deficits and Functional Cognition Following Severe Traumatic Brain Injury. Failla MD, Juengst SB, Graham KM, Arenth PM, Wagner AK. J Head Trauma Rehabil. 2016 Jan 29. [Epub ahead of print].
  52. Brain-Derived Neurotrophic Factor (BDNF) in Traumatic Brain Injury-Related Mortality: Interrelationships Between Genetics and Acute Systemic and Central Nervous System BDNF Profiles. Failla MD, Conley YP, Wagner AK. Neurorehabil Neural Repair. 2016 Jan;30(1):83-93.
2015
  1. Traumatic brain injury research highlights in 2015. Kochanek PM, Clark RS.Lancet Neurol. 2016 Jan;15(1):13-5. Epub 2015 Dec 8.
  2. Administration of DHA Reduces Endoplasmic Reticulum Stress-Associated Inflammation and Alters Microglial or Macrophage Activation in Traumatic Brain Injury. Harvey LD, Yin Y, Attarwala IY, Begum G, Deng J, Yan HQ, Dixon CE, Sun D. ASN Neuro. 2015 Dec 18;7(6). 
  3. Principal Components Derived from CSF Inflammatory Profiles Predict Outcome in Survivors after Severe Traumatic Brain Injury.Kumar RG, Rubin JE, Berger RP, Kochanek PM, Wagner AK. Brain Behav Immun. 2015 Dec 16. [Epub ahead of print]
  4. Effectiveness of Pharmacological Therapies for Intracranial Hypertension in Children With Severe Traumatic Brain Injury-Results From an Automated Data Collection System Time-Synched to Drug Administration. Shein SL, Ferguson NM, Kochanek PM, Bayir H, Clark RS, Fink EL, Tyler-Kabara EC, Wisniewski SR, Tian Y, Balasubramani GK, Bell MJ. Pediatr Crit Care Med. 2015 Dec 15. [Epub ahead of print]
  5. Insight into Preclinical Models of Traumatic Brain Injury Using Circulating Brain Damage Biomarkers: Operation Brain Trauma Therapy. Mondello S, Shear DA, Bramlett HM, Dixon CE, Schmid Maj KE, Dietrich WD, Wang KK, Hayes RL, Glushakova O, Catania M, Richieri S, Povlishock J, Tortella FC, Kochanek PM. J Neurotrauma. 2015 Dec 16. [Epub ahead of print]
  6. Levetiracetam Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Browning M, Shear DA, Bramlett HM, Dixon CE, Mondello S, Schmid Maj KE, Poloyac SM, Dietrich WD, Hayes RL, Wang KK, Povlishock J, Tortella FC, Kochanek PM. J Neurotrauma. 2015 Dec 16. [Epub ahead of print]
  7. Synthesis of Findings, Current Investigations, and Future Directions: Operation Brain Trauma Therapy. Kochanek PM, Bramlett HM, Shear DA, Dixon CE, Mondello S, Dietrich WD, Hayes RL, Wang KK, Poloyac SM, Empey P, Povlishock J, Mountney A, Browning M, Deng-Bryant Y, Yan HQ, Jackson TC, Catania M, Glushakova O, Richieri S, Tortella FC. J Neurotrauma. 2015 Dec 16. [Epub ahead of print]
  8. Cyclosporine Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy.Dixon CE, Bramlett HM, Dietrich WD, Shear DA, Yan HQ, Deng-Bryant Y, Mondello S, Wang KK, Hayes RL, Empey P, Povlishock J, Tortella FC, Kochanek PM. J Neurotrauma. 2015 Dec 16. [Epub ahead of print]
  9. Nicotinamide Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy.Shear DA, Bramlett HM, Dixon CE, Dietrich WD, Deng-Bryant Y, Schmid Maj KE, Mondello S, Wang KK, Hayes RL, Povlishock J, Kochanek PM, Tortella FC. J Neurotrauma. 2015 Dec 16. [Epub ahead of print]
  10. Erythropoietin Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy.Bramlett HM, Dietrich WD, Dixon CE, Shear DA, Schmid Maj KE, Mondello S, Wang KK, Hayes RL, Povlishock J, Tortella FC, Kochanek PM. J Neurotrauma. 2015 Dec 16. [Epub ahead of print]
  11. Hidden Perils of the “Wild Blue Yonder” after Traumatic Brain Injury. Kochanek PM, Bayır H. J Neurotrauma. 2015 Dec 17. [Epub ahead of print]
  12. Operation Brain Trauma Therapy: Approach to Modeling, Therapy Evaluation, Drug Selection, and Biomarker Assessments for a Multicenter Pre-Clinical Drug Screening Consortium for Acute Therapies in Severe Traumatic Brain Injury. Kochanek PM, Bramlett HM, Dixon CE, Shear DA, Dietrich WD, Schmid KE, Mondello S, Wang KK, Hayes RL, Povlishock JT, Tortella FC. J Neurotrauma. 2015 Dec 10. [Epub ahead of print]
  13. Repetitive Mild Traumatic Brain Injury in the Developing Brain: Effects on Long-Term Functional Outcome and Neuropathology. Fidan E, Lewis J, Kline AE, Garman RH, Alexander H, Cheng JP, Bondi CO, Clark RS, Dezfulian C,Kochanek PM, Kagan VE, Bayır H. J Neurotrauma. 2015 Dec 1. [Epub ahead of print]
  14. Mitochondrial Redox Opto-Lipidomics Reveals Mono-Oxygenated Cardiolipins as Pro-Apoptotic Death Signals. Mao G, Qu F, St Croix CM, Tyurina YY, Planas-Iglesias J, Jiang J, Huang Z, Amoscato AA, Tyurin VA, Kapralov AA, Cheikhi A, Maguire J, Klein-Seetharaman J, Bayir H, Kagan VE. ACS Chem Biol. 2015 Dec 23. [Epub ahead of print]
  15. Catecholaminergic based therapies for functional recovery after TBI. Osier ND, Dixon CE. Brain Res. 2015 Dec 19. [Epub ahead of print] 
  16. Simvastatin Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Mountney A, Bramlett HM, Dixon CE, Mondello S, Dietrich WD 3rd, Wang KK, Caudle KL, Empey P, Poloyac SM, Hayes RL, Povilshock J, Tortella FC, Kochanek PM, Shear DA. J Neurotrauma. 2015 Nov 5 [Epub ahead of print].
  17. Pediatric Neurocritical Care: A Short Survey of Current Perceptions and Practices. Murphy SA, Bell MJ, Whalen MJ, Noviski N. Neurocritical Care. 2015 Oct 23(2):149-58.
  18. Approach to Modeling, Therapy Evaluation, Drug Selection, and Biomarker Assessments, for a Multi-Center Pre-Clinical Drug Screening Consortium for Acute Therapies in Severe Traumatic Brain Injury: Operation Brain Trauma Therapy. Kochanek PM, Bramlett HM, Dixon CE, Shear DA, Dietrich WD 3rd, Schmid K, Mondello S, Wang KK, Hayes RL, Povlishock J, Tortella St FC. J Neurotrauma 2015 Oct 6. [Epub ahead of print]
  19. It Seems Like Resuscitation Happened Ages Ago-Chronic Critical Illness in Children: Digging in for hte Long Haul. Fink EL, Kochanek PM. Crit Care Med 2015 Sep; 43(9):2035-6.
  20. Pilot Feasibility of an mHealth System for Conduction Ecological Momentary Assessment of Mood-Related Symptoms Following Traumatic Brain Injury. Juengst SB, Graham KM, Pulantara IW, McCue M, Whyte EM, Dicianno BE, Paramanto B, Arenth OM, Skidmore ER, Wagner AK. Brain Inj 2015 Aug 7:1-11 [Epub ahead of print].
  21. Defects of Lipid Synthesis Are Linked to the Age-Dependant Demyelination Caused by Lamin B1. Rolyan H, Tyurina Y, Hernande M, Amoscato AA, Sparvero L, Nmezi BC, Estecio MR, Lin K, Chen J, He RR, Gong P, Rigatti LH,  Dupree J, Bayir H, Kagan VE, Casaccia P, Padiath QS.J Neurosci. 2015 Aug 26;35(34):12002-17
  22. Cold Stress Protein RBM3 Responds to Temperature Change in an Ultra-Sensitive Manner in Young Neurons. Jackson TC, Manole MD, Kotermanski SE, Clark RS, Kochanek PM. Neuroscience. 2015 Oct 1;305268-78. [Epub Aug 8]
  23. Traumatic Brain Injury Impairs Soluble N-ethylmaleimide-Sensitive Factor Attachment Protein Receptor Complex Formation and Alters Synaptic Vesicle Distribution in the Hippocampus.Carlson SW, Yan H, Ma M, Li Y, Henchir J, Dixon CE. J Neurotrauma. 2015 Aug 27. [Epub ahead of print]
  24. Preliminary Associations Between Brain-Derived Neurotrophic Factor, Memory Impairment, Functional Cognition, and Depressive Symptoms Following Severe TBI. Failla MD, Juengst SB, Arenth PM, Wagner AK. Neurorehabil Neural Repair. 2015 Aug 13 [Epub ahead of print].
  25. Tackling the challenges of Clinical Trials for Severe Traumatic Brain Injury in Children: Screening, Phenotyping, and Adapting. Crit Care Med. 2015 Jul;43(7):1544-6.
  26. Repetitive mild traumatic brain injury in the developing brain: effects on long-term functional outcome and neuropathology. Fidan E, Lewis J, Kline AE, Garman RH, Alexander H, Cheng JP, Bondi CO, Clark R, Dezfulian C,Kochanek PM, Kagan VE, Bayır H. J Neurotrauma. 2015 Jul 27. [Epub ahead of print]
  27. IL-1β associations with posttraumatic epilepsy development: A genetics and biomarker cohort study. Diamond ML, Ritter AC, Failla MD, Boles JA, Conley YP, Kochanek PM, Wagner AK. Epilepsia. 2015 Jul;56(7):991-1001. 
  28. Ischemia-induced autophagy contributes to neurodegeneration in cerebellar Purkinje cells in the developing rat brain and in primary cortical neurons in vitro. Au AK, Chen Y, Du L, Smith CM, Manole MD, Baltagi SA, Chu CT, Aneja RK, Bayır H, Kochanek PM, Clark RS. Biochim Biophys Acta. 2015 Sep;1852(9):1902-11. Epub 2015 Jun 11.
  29. 20-Hydroxyeicosatetraenoic Acid Inhibition by HET0016 Offers Neuroprotection, Decreases Edema, and Increases Cortical Cerebral Blood Flow in a Pediatric Asphyxial Cardiac Arrest Model in Rats.Shaik JS, Poloyac SM, Kochanek PM, Alexander H, Tudorascu DL, Clark RS, Manole MD. J Cereb Blood Flow Metab. 2015 Jun 10. [Epub ahead of print]
  30. Genetic variation in the adenosine regulatory cycle is associated with posttraumatic epilepsy development. Diamond ML, Ritter AC, Jackson EK, Conley YP, Kochanek PM, Boison D, Wagner AK. Epilepsia. 2015 Jun 4. [Epub ahead of print]
  31. Alterations in Cholinergic Pathways and Therapetic Strategies Targeting Cholinergic System after Traumatic Brain Injury Injury. Shin SS, Dixon CE. J Neurotrauma. 2015 June 29 [Epub ahead of print]
  32. Management of pediatric traumatic brain injury. Mtaweh H, Bell MJ. Curr Treat Options Neurol. 2015 May;17(5):348.
  33. Genetic variation in the adenosine regulatory cycle is associated with posttraumatic epilepsy development.Diamond ML, Ritter AC, Jackson EK, Conley YP, Kochanek PM, Boison D, Wagner AK. Epilepsia. 2015 Jun 4. doi: 10.1111/epi.13044. [Epub ahead of print]
  34. Socioeconomic factors associated with outcome after cardiac arrest in patients under the age of 65. Uray T, Mayr FB, Fitzgibbon J, Rittenberger JC, Callaway CW, Drabek T, Fabio A, Angus DC,Kochanek PM, Dezfulian C. Resuscitation. 2015 May 21;93:14-19. doi: 10.1016/j.resuscitation.2015.04.032. [Epub ahead of print]
  35. Schwann Cells Metabolize Extracellular 2′,3′-cAMP to 2′-AMP.Verrier JD, Kochanek PM, Jackson EK. J Pharmacol Exp Ther. 2015 May 21. pii: jpet.115.225219. [Epub ahead of print]
  36. Posttraumatic Brain Injury Cognitive Performance Is Moderated by Variation Within ANKK1 and DRD2 Genes.Failla MD, Myrga JM, Ricker JH, Dixon CE, Conley YP, Wagner AK. J Head Trauma Rehabil. 2015 Apr 29. [Epub ahead of print]
  37. Chronic Histopathological and Behavioral Outcomes of Experimental Traumatic Brain Injury in Adult Male Animals. Osier ND, Carlson SW, DeSana A, Dixon CE.J Neurotrauma. 2015 Apr 15. [Epub ahead of print]
  38. Therapeutic Hypothermia after Out-of-Hospital Cardiac Arrest in Children. Moler FW, Silverstein FS, Holubkov R, Slomine BS, Christensen JR, Nadkarni VM, Meert KL, Clark AE, Browning B, Pemberton VL, Page K, Shankaran S, Hutchison JS, Newth CJ, Bennett KS, Berger JT, Topjian A, Pineda JA, Koch JD, Schleien CL, Dalton HJ, Ofori-Amanfo G, Goodman DM, Fink EL, McQuillen P, Zimmerman JJ, Thomas NJ, van der Jagt EW, Porter MB, Meyer MT, Harrison R, Pham N, Schwarz AJ, Nowak JE, Alten J, Wheeler DS, Bhalala US, Lidsky K, Lloyd E, Mathur M, Shah S, Wu T, Theodorou AA, Sanders RC Jr, Dean JM; THAPCA Trial Investigators. N Engl J Med. 2015 May 14;372(20):1898-908.  [Epub ahead of print Apr 25]
  39. Traumatic Brain Injury Impairs SNARE Complex Formation and Alters Synaptic Vesicle Distribution in the Hippocampus. Carlson SW, Yan HQ, Ma X, Li Y, Henchir JJ, Dixon CE.J Neurotrauma. 2015 Apr 29. [Epub ahead of print]
  40. Evaluation of Electronic Medical Record Vital Sign Data Versus a Commercially Available Acuity Score in Predicting Need for Critical Intervention at a Tertiary Children’s Hospital. da Silva YS, Fiedor Hamilton M, Horvat C, Fink EL, Palmer F, Nowalk AJ, Winger DG, Clark RS. Pediatr Crit Care Med. 2015 Apr 21. [Epub ahead of print]
  41. 20-HETE is associated with unfavorable outcomes in subarachnoid hemorrhage patients. Donnelly MK, Crago EA, Conley YP, Balzer JR, Ren D, Ducruet AF,Kochanek PM, Sherwood PR, Poloyac SM. J Cereb Blood Flow Metab. 2015 Apr 29. 
  42. Expression of ATP-Binding Cassette Transporters B1 and C1 after Severe Traumatic Brain Injury in Humans. Willyerd FA, Empey P, Philbrick A, Ikonomovic M, Puccio AM, Kochanek PM, Okonkwo DO, Clark R. J Neurotrauma. 2015 Apr 19. [Epub ahead of print]
  43. Cerebrospinal Fluid Markers of Macrophage and Lymphocyte Activation After Traumatic Brain Injury in Children. Newell E, Shellington DK, Simon DW, Bell MJ, Kochanek PM, Feldman K, Bayir H, Aneja RK, Carcillo JA, Clark RS. Pediatric Crit Care Med. 2015 Apr 6 [Epub ahead of print.]
  44. Detection of PHLPP1α/β in Human and Mouse Brain by Different Anti-PHLPP1 Antibodies. Jackson TC, Bayir H, Ikonomivic MD, Janesko-Feldman K, Mi Z, Gao T, Jackson EK, Kochanek PM. Sci Rep. Apr 1;5:9377.
  45. Progesterone for neuroprotection in pediatric traumatic brain injury. Robertson CL, Fidan E, Stanely RM, Noje C, Bayir H. Pediatr Crit Car Med. 2015 Mar;16:236-44.
  46. Targeted Temperature Management in Pediatric Central Nervous System Disease.Newmyer R, Mendelson J, Pang D, Fink EL.Curr Treat Options Pediatr. 2015 Mar 1;1(1):38-47.
  47. Serum D-dimer concentrations are increased after pediatric traumatic brain injury.Berger RP, Fromkin J, Rubin P, Snyder J, Richichi R, Kochanek P. J Pediatr. 2015 Feb;166(2):383-8.
  48. Emerging therapies in traumatic brain injury. Kochanek PM, Jackson TC, Ferguson NM, Carlson SW, Simon DW, Brockman EC, Ji J, Bayir H, Poloyac SM, Wagner AK, Kline AE, Empey PE, Clark RS, Jackson EK, Dixon CE. Semin Neurol. 2015 Feb; 35(1):83-100.
  49. It might be time to let cooler heads prevail after mild traumatic brain injury or concussion. Kochanek PM, Jackson TC, Exp Neurol. 2015 Feb 27. [Epub ahead of print]
  50. Patterns of multiorgan dysfunction after pediatric drowning. Mtaweh H, Kochanek PM. Carcillo JA, Bell MJ, Fink EL. Resuscitation. 2015 May, 90:91-6.  [Epub ahead of print Feb 19] 
  51. Visual Priming Enhances the Effects of Nonspatial Cognitive Rehabilitation Training on Spatial Learning after Experimental Traumatic Brain Injury.  Edwards CM, Kumar K, Koesarie K, Brough E, Ritter AC, Brayer SW, Thiels E, Skidmore ER, Wagner AK. Neurorehabil Neural Repair. 2015 Feb 9 [Epub ahead of print].
  52. The Nuclear Splicing Factor RNA Binding Motif 5 promotes Caspase Activation in Human Neuronal Cells, and Increases after Traumatic Brain Injury in MIce. Jackson TC, Du L, Janesko-Feldman K, Vagni VA, Dezfulian C, Poloyac SM, Jackson EK, Clark RS, Kochanek PM. J Cereb Blood Flow Metab, 2015 Jan 14 [Epub ahead of print].
  53. Effect of Administration of Neuromuscular Blocking Agents in Children with Severe Traumatic Brain Injury on Acute Complication Rates and Outcomes: A Secondary Analysis from a Randomized, Controlled Trial of Therapeutic Hypothermia. Chin KH, Bell MJ, Wisniewski SR, Goundappa BG, Kochanek PM, Beers SR, Brown SD, Adelson PD: for the Pediatric Traumatic Brain Injury Consortium: Hypothermia Investigators. 2015 Jan 16 [Epub ahead of print].
  54. Neuroprotective effects of collagen matrix in rats after traumatic brain injury. Shin SS, Grandi R, Henchir J, Yan HQ, Badylak SF, Dixon CE. Restor Neurol Neurosci. 2015 Jan 26 [Epub ahead of print].
  55. The Influence of Genetic Variants on Striatal Dopamine Transporter and D2 Receptor Binding after TBI. Wagner AK, Scanlon JM, Becker CR, Ritter AC, Niyonkuru C, Dixon CE, Conley YP, Price JC. J Cereb Blood Flow Metab. 2015 Jan;35(1):166.
  56. Progesterone for Neuroprotection in Pediatric Traumatic Brain Injury. Robertson CL, Fidan E, Stanely RM, Noje C, Bayir H. Pediatr Crit Care Med. 2015 Jan 9 [Epub ahead of print].
  57. Divergent long-term consequences of chronic treatment with haloperidol, risperidone, and bromocriptine on traumatic brain injury-induced cognitive deficits. Phelps TI, Bondi CO, Ahmed RH, Olugbade YT, Kline AE. J Neurotrauma. 2015 Apr 15;32(8):590-7. . Epub 2015 Jan 8.
2014
  1. Bayir H, Yildiz I.The importance of platelet markers on hospital mortality in intensive care unit patients.J Crit Care. 2014 Dec 3.[Epub ahead of print]
  2. Harun R, Grassi CM, Munoz MJ, Torres GE, Wagner AK.Neurobiological model of stimulated dopamine neurotransmission to interpret fast-scan cyclic voltammetry data.Brain Res. 2014 Dec 16. [Epub ahead of print]
  3. Kumar RG, Diamond ML, Boles JA, Berger RP, Tisherman S, Kochanek PM, Wagner AK.Acute CSF Interleukin-6 Trajectories after TBI: Associations with Neuroinflammation, Polytrauma, and Outcome.Brain Behav Immun. 2014 Dec 30. [Epub ahead of print]
  4. Osier N, Carlson SW, DeSana AJ, Dixon CE.Chronic Histopathological and Behavioral Outcomes of Experimental Traumatic Brain Injury in Adult Male Animals.J Neurotrauma. 2014 Dec 9. [Epub ahead of print]
  5. Cheng JP, Leary JB, Sembhi A, Edwards CM, Bondi CO, Kline AE.5-hydroxytryptamine1A (5-HT1A) receptor agonists: A decade of empirical evidence supports their use as an efficacious therapeutic strategy for brain trauma. Brain Res. 2015 Nov 21. [Epub ahead of print] 
  6. Bondi CO, Semple BD, Noble-Haeusslein LJ, Osier ND, Carlson SW, Dixon CE, Giza CC, Kline AE.Found in translation: Understanding the biology and behavior of experimental traumatic brain injury. Neurosci Biobehav Rev. 2015 Nov;58:123-46. 
  7. Berger RP, Fromkin J, Rubin P, Snyder J, Richichi R, Kochanek P.Serum D-Dimer Concentrations Are Increased after Pediatric Traumatic Brain Injury.J Pediatr. 2014 Nov 20.[Epub ahead of print]
  8. Drabek T, Kochanek PM.Improving Outcomes from Resuscitation: From H-H to TH to H2.Circulation. 2014 Nov 3.[Epub ahead of print]
  9. Wiley CA, Bonneh-Barkay D, Dixon CE, Lesniak A, Wang G, Bissel SJ, Kochanek PM.Role for mammalian chitinase 3-like protein 1 in traumatic brain injury.Neuropathology. 2014 Nov 7. [Epub ahead of print]
  10. Ji J, Baart S, Vikulina AS, Clark RS, Anthonymuthu TS, Tyurin VA, Du L, St Croix CM, Tyurina YY, Lewis J, Skoda EM, Kline AE, Kochanek PM, Wipf P, Kagan VE, Bayır H.Deciphering of mitochondrial cardiolipin oxidative signaling in cerebral ischemia-reperfusion.J Cereb Blood Flow Metab. 2014 Nov 19.  [Epub ahead of print]
  11. Drabek T, Wilson CD, Janata A, Stezoski JP, Janesko-Feldman K, Garman RH, Tisherman SA, Kochanek PM.Unique Brain Region-Dependent Cytokine Signatures After Prolonged Hypothermic Cardiac Arrest in Rats.Ther Hypothermia Temp Manag. 2014 Nov 25. [Epub ahead of print]
  12. Newell EA, Exo JL, Verrier JD, Jackson TC, Gillespie DG, Janesko-Feldman K, Kochanek PM, Jackson EK.2′,3′-cAMP, 3′-AMP, 2′-AMP and adenosine inhibit TNF-α and CXCL10 production from activated primary murine microglia via A2A receptors.Brain Res. 2014 Nov 3. [Epub ahead of print]
  13. Phelps TI, Bondi CO, Ahmed RH, Olugbade YT, Kline AE. Divergent long-term consequences of chronic treatment with haloperidol, risperidone, and bromocriptine on traumatic brain injury-induced cognitive deficits. J Neurotrauma, 2014 Oct 2 [Epub ahead of print.]
  14. Vavilala MS, Kernic MA, Wang J, Kannan N, Mink RB, Wainwright MS, Groner JI, Bell MJ, Giza CC, Zatzick DF, Ellenbogen RG, Boyle LN, Mitchell PH, Rivara FP; Pediatric Guidline Adherence and Outcomes Study.Acute care clinical indicators associated with discharge outcomes in children with severe traumatic brain injury.Crit Care Med, 2014 Oct;42(10)2258-66.
  15. Trakas EV, Fink EL. Serum biomarkers of brain injury: a call for collaboration. Pediatr Crit Care Med. 2014 Sep; 15(7):672-3.
  16. Weiss SL, Fitzgerald JC, Faustino EV, Festa MS, Fink EL, Jouvet P, Kissoon N, Marshall J, Nadkarni VM, Thomas NJ; Pediatric Acute Lung Injury and Sepsis Investigators Network and Australia and New Zealand Intensive Care Society Investigators. Understanding the global epidemiology of pediatric critical illness: the power, pitfalls, and practicallities of point prevalence studies. Pediatr Crit Care Med. 2014 Sep; 15(7):660-66.
  17. Zou H, Hurwitz M, Fowler L, Wagner AK. Abbreviated levetiracetam treatmen effects on behavioral and histological outcomes after experimental TBI. Brain Inj. 2015;29(1):78-85 
  18. Brayer SW, Ketcham S, Zou H, Hurwitz M, Henderson C, Fuletra J, Kumar K, Skidmore E, Thiels E, Wagner AK. Developing a clinically relevant model of congnitive training after experimental traumatic brain injury.Neurorehabil Neural Repair. 2014 Sep 19. [Epub ahead of print.]
  19. Gao W, Lu C, Kochanek PM, Berger RP. Serum amyloid A is increased in children with abusive head trauma a gel-based proteomic analysis. Pediatr Res. 2014 Sep;76(3)280-6.
  20. Santarsieri M, Kumar RG, Kochanek PM, Berga S, Wagner AK. Variable neuroendocrin-immune dysfunction i individuals with unfavorable outcome after severe traumatic brain injury. Brain Behave Immun. 2014 Sep 16 [Epub ahead of print]
  21. Shin SS, Dixon CE, Okonkwo DO, Richardson RM. Neurostimulation for traumatic brain injury. J Neurosurg.2014 Aug 29: 1-13. [Epub ahead of print]
  22. Carlson SW, Madathil SK, Sama DM, Gao X, Chen J, Saatman KE.Conditional overexpression of insulin-like growth factor-1 enhances hippocampal neurogenesis and restores immature neuron dendritic processes after traumatic brain injury.J Neuropathol Exp Neurol. 2014 Aug;73(8):734-46.
  23. Wagner AK, Scanlon JM, Becker CR, Ritter AC, Niyonkuru C, Dixon CE, Conley YP, Price JC.The influence of genetic variants on striatal dopamine transporter and D2 receptor binding after TBI.J Cereb Blood Flow Metab.2014 Aug;34(8):1328-39. doi: 10.1038/jcbfm.2014.87. [Epub ahead of print]
  24. Sanchez-de-Toledo J, Chrysostomou C, Munoz R, Lichtenstein S, Sao-Avilés CA, Wearden PD, Morell VO,Clark RS, Toney N, Bell MJ.Cerebral regional oxygen saturation and serum neuromarkers for the prediction of adverse neurologic outcome in pediatric cardiac surgery.Neurocrit Care. 2014 Aug;21(1):133-9.
  25. Da Silva YS, Horvat CM, Dezfulian C.Thiamine Deficiency as a Cause of Persistent Hyperlactatemia in a Parenteral Nutrition-Dependent Patient.JPEN J Parenter Enteral Nutr. 2014 Aug 5. [Epub ahead of print]
  26. Fink EL, Houtrow A. A new era of personalized rehabilitation in the PICU. Pediatr Crit Care Med. 2014 Jul; 15(6)571-2.
  27. Trzeciak S, Glaspey LJ, Dellinger RP, Duflinger P, Anderson K, Dezfulian C, Roberts BW. Chansky ME, Parrillo JE, Hollenberg SM. Randomized controlled trial of inhaled nitric oxide for the treatment of microcirculatory dysfunction in patients with sepsis. Crit Care MEd, 2014 Jul 30. [Epub ahead of print.]
  28. Wagner AK.A Rehabilomics framework for personalized and translational rehabilitation research and care for individuals with disabilities: Perspectives and considerations for spinal cord injury.J Spinal Cord Med. 2014 Jul 16. [Epub ahead of print]
  29. Failla MD, Kumar RG, Peitzman AB, Conley YP, Ferrell RE, Wagner AK.Variation in the BDNF Gene Interacts With Age to Predict Mortality in a Prospective, Longitudinal Cohort with Severe TBI.Neurorehabil Neural Repair.2015 Mar-Apr;29(3):234-46.. [Epub Jul 2014]
  30. Monaco CM, Gebhardt KM, Chlebowski SM, Shaw KE, Cheng JP, Henchir JJ, Zupa MF, Kline AE.A combined therapeutic regimen of buspirone and environmental enrichment is more efficacious than either alone in enhancing spatial learning in brain-injured pediatric rats.J Neurotrauma. 2014 Dec 1;31(23):1934-41 [Epub July 2014]
  31. Vavilala MS, Kernic MA, Wang J, Kannan N, Mink RB, Wainwright MS, Groner JI, Bell MJ, Giza CC, Zatzick DF, Ellenbogen RG, Boyle LN, Mitchell PH, Rivara FP;for the Pediatric Guideline Adherence and Outcomes Study.Acute Care Clinical Indicators Associated With Discharge Outcomes in Children With Severe Traumatic Brain Injury.Crit Care Med. 2014 Oct;42(10):2258-66. [Epub July 2014]
  32. Amoscato AA, Sparvero LJ, He RR, Watkins S, Bayir H, Kagan VE.Imaging mass spectrometry of diversified cardiolipin molecular species in the brain.Anal Chem. 2014 Jul 1;86(13):6587-95. 
  33. Jackson EK, Cheng D, Verrier JD, Janesko-Feldman K, Kochanek PM.Interactive Roles of CD73 and Tissue Non-Specific Alkaline Phosphatase in the Renal Vascular Metabolism of 5′-AMP.Am J Physiol Renal Physiol. 2014 Sep 15;307(6):F680-5. [Epub July2014]
  34. Tress EE, Clark RS, Foley LM, Alexander H, Hickey RW, Drabek T, Kochanek PM, Manole MD.Blood brain barrier is impermeable to solutes and permeable to water after experimental pediatric cardiac arrest.Neurosci Lett. 2014 Jun 14;578C:17-21.
  35. Uray T, Kochanek PM.Finding a faster and safer way to “catch a cold” after cardiac arrest: We may be getting closer.Resuscitation. 2014 Sep;85(9):1131-3. [Epub Jul 2014]
  36. Juengst SB, Kumar RG, Arenth PM, Wagner AK. Exploratory associations with Tumor Necrosis Factor-α, disinhibition and suicidal endorsement after traumatic brain injury. Brain Behav Immun.2014 Oct;41:134-43 [Epub Jun 2014]
  37. Wagner AK, Sowa G.Rehabilomics Research: A Model for Translational Rehabilitation and Comparative Effectiveness Rehabilitation Research.Am J Phys Med Rehabil. 2014 Oct;93(10):913-6.  [Epub Jun 4]
  38. Au AK, Bell MJ.Severe postoperative hyponatremia after pediatric intracranial tumor surgery-is this preventable?*. Pediatr Crit Care Med. 2014 Jun;15(5):497-8.
  39. Walko TD 3rd, Bola RA, Hong JD, Au AK, Bell MJ, Kochanek PM, Clark RS, Aneja RK.Cerebrospinal Fluid Mitochondrial DNA: A Novel DAMP in Pediatric Traumatic Brain Injury.Shock. 2014 Jun;41(6):499-503.
  40. Yousef KM, Balzer JR, Crago EA, Poloyac SM, Sherwood PR.Transcranial regional cerebral oxygen desaturation predicts delayed cerebral ischaemia and poor outcomes after subarachnoid haemorrhage: A correlational study.Intensive Crit Care Nurs. 2014 Jun 2.
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  42. Lindberg DM, Berger RP, Reynolds MS, Alwan RM, Harper NS; Examining Siblings To Recognize Abuse (ExSTRA) Investigators.Yield of Skeletal Survey by Age in Children Referred to Abuse Specialists.J Pediatr.2014 Mar 12.[Epub ahead of print]
  43. Jackson EK, Gillespie DG, Mi Z, Cheng D, Bansal R, Janesko-Feldman K, Kochanek PM.Role of 2′,3′-Cyclic Nucleotide 3′-Phosphodiesterase in the Renal 2′,3′-cAMP-Adenosine Pathway.Am J Physiol Renal Physiol. 2014 May 7. [Epub ahead of print]
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  46. Tyurina YY, Poloyac SS, Tyurin VA, Kapralov AA, Jiang J, Anthonymuthu TS, Kapralova VI, Vikulina AS, Jung MY, Epperly MW, Mohammadyani D,Klein-Seetharaman J, Jackson TC, Kochanek PM, Pitt BR, Greenberger JS, Vladimirov YA, Bayır H, Kagan VE. A mitochondrial pathway for biosynthesis of lipid mediators.Nat Chem. 2014 Jun;6(6):542-52. [Epub ahead of print.]
  47. Foster KA, Recker M, Lee P, Bell MJ, Tyler-Kabara E.Factors Associated with Hemispheric Hypodensity after Subdural Hematoma following Abusive Head Trauma in Children.J Neurotrauma. 2014 Apr 2. [Epub ahead of print]
  48. Drabek T, Foley LM, Janata A, Stezoski J, Kevin Hitchens T, Manole MD, Kochanek PM.Global and regional differences in cerebral blood flow after asphyxial versus ventricular fibrillation cardiac arrest in rats using ASL-MRI.Resuscitation. 2014 Apr 12. [Epub ahead of print]
  49. Diamond ML, Ritter AC, Failla MD, Boles JA, Conley YP, Kochanek PM, Wagner AK.IL-1β associations with posttraumatic epilepsy development: A genetics and biomarker cohort study.Epilepsia. 2014 Apr 22. [Epub ahead of print]
  50. Shein S, Shellington DK, Exo J, Jackson TC, Wisniewski SR, Jackson E, Vagni VA, Bayir H, Clark R, Dixon CE, Janesko KL, Kochanek PM. Hemorrhagic shock shifts the serum cytokine profile from pro-to anti-inflammatory after experimental traumatic brain injury in mice.J Neurotrauma. 2014 Apr 28. [Epub ahead of print]
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  53. Jiang J, Bakan A, Kapralov AA, Ishara Silva K, Huang Z, Amoscato AA, Peterson J, Krishna Garapati V, Saxena S, Bayir H, Atkinson J, Bahar I, Kagan VE.Designing inhibitors of cytochrome c/cardiolipin peroxidase complexes: mitochondria-targeted imidazole-substituted fatty acids.Free Radic Biol Med. 2014 Mar 12;71C:221-230.  2014 Jun;71:221-30. [Epub March 2014]
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  55. Simon DW, Clark RS, Watson RR. No pain, no gain in pediatric sepsis? Pediatr Crit Care Med. 2014 Mar; 15(3):264-6.
  56. Fink EL, Berger RP, Clark RS, Watson RS, Angus DC, Richichi R, Panigrahy A, Callaway CW, Bell MJ, Kochanek PM. Serum biomarkers of brain injury to classify outcome after pediatric cardiac arrest. Crit Care Med. 2014 Mar;42(3)664-74.
  57. Stoyanovsky DA, Sparvero LJ, Amoscato AA, He RR, Watkins S, Pitt BR, Bayir H, Kagan V. Improved spatial resolution of marix-assosiated laser desorption/ionization imaging of lipids in the brain by alkylated derivatives of 2,5-dihydroxybenzoic acid. Rapid Commun Mass Spectrom. 2014 Mar;28(5):403-412.
  58. Drabek T, Janata A, Wilson CD, Stezoski J, Janesko-Feldman K, Tisherman SA, Foley LM, Verrier JD,Kochanek PM. Minocycline attenduates brain tissue levels of TNF-α produced by neurons after prolonged hypothermic cardiac arrest in rats. Resuscitation. 2014 Feb;85(2):284-91.
  59. Juengst SB, Kumar RG, Failla MD, Goyal A, Wagner AK. Acute inflammatory biomarker profiles predict depression risk following moderate to severe traumatic brain injury. J Head Trauma Rehabil. 2015 May-Jun;30(3):207-18.  [Epub Feb 2015]
  60. Zelnick L, Morrison LJ, Devlin SM, Bulger EM, Brasel KJ, Sheehan K, Minei JP, Kerby JD, Tisherman SA, Rizoli S, Karmy-Jones R, can Heest R, Newgard CD. Addressing the challenges of obtaining functional outcomes in traumatic brain injury research: missign data patterns, timing of follow-up, and three prognostic models. J Neurotrauma 2014 Jun 1;31(11):1029-38. [Epub Feb 2014].
  61. Bondi CO, Klitsch KC, Leary J, Kline AE. Environmental enrichment as a viable neurorehabilitation strategy for experimental traumatic brain injury. J Neurotrauma. 2014 May 15;31(10):873-88. [Epub Feb 2014].
  62. Callaway CW. Studying community consultation in exception from informed consent trials*. Crit Care Med. 2014 Feb;42(2):451-3.
  63. Suffoletto B, Hu J, Guyette M, Callaway C. Factors contributing to emergency department care within 30 days of hopsital discharge and potential ways to prevent it: Differences in perspectives of patients, caregivers, and emergency physicians. J Hosp Med. 2014 May;9(5):315-9. [Epub Feb 2014].
  64. Santarsieri M, Niyonkuru C, McCullough EH, Dobos JA, Dixon CE, Berga SL, Wagner AK. Cerebrospinal fluid cortisol and progesterone profiles and outcomes prognostication after severe traumatic brain injury. J Neurotrauma. 2014 Apr 15;31(8):699-712. [Epub Feb 2014]
  65. Tisherman SA. If some hypothermia is good, more hypothermia must be better, right?* Crit Care Med. 2014 Feb;42(2):489-90.
  66. Janata A, Magnet IA, Uray T, Stezoski JP, Janesko-Feldman K, Tisherman SA, Kochanek PM, Drabek T.Regional TNFα Mapping in the brain reveals the striatum as a neuroinflammatory target after ventricular fibrillation cardiac arrest. Resuscitation 2014 May;85(5):694-701.  [Epub Feb. 2014]
  67. Alexander SA, Ren D, Gunn SR, Kochanek PM, Tate J, Ikonomovic M, Conley YP.Interleukin 6 and apolipoprotein e as predictors of acute brain dysfunction and survival in critical care patients. Am J Crit Care.2014 Jan;23(1):49-57.
  68. Kochanek PM, Jackson TC. Will the next breakthrough for neuroprotection after cardiac arrest come out of thin air? Shock. 2014 Jan;41(1):85-6.
  69. Mtaweh H, Smith R, Kochanek PM, Wisniewski SR, Fabio A, Vavilala MS, Adelson PD, Toney NA, Bell MJ.Energy expenditure in children after severe traumatic brain injury. Pediatr Crit Care Med.  2014 Mar;15(3):242-9. [Epub Jan. 2014]
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  74. Diaz-Arrastia R, Kochanek PM, Bergold P, Kenney K, Marx CE, Grimes CJ, Loh LT, Adam LT, Oskvig D,Curley KC, Salzer W.Pharmacotherapy of traumatic brain injury: state of the science and the road forward: report of the Department of Defense Neurotrauma Pharmacology Workgroup.J Neurotrauma. 2014 Jan 15;31(2):135-58.
2013
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  6. Manole MD, Kochanek PM, Bayir H, Alexander H, Dezfulian C, Fink EL, Bell MJ, Clark RS. Brain tissue oxygenation monitering identifies cortical hypoxia and thalamic hyperoxia after experimental pediatric cardiac arrest. Pediatr Res. [Epub Nov. 2013]
  7. Sanchez-de-Toledo J, Chrysostomou C, Munoz R, Lichtenstein S, Sao-Aviles CA, Wearden PD, Morell VO, Clark RS, Toney N, Bell MJ. Cerebral regional oxygen saturation and serum neuromarkers for the prediction of adverse neurologic outcome in pediatric cardiac surgery. Neurocrit Care. [Epub Nov. 2013]
  8. Cleve WV, Kernic MA, Ellenbogen RG, Wang J, Zatzick DF, Bell MJ, Wainwrifht MS, Groner JL, Mink RB, Giza CC, Boyle LN, Mitchell PH, Rivara FP, Vavilala MS: PEGASUS (Pediatric Guideline Adherence and Outcomes) Project. National variability in intracranial pressure monitoring and craniotomy for children with moderate to severe traumatic brain injury. Neurosurgery. 2013 NoV; 73(5):746-52.
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  63. Berger R, McGinn T. Deciding whether to screen for abusive head trauma: do we need a clinical decision rule?*. Pediatr Crit Care Med. 2013 Feb;14(2):230-1.
  64. Darrah SD, Miller MA, Ren D, Hoh NZ, Scanlon JM, Conley YP, Wagner AK. Genetic variability in glutamic acid decarboxylase genes: associations with post-traumatic seizures after severe TBI. Epilepsy Res. 2013 Feb; 103(2-3):180-94.
  65. Guerra-Wallace MM, Casey FL 3rd, Bell MJ, Fink EL, Hickey RW. Hyperoxia and Hypoxia in Children Resuscitated From Cardiac Arrest. Pediatr Crit Care Med. [Epub Feb. 2013]
  66. Heidemann SM, Holubkov R, Meert KL, Dean JM, Berger J, Bell M, Anand KJ, Zimmerman J, Newth CJ, Harrison R, Willson DF, Nicholson C, Carcillo J; and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Collaborative Pediatric Critical Care Research Network (CPCCRN). Baseline Serum Concentrations of Zinc, Selenium, and Prolactin in Critically Ill Children. Pediatr Crit Care Med. [Epub Feb. 2013]
  67. Shin SS, Bales JW, Yan HQ, Kline AE, Wagner AK, Lyons-Weiler J, Dixon CE. The Effect of Environmental Enrichment on Substantia Nigra Gene Expression after Traumatic Brain Injury in Rats. J Neurotrauma. [Epub Feb. 2013]
  68. Thampatty BP, Klamerus MM, Oberly PJ, Feldman KL, Bell MJ, Tyler-Kabara EC, Adelson PD, Clark RS, Kochanek PM, Poloyac SM. Hypothermia Decreases Cerebrospinal Fluid Asymmetric Dimethylarginine Levels in Traumatic Brain Injury Children. Pediatr Crit Care Med. [Epub Feb. 2013]
  69. Adelson PD, Fellows-Mayle W, Kochanek PM, Dixon CE. Morris water maze function and histologic characterization of two age-at-injury experimental models of controlled cortical impact in the immature rat. Childs Nerv Syst. 2013 Jan;29(1):43-53.
  70. Jackson TC, Verrier JD, Kochaenk PM. Anthraquinone-2-sulfonic acid (AQ2S) is A Novel Neurotherapeutic Agent. Cell Death Dis.  2013 Jan;10;4:e451.
  71. Matthews M, Bondi C, Torres G, Moghaddam B. Reduced presynaptic dopamine activity in adolescent dorsal striatum. Neuropsychopharmacology. [Epub Jan. 2013]
  72. Monaco CM, Mattiola VV, Folweiler KA, Tay JK, Yelleswarapu NK, Curatolo LM, Matter AM, Cheng JP, Kline AE. Environmental enrichment promotes robust functional and histological benefits in female rats after controlled cortical impact injury. Exp Neurol. [Epub Jan. 2013]
  73. Tavarez MM, Saladino RA, Gaines BA, Manole MD. Prevalence, clinical features and management of pediatric magnetic foreign body ingestions. J Emerg Med. 2013 Jan;44(1):261-8.
  74. Vavilala MS, Kernic MA, Rivara FP, Zatzick DF, Bell MJ, Wainwright M, Groner JI, Giza CC, Mink R, Ellenbogen R, Boyle L, Mitchell P, Kannan N. Triage of Children with Moderate and Severe Traumatic Brain Injury to Trauma Centers. J Neurotrauma. [Epub Jan. 2014]
2012
  1. Bell MJ, Pineda JA, Vavilala MS, Wainwright MS, Doctor A, Stanley R, Thompson AE. Neurocritical Care Research Networks-Pediatric Considerations. Neurocrit Care. 2012 Dec, 17:468-9; author reply 470.
  2. Topjian AA, Berg RA, Bierens JJ, Branche CM, Clark RS, Friberg H, Hoedemaekers CW, Holzer M, Katz LM, Knape JT, Kochanek PM, Nadkarni V, van der Hoeven JG, Warner DS. Brain Resuscitation in the Drowning Victim. Neurocrit Care. 2012 Dec;17(3):441-67.
  3. Liu H, Sarnaik SM, Manole MD, Chen Y, Shinde SN, Li W, Rose M, Alexander H, Chen J, Clark RS, Graham SH, Hickey RW. Increased cytochrome c in rat cerebrospinal fluid after cardiac arrest and its effects on hypoxic neuronal survival. Resuscitation. 2012 Dec;83(12):1491-6.
  4. Kochanek PM, Bayır H. Optimizing oxygenation and ventilation after cardiac arrest in “little adults.”Resuscitation. 2012 Dec, 8:1425-6.
  5. Su E, Bell MJ, Kochanek PM, Wisniewski SR, Bayir H, Clark RS, Adelson PD, Tyler-Kabara EC, Janesko-Feldman KL, Berger RP.  Increased CSF Concentrations of Myelin Basic Protein After TBI in Infants and Children: Absence of Significant Effect of Therapeutic Hypothermia.  Neurocritical Care. 2012 Aug 14. 2012 Nov;10(5):383-91.
  6. Cheng JP, Shaw KE, Monaco CM, Hoffman AN, Sozda CN, Olsen AS, Kline AE. A Relatively Brief Exposure to Environmental Enrichment after Experimental Traumatic Brain Injury Confers Long-Term Cognitive Benefits. J Neurotrauma. 2012 Nov 20, 29:2684-8.
  7. Shein SL, Bell MJ, Su E, Kochanek PM, Exo J. Intracranial monitoring and continuous data collection. Crit Care Med. 2012 Nov, 40:3115-6.
  8. Alam HB, Pusateri AE, Kindzelski A, Egan D, Hoots K, Andrews MT, Rhee P, Tisherman S, Mann K, Vostal J,Kochanek PM, Scalea T, Deal V, Sheppard F, Sopko G; and the HYPOSTAT workshop participants.Hypothermia and hemostasis in severe trauma: A new crossroads workshop report. J Trauma Acute Care Surg. 2012 Oct, 73:809-817.
  9. Su E, Shoykhet M, Bell MJ. Severe hypernatremia in a hospitalized child: munchausen by proxy. Pediatr Neurol. 2010 Oct,43(4):270-3.
  10. Jackson EK, Cheng D, Mi Z, Verrier JD, Janesko-Feldman K, Kochanek PM. Role of A1 receptors in renal sympathetic neurotransmission in the mouse kidney. Am J Physiol Renal Physiol. 2012 Oct;303: F1000-5.
  11. Shein SL, Bell MJ, Kochanek PM, Tyler-Kabara EC, Wisniewski SR, Feldman K, Makoroff K, Scribano PV,Berger RP. Risk Factors for Mortality in Children with Abusive Head Trauma. J Pediatrics. 2012 Oct, 161:716-722
  12. Ji J, Kline AE, Amoscato A, Samhan-Arias AK, Sparvero LJ, Tyurin VA, Tyurina YY, Fink B, Manole MD, Puccio AM, Okonkwo DO, Cheng JP, Alexander H, Clark RSB, Kochanek PM, Wipf P, Kagan VE, Bayir H. Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury. Nature Neuroscience. 2012 Oct,15:1407-13.
  13. Stippler M, Ortiz V, Adelson PD, Chang YF, Tyler-Kabara EC, Wisniewski SR, Fink EL, Kochanek PM, Brown SD,Bell MJ. Brain tissue oxygen monitoring after severe traumatic brain injury in children: relationship to outcome and association with other clinical parameters. J Neurosurg Pediatr. 2012 Sep 14. [Epub ahead of print].
  14. Shein SL, Reynolds TQ, Gedela S, Kochanek PM, Bell MJ. Therapeutic Hypothermia for Refractory Status Epilepticus in a Child with Malignant Migrating Partial Seizures of Infancy and SCN1A Mutation: A Case Report.Therapeutic Hypothermia and Temperature Management. 2012 Sept 2: 144-49.
  15. Hemerka JN, Wu X, Dixon CE, Garman RH, Exo JL, Shellington DK, Blasiole B, Vagni VA, Janesko-Feldman K,Xu M, Wisniewski SR, Jenkins LW, Clark RS, Kochanek PM. Severe Brief pressure-controlled hemorrhagic shock after traumatic brain injury exacerbates functional deficits and long-term neuropathological damage in mice. J Neurotrauma. 2012 Aug 10,29:2192-208
  16. Kirk KA, Shoykhet M, Jeong JH, Tyler-Kabara EC, Henderson MJ, Bell MJ, Fink EL. Dysautonomia after pediatric brain injury. Dev Med Child Neurol. 2012 Aug,54:759-64.
  17. Drabek T, Němec J. Anesthetic management of electrophysiological procedures for heart failure. Int Anesthesiol Clin. 2012 Summer,50:22-42.
  18. Au AK, Aneja RK, Bell MJ, Bayir H, Feldman K, Adelson PD, Fink EL, Kochaneck PM, Clark RSB. Cerebrospinal Fluid Levels of High-Mobility Group Box 1 and Cytochrome C Predict Traumatic Outcome after Pediatric Traumatic Brain Injury. J Neuroscience. 2012 Jul 20, 29: 2013-21.
  19. Bonneh-Barkay D, Zagadailov P, Zou H, Niyonkuru C, Figley M, Starkey A, Wang G, Bissel SJ, Wiley CA, Wagner AK. YKL-40 expression in traumatic brain injury: an initial analysis. J Neurotrauma. 2010 Jul,27:1215-23.
  20. Drabek T. Hydrogen sulfide-curiouser and curiouser!*. Crit Care Med. 2012 Jul,40:2255-6.
  21. Kline AE, Olsen AS, Sozda CN, Hoffman AN, Cheng JP. Evaluation of a Combined Treatment Paradigm Consisting of Environmental Enrichment and the 5-HT(1A) Receptor Agonist Buspirone after Experimental  Traumatic Brain Injury. J Neurotrauma. 2012 Jul 1,29:1960-9. 
  22. Kochanek PM, Bramlett H, Dietrich WD, Dixon CE, Hayes RL, Povlishock J, Tortella FC, Wang KK.  A novel multicenter preclinical drug screening and biomarker consortium for experimental traumatic brain injury: operation brain trauma therapy. J Trauma. 2011 Jul,71(1 Suppl):S15-24.
  23. Verrier JD, Jackson TC, Bansal R, Kochanek PM, Puccio AM, Okonkwo DO, Jackson EK. The brain in vivo expresses the 2′,3′-cAMP-adenosine pathway. J Neurochem. 2012 Jul,122:115-25.
  24. Sparevero LJ, Amoscato AA, Dixon CE, Long JB, Kochanek PM, Pitt BR, Bayir H, Kagan VE. Mapping of phospholipids by MALDI imaging (MALDI-MSI): realities and expectations. Chem Phys Lipids. 2012 Jul, 165:545-62.
  25. Olsen AS, Sozda CN, Cheng JP, Hoffman AN, Kline AE. Traumatic Brain Injury-Induced Cognitive and Histological Deficits are Attenuated by Delayed and Chronic Treatment with the 5-HT(1A)-Receptor Agonist Buspirone. J Neurotrauma. 2012 Jul 1, 29:1898-907.
  26. Wagner AK, Hatz LE, Scanlon JM, Niyonkuru C, Miller MA, Ricker JH, Conley YP, Ferrell RE. Association of KIBRA rs17070145 polymorphism and episodic memory in individuals with severe TBI. Brain Inj. 2012;26(13-14):1658-69
  27. Callaway CW.  Endothelial Damage after Cardiac Arrest-“Endotheliitis”.  Resuscitation. 2012 Jun,83:667-8.
  28. Garman RH, Jenkins LW, Switzer RC 3rd, Bauman RA, Tong LC, Swauger PV, Parks SA, Ritzel DV, Dixon CE,Clark RS, Bayir H, Kagan V, Jackson EK, Kochanek PM. Blast exposure in rats with body shielding is characterized primarily by diffuse axonal injury. J Neurotrauma. 2011 Jun,28:947-59.
  29. Huynh N, Kloke J, Gu C, Callaway CW, Guyette FX, Gebhardt K, Alvarez R, Tisherman SA, Rittenberger JC. The effect of hypothermia “dose” on vasopressor requirements and outcome after cardiac arrest. Resuscitation. 2012 Jun 26. [Epub ahead of print] 
  30. Yelleswarapu NK, Tay JK, Fryer WM, Shah MA, Garcia AN, Cheng JP, Kline AE. Elucidating the role of 5-HT(1A) and 5-HT(7) receptors on 8-OH-DPAT-induced behavioral recovery after experimental traumatic brain injury.Neuroscience Letters. 2012 May 2, 515(2):153-6.
  31. Dezfulian C, Alekseyenko A, Dave KR, Ravai AP, Do R, Kim F, Perez-Pinzon MA. Nitrite therapy is neuroprotective and safe in cardiac arrest survivors. Nitric Oxide. 2012 May 15, 26:241-50.
  32. Shin SS, Verstynen T, Pathak S, Jarbo K, Hricik AJ, Maserati M, Beers SR, Puccio AM, Boada FE, Okonkwo DO, Schneider W. High-definition fiber tracking for assessment of neurological deficit in a case of traumatic brain injury: finding, visualizing, and interpreting small sites of damage. J Neurosurg. 2012 May,116:1062-9.
  33. Munoz-Price LS, Dezfulian C, Wyckoff M, Lenchus JD, Rosalsky M, Birnbach DJ, Arheart KL. Effectiveness of stepwise interventions targeted to decrease central catheter-associated bloodstream infections. Crit Care Med. 2012 May;40:1464-9.
  34. Russell KC, Arenth PM, Scanlon JM, Kessler L, Ricker JH. Hemispheric and executive influences on low-level language processing after traumatic brain injury. Brain Inj. 2012 May, 26:984-95.
  35. Wagner AK, Brett CA, McCullough EH, Niyonkuru C, Loucks TL, Dixon CE, Ricker J, Arenth P, Berga SL. Persistent hypogonadism influences estradiol synthesis, cognition and outcome in males after severe TBI.  Brain Inj. 2012;26(10):1226-42.
  36. Beers SR, Wisniewski SR, Garcia-Filion P, Tian Y, Hahner T, Berger RP, Bell MJ, Adelson PD. Validity of a Pediatric Version of the Glasgow Outcome Scale-Extended. J Neurotrauma. 2012 Apr 10, 29: 1126-39.
  37. Carlson JN, Quintero J, Guyette FX, Callaway CW, Menegazzi JJ. Variables Associated with Successful Intubation Attempts Using Video Laryngoscopy: A Preliminary Report in a Helicopter Emergency Medical Service. Prehosp Emerg Care. 2012 Apr,16,:293-8.
  38. Adelson PD, Pineda J, Bell MJ, Abend NS, Berger RP, Giza CC, Hotz G, Wainwright MS. Common Data Elements for Pediatric Traumatic Brain Injury: Recommendations from the Working Group on Demographics and Clinical Assessment. J Neurotrauma. 2012 Mar 1,29:639-53.
  39. Drabek T, Janata A, Jackson EK, End B, Stezoski J, Vagni VA, Janesko-Feldman K, Wilson CD, van Rooijen N,Tisherman SA, Kochanek PM. Microglial depletion using intrahippocampal injection of liposome-encapsulated clodronate in prolonged hypothermic cardiac arrest in rats. Resuscitation. 2012 Apr;83(4):517-26.
  40. Empey PE, Miller TM, Philbrick AH, Melick J, Kochanek PM, Poloyac SM. Mild hypothermia decreases fentanyl and midazolam steady-state clearance in a rat model of cardiac arrest. Crit Care Med. 2012 Apr,40:1221-8.
  41. Drabek T, Janata A, Jackson EK, End B, Stezoski J, Vagni VA, Janesko-Feldman K, Wilson CD, van Rooijen N,Tisherman SA, Kochanek PM. Microglial depletion using intrahippocampal injection of liposome-encapsulated clodronate in prolonged hypothermic cardiac arrest in rats. Resuscitation. 2012 Apr,83:517-26.
  42. Fink EL, Panigrahy A, Clark RS, Fitz CR, Landsittel D, Kochanek PM, Zuccoli G. Regional Brain Injury on Conventional and Diffusion Weighted MRI is Associated with Outcome After Pediatric Cardiac Arrest. Neurocrit Care. 2012 Apr 26. [Epub ahead of print] 
  43. Salonia R, Bell MJ, Kochanek PM, Berger RP. The Utility of Near Infrared Spectroscopy in Detecting Intracranial Hemorrhage in Children. J Neurotrauma. 2012 Apr 10,29:1047-53.
  44. Shoykhet M, Simons DJ, Alexander H, Holser C, Kochanek PM, Clark RSB. Thalamocortical Dysfunction and Thalamic Injury after Asphyxial Cardiac Arrest in Developing Rats. J Neuroscience. 2012 Apr 4, 32:4972-81.
  45. Tisherman SA.  Rescue therapies in the surgical patient.  Surg Clin North Am. 2012 Apr;92(2):433-9.
  46. Stiell IG, Brown SP, Christenson J, Cheskes S, Nichol G, Powell J, Bigham B, Morrison LJ, Larsen J, Hess E, Vaillancourt C, Davis DP, Callaway CW; the Resuscitation Outcomes Consortium (ROC) Investigators. What is the role of chest compression depth during out-of-hospital cardiac arrest resuscitation? Crit Care Med. 2012 Apr,40:1192-1198.
  47. Berger RP, Beers SR, Papa L, Bell M. Common Data Elements for Pediatric Traumatic Brain Injury: Recommendations from the Biospecimens and Biomarkers Workgroup. J Neurotrauma. 2012 Mar 1,29:672-7.
  48. Ji J, Tyurina YY, Tang M, Feng W, Stolz DB, Clark R, Meaney D, Kochanek PM, Kagan VE, Bayir H.  Mitochondrial Injury after Mechanical Stretch of Cortical Neurons in vitro: Biomarkers of Apoptosis and Selective Peroxidation of Anionic Phospholipids.  J Neurotrauma. 2012 Mar 20;29(5):776-88.
  49. Ji J, Tyurina YY, Tang M, Feng W, Stolz DB, Clark RSB, Meaney DF, Kochanek PM, Kagan VE, Bayir H.Mitochondrial Injury after Mechanical Stretch of Cortical Neurons in vitro: Biomarkers of Apoptosis and Selective Peroxidation of Anionic Phospolipids. J Neurotrauma. 2012 Mar 20,29:776-88.
  50. Manole MD, Kochanek PM, Foley LM, Hitchens TK, Bayir H, Alexander H, Garman R, Ma L, Hsia CJC, HO C, Clark RSB. Polynitroxyl albumin and albumin therapy after pediatric asphyxia cardiac arrest: effects on cerebral blood flow and neurologic outcome. J Cerebral Blood Flow & Metabolism. 2012 Mar, 32:560-9.
  51. Newell E, Bell MJ.  Infections and brain injuries: Beginning to understand the association*.  Pediatr Crit Care Med. 2012 Mar;13(2):222-3.
  52. Shin SS, Bray ER, Dixon CE. Effects of Nicotine Administration on Striatal Dopamine Signaling after Traumatic Brain Injury. J  Neurotrauma. 2012 Mar 20,29:843-50.
  53. Tisherman SA.  Spontaneous cooling and rewarming after cardiac arrest may not be therapeutic.  Resuscitation. 2012 Mar;83(3):283-4.
  54. Wagner AK, Zitelli KT. A Rehabilomics focused perspective on molecular mechanisms underlying neurological injury, complications, and recovery after severe TBI. Pathophysiology. 2012 Mar 21. [Epub ahead of print]
  55. Fink EL, Kochanek PM, Clark RS, Bell MJ: Fever control and application of hypothermia using intravenous cold saline. Pediatr Crit Care Med. 2012 Jan,13:80-4.
  56. Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents–second edition.  Kochanek PM, Carney N, Adelson PD, Ashwal S, Bell MJ, Bratton S, Carson S, Chesnut RM, Ghajar J, Goldstein B, Grant GA, Kissoon N, Peterson K, Selden NR, Tasker RC, Tong KA, Vavilala MS, Wainwright MS, Warden CR; American Academy of Pediatrics-Section on Neurological Surgery; American Association of Neurological Surgeons/Congress of Neurological Surgeons; Child Neurology Society; European Society of Pediatric and Neonatal Intensive Care; Neurocritical Care Society; Pediatric Neurocritical Care Research Group; Society of Critical Care Medicine; Paediatric Intensive Care Society UK; Society for Neuroscience in Anesthesiology and Critical Care; World Federation of Pediatric Intensive and Critical Care Societies.  Pediatr Crit Care Med. 2012 Jan, 13 Suppl 1:S1-82.
  57. Rittenberger JC, Popescu A, Brenner RP, Guyette FX, Callaway CW. Frequency and Timing of Nonconvulsive Status Epilepticus in Comatose Post-Cardiac Arrest Subjects Treated with Hypothermia. Neurocrit Care. 2012 Feb;16(1):114-22.
  58. Machi MS, Staum M, Callaway CW, Moore C, Jeong K, Suyama J, Patterson PD, Hostler D. The Relationship Between Shift Work, Sleep, and Cognition in Career Emergency Physicians. Acad Emerg Med. 2012 Jan, 19:85-91.
  59. Malakouti A, Sookplung P, Siriussawakul A, Philip S, Bailey N, Brown M, Farver K, Zimmerman JJ, Bell MJ, Vavilala MS: Nutrition support and deficiencies in children with severe traumatic brain injury. Pediatr Crit Care Med. 2012 Jan,13:e18-24.
  60. Mills PH, Hitchens TK, Foley LM, Link T, Ye Q, Weiss CR, Thompson JD, Gilson WD, Arepally A, Melick JA,Kochanek PM, Ho C, Bulte JW, Ahrens ET. Automated detection and characterization of SPIO-labeled cells and capsules using magnetic field perturbations. Magn Reson Med. 2012 Jan;67(1):278-89.
  61. Patterson PD, Weaver MD, Frank RC, Warner CW, Martin-Gill C, Guyette FX, Fairbanks RJ, Hubble MW, Songer TJ, Callaway CW, Kelsey SF, Hostler D. Association between poor sleep, fatigue, and safety outcomes in emergency medical services providers. Prehosp Emerg Care. 2012 Jan,16:86-97. 
  62. Smith RL, Lin JC, Adelson PD, Kochanek PM, Fink EL, Wisniewski SR, Bayir H, Tyler-Kabara EC, Clark RS, Brown SD, Bell MJ. Relationship between hyperglycemia and outcome in children with severe traumatic brain injury. Pediatr Crit Care Med. 2012 Jan,13:85-91.
2011
  1. Adelson PD, Srinivas R, Chang Y, Bell M, Kochanek PM. Cerebrovascular response in children following severe traumatic brain injury. Childs Nerv Syst. 2011 Sep; 27(9):1465-76.
  2. Atkinson J, Kapralov AA, Yanamala N, Tyurina YY, Amoscato AA, Pearce L, Peterson J, Huang Z, Jiang J, Samhan-Arias AK, Maeda A, Feng W, Wasserloos K, Belikova NA, Tyurin VA, Wang H, Fletcher J, Wang Y, Vlasova II, Klein-Seetharaman J, Stoyanovsky DA, Bayîr H, Pitt BR, Epperly MW, Greenberger JS, Kagan VE. A mitochondria-targeted inhibitor of cytochrome c peroxidase mitigates radiation-induced death. Nat Commun. 2011 Oct 11;2:497. doi: 10.1038/ncomms1499.
  3. Au AK, Carcillo JA, Clark RS, Bell MJ: Brain injuries and neurological system failure are the most common proximate causes of death in children admitted to a pediatric intensive care unit. Pediatr Crit Care Med. 2011 Sep;12(5):566-71.
  4. Bales JW, Yan HQ, Ma X, Li Y, Samarasinghe R, Dixon CE: The dopamine and cAMP regulated phosphoprotein, 32kDa (DARPP-32) signaling pathway: A novel therapeutic target in traumatic brain injury. Exp Neurol. 2011  Jun;(2):300-7.
  5. Baltagi S, Fink EL, Bell MJ. Therapeutic hypothermia: Ready … fire … aim? How small feasibility studies can inform large efficacy trials. Pediatr Crit Care Med. 2011 May;12(3):370-1.
  6. Becker LB, Aufderheide TP, Geocadin RG, Callaway CW, Lazar RM, Donnino MW, Nadkarni VM, Abella BS, Adrie C, Berg RA, Merchant RM, O’Connor RE, Meltzer DO, Holm MB, Longstreth WT, Halperin HR; American Heart Association Emergency Cardiovascular Care Committee; Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation. Primary outcomes for resuscitation science studies: a consensus statement from the American Heart Association. Circulation. 2011 Nov 8;124(19):2158-77.
  7. Belikova NA, Glumac AL, Kapralova V, Cheikhi A, Tyurina YY, Vagni VA, Kochanek PM, Kagan VE, Bayir H.  A high-throughput screening assay of ascorbate in brain samples.  J Neurosci Methods. 2011 Sep 30;201(1):185-90.
  8. Berger RP.  Predicting outcome after severe pediatric traumatic brain injury: making progress one baby step at a time.  Pediatr Crit Care Med. 2011 May;12(3):362-4.
  9. Berger RP, Fromkin JB, Stutz H, Makoroff K, Scribano PV, Feldman K, Tu LC, Fabio A.  Abusive Head Trauma During a Time of Increased Unemployment: A Multicenter Analysis.  Pediatrics. 2011 Oct;128(4):637-43.
  10. Berger RP, Houle JF, Hayes RL, Wang KK, Mondello S, Bell MJ. Translating biomarkers research to clinical care: applications and issues for rehabilomics. PM R. 2011 Jun;3(6 Suppl):S31-8.
  11. Bulger EM, May S, Kerby JD, Emerson S, Stiell IG, Schreiber MA, Brasel KJ, Tisherman SA, Coimbra R, Rizoli S, Minei JP, Hata JS, Sopko G, Evans DC, Hoyt DB: Out-of-hospital Hypertonic Resuscitation After Traumatic Hypovolemic Shock: A Randomized, Placebo Controlled Trial. Ann Surg. 2011 Mar;253(3):431-441.
  12. Callaway CW: Refining the use of therapeutic hypothermia after cardiac arrest. Crit Care Med. 2011 Jan;39(1):201-2.
  13. Darrah SH, Chuang J, Mohler LM, Chen X, Cummings EE, Burnett T, Reyes-Littaua MC, Galang GN, Wagner AK: Dilantin Therapy in an Experimental Model of Traumatic Brain Injury: Effects of Limited versus Daily Treatment on Neurological and Behavioral Recovery. J Neurotrauma. 2011 Jan;28(1):43-55.
  14. de Witt BW, Ehrenberg KM, McAloon RL, Panos AH, Shaw KE, Raghavan PV, Skidmore ER, Kline AE: Abbreviated Environmental Enrichment Enhances Neurobehavioral Recovery Comparably to Continuous Exposure After Traumatic Brain Injury. Neurorehabil Neural Repair. 2011 May;25(4):343-50.
  15. Drabek T, Kochanek PM, Stezoski J, Wu X, Bayir H, Morhard RC, Stezoski SW, Tisherman SA: Intravenous hydrogen sulfide does not induce hypothermia or improve survival from hemorrhagic shock in pigs. Shock. 2011 Jan;35(1):67-73.
  16. Duffy SO, Squires J, Fromkin JB, Berger RP: Use of skeletal surveys to evaluate for physical abuse: analysis of 703 consecutive skeletal surveys. Pediatrics. 2011 Jan;127(1):e47-52.
  17. Exo J, Kochanek PM, Adelson PD, Greene S, Clark RS, Bayir H, Wisniewski SR, Bell MJ: Intracranial pressure-monitoring systems in children with traumatic brain injury: Combining therapeutic and diagnostic tools. Pediatr Crit Care Med. 2011 Sep;12(5):560-5.
  18. Garcia AN, Shah MA, Dixon CE, Wagner AK, Kline AE. Biologic and plastic effects of experimental traumatic brain injury treatment paradigms and their relevance to clinical rehabilitation. PM R. 2011 Jun;3(6 Suppl):S18-27.
  19. Garman RH, Jenkins LW, Switzer Iii RC, Bauman RA, Tong LC, Swauger PV, Parks S, Ritzel DV, Dixon CE, Clark R, Bayir H, Kagan V, Jackson E, Kochanek PM: Blast exposure in rats with body shielding is characterized by diffuse axonal injury. J Neurotrauma. 2011 Jun; 28(6):947-59.
  20. Joffe AR, Carcillo J, Anton N, Decaen A, Han YY, Bell MJ, Maffei FA, Sullivan J, Thomas J, Garcia-Guerra G. Donation after cardiocirculatory death: a call for a moratorium pending full public disclosure and fully informed consent. Philos Ethics Humanit Med. 2011 Dec 29;6(1):17.
  21. Kochanek PM. Mass critical care for children: implications for adult critical care. Crit Care Med. 2011 Dec;39(12):2783.
  22. Kochanek PM, Bramlett H, Dietrich WD, Dixon CE, Hayes RL, Povlishock J, Tortella FC, Wang KK.  A novel multicenter preclinical drug screening and biomarker consortium for experimental traumatic brain injury: operation brain trauma therapy.    J Trauma. 2011 Jul;71(1 Suppl):S15-24.
  23. Kochanek PM, Kissoon N: Pediatric Critical Care Medicine: Re-tooling to accommodate growth and success while preserving excellence. Pediatr Crit Care Med. 2011 Jan;12(1):1.
  24. Manole MD, Kochanek PM, Clark RS.  “Lost in translation?” Noninvasive cerebral monitoring after cardiac arrest.  Crit Care Med. 2011 Oct;39(10):2379-80.
  25. Manole MD, Tehranian-Depasquale R, Du L, Bayır H, Kochanek PM, Clark RS.  Unmasking Sex-Based Disparity in Neuronal Metabolism.  Curr Pharm Des. 2011 17:3854-3860.]
  26. Martin-Gill C, Dilger CP, Guyette FX, Rittenberger JC, Callaway CW. Regional Impact of Cardiac Arrest Center Criteria on Out-of-Hospital Transportation Practices. Prehosp Emerg Care. 2011  Jul-Sep;15(3):381-7.
  27. Matter AM, Folweiler KA, Curatolo LM, Kline AE: Temporal Effects of Environmental Enrichment-Mediated Functional Improvement After Experimental Traumatic Brain Injury in Rats. Neurorehabil Neural Repair. 2011 Jul;25(6):558-64.
  28. Metter RB, Rittenberger JC, Guyette FX, Callaway CW. Association between a quantitative CT scan measure of brain edema and outcome after cardiac arrest. Resuscitation. 2011 Sep;82(9):1180-5.
  29. Moler FW, Donaldson AE, Meert K, Brilli RJ, Nadkarni V, Shaffner DH, Schleien CL, Clark RS, Dalton HJ, Statler K, Tieves KS, Hackbarth R, Pretzlaff R, van der Jagt EW, Pineda J, Hernan L, Dean JM; Pediatric Emergency Care Applied Research Network: Multicenter cohort study of out-of-hospital pediatric cardiac arrest. Crit Care Med. 2011 Jan;39(1):141-9.
  30. Morley J, Beauchamp G, Suyama J, Guyette FX, Reis SE, Callaway CW, Hostler D. Cognitive function following treadmill exercise in thermal protective clothing. Eur J Appl Physiol. 2011 Sep 3. [Epub ahead of print]
  31. Reinier K, Thomas E, Andrusiek DL, Aufderheide TP, Brooks SC, Callaway CW, Pepe PE, Rea TD, Schmicker RH, Vaillancourt C, Chugh SS. Socioeconomic status and incidence of sudden cardiac arrest. CMAJ. 2011 Oct 18;183(15):1705-12
  32. Rittenberger JC, Callaway CW. Muddy Waters: Hypothermia Does Not Work? Resuscitation. 2011 Sep;82(9):1120-1.
  33. Rittenberger JC, Raina K, Holm MB, Kim YJ, Callaway CW. Association between Cerebral Performance Category, Modified Rankin Scale, and discharge disposition after cardiac arrest. Resuscitation. 2011 Aug;82(8):1036-40.
  34. Rittenberger JC, Tisherman SA, Holm MB, Guyette FX, Callaway CW.  An early, novel illness severity score to predict outcome after cardiac arrest.  Resuscitation. 2011 Nov;82(11):1399-404.
  35. Shellington DK, Du L, Wu X, Exo J, Vagni V, Ma L, Janesko-Feldman K, Clark RS, Bayir H, Dixon CE, Jenkins LW, Hsia CJ, Kochanek PM: Polynitroxylated pegylated hemoglobin: A novel neuroprotective hemoglobin for acute volume-limited fluid resuscitation after combined traumatic brain injury and hemorrhagic hypotension in mice Crit Care Med. 2011 Mar;39(3):494-505.
  36. Shin SS, Bray ER, Zhang CQ, Dixon CE: Traumatic brain injury reduces striatal tyrosine hydroxylase activity and potassium-evoked dopamine release in rats. Brain Res. 2011 Jan 19;1369:208-15.
  37. Shin SS, Dixon CE. Oral fish oil restores striatal dopamine release after traumatic brain injury. Neurosci Lett. 2011 Jun 8;496(3):168-71.
  38. Singbartl K, Murugan R, Kaynar AM, Crippen DW, Tisherman SA, Shutterly K, Stuart SA, Simmons R, Darby JM. Intensivist-Led Management of Brain-Dead Donors Is Associated with an Increase in Organ Recovery for Transplantation. Am J Transplant. 2011 Jul;11(7):1517-21.
  39. Smith CM, Adelson PD, Chang YF, Brown SD, Kochanek PM, Clark RS, Bayir H, Hinchberger J, Bell MJ: Brain-systemic temperature gradient is temperature-dependent in children with severe traumatic brain injury. Pediatr Crit Care Med. 2011 Jul;12(4):449-54.
  40. Smith CM, Chen Y, Sullivan ML, Kochanek PM, Clark RS: Autophagy in Acute Brain Injury: Feast, Famine, or Folly? Neurobiol Dis.  2011 Jul;43(1):52-9.
  41. Stoyanovsky DA, Huang Z, Jiang J, Belikova NA, Tyurin V, Epperly MW, Greenberger JS, Bayir H, Kagan VE.  A manganese-porphyrin complex decomposes H(2)O(2), inhibits apoptosis, and acts as a radiation mitigator in vivo.  ACS Med Chem Lett. 2011 Nov 10;2(11):814-817.
  42. Suffoletto B, Frisch A, Prabhu A, Kristan J, Guyette FX, Callaway CW. Prediction of Serious Infection during Prehospital Emergency Care. Prehosp Emerg Care. 2011  Jul-Sep;15(3):325-30.
  43. Tisherman SA, Ivy ME, Frangos SG, Kirton OC: Acute care surgery survey: opinions of surgeons about a new training paradigm. Arch Surg. 2011 Jan;146(1):101-6.
  44. Verrier JD, Exo JL, Jackson TC, Ren J, Gillespie DG, Dubey RK, Kochanek PM, Jackson EK. Expression of the 2′,3′-cAMP-adenosine pathway in astrocytes and microglia.  J Neurochem. 2011 Sep;118(6):979-87.
  45. Wagner AK. Conclusions on biologics in rehabilitation research and clinical care. PM R. 2011 Jun;3(6 Suppl):S158.
  46. Wagner AK. Rehabilomics: a conceptual framework to drive biologics research. PM R. 2011 Jun;3(6 Suppl):S28-30.
  47. Wagner AK, Amin KB, Niyonkuru C, Postal BA, McCullough EH, Ozawa H, Dixon CE, Bayir H, Clark RS, Kochanek PM, Fabio A: CSF Bcl-2 and cytochrome C temporal profiles in outcome prediction for adults with severe TBI. J Cereb Blood Flow Metab. 2011 Sep;31(9):1886-96.
  48. Wagner AK, McCullough EH, Niyonkuru C, Ozawa H, Loucks TL, Dobos JA, Brett CA, Santarsieri M, Dixon CE, Berga SL, Fabio A. Acute serum hormone levels: characterization and prognosis after severe traumatic brain injury. J Neurotrauma. 2011 Jun;28(6):871-88.
2010
  1. Abdulkadir AA, Kimimasa T, Bell MJ, Macpherson TA, Keller BB, Yanowitz TD: Placental Inflammation and Fetal Hemodynamics in a Rat Model of Chorioamnionitis. Pediatr Res. 2010 Dec;68(6):513-8.
  2. Au AK, Bayir H, Kochanek PM, Clark RS: Evaluation of autophagy using mouse models of brain injury. Biochim Biophys Acta. 2010 Oct;1802(10):918-23
  3. Au A, Bell MJ: Prevention of hospital-acquired hyponatremia in children: Are hypotonic solutions safe? Pediatr Crit Care Med. 2010 Jul;11(4):528-9
  4. Bales JW, Ma X, Yan HQ, Jenkins LW, Dixon CE: Regional calcineurin subunit B isoform expression in rat hippocampus following a traumatic brain injury. Brain Res. 2010 Oct 28;1358:211-20
  5. Bales JW, Ma X, Yan HQ, Jenkins LW, Dixon CE:  Expression of protein phosphatase 2B (calcineurin) subunit A isoforms in rat hippocampus after traumatic brain injury.  J Neurotrauma. 2010 Jan;27(1):109-20
  6. Baltagi SA, Shoykhet M, Felmet K, Kochanek PM, Bell MJ:  Neurological sequelae of pH1N1 influenza in children: A case series observed during a pandemic*.  Pediatr Crit Care Med. 2010 Mar;11(2):179-84
  7. Berger RP, Bazaco MC, Wagner AK, Kochanek PM, Fabio A: Trajectory analysis of serum biomarker concentrations facilitates outcome prediction after pediatric traumatic and hypoxemic brain injury. Dev Neurosci. 2010;32(5-6):396-405
  8. Bonneh-Barkay D, Zagadailov P, Zou H, Niyonkuru C, Figley M, Starkey A, Wang G, Bissel SJ, Wiley CA, Wagner AK: YKL-40 Expression in Traumatic Brain Injury: An Initial Analysis. J Neurotrauma. 2010 Jul 12.Jul;27(7):1215-23.
  9. Bulger EM, May S, Brasel KJ, Schreiber M, Kerby JD, Tisherman SA, Newgard C, Slutsky A, Coimbra R, Emerson S, Minei JP, Bardarson B, Kudenchuk P, Baker A, Christenson J, Idris A, Davis D, Fabian TC, Aufderheide TP, Callaway C, Williams C, Banek J, Vaillancourt C, van Heest R, Sopko G, Hata JS, Hoyt DB; ROC Investigators: Out-of-hospital hypertonic resuscitation following severe traumatic brain injury: a randomized controlled trial. JAMA. 2010 Oct 6;304(13):1455-64.
  10. Callaway CW, Schmicker R, Kampmeyer M, Powell J, Rea TD, Daya MR, Aufderheide TP, Davis DP, Rittenberger JC, Idris AH, Nichol G; The Resuscitation Outcomes Consortium (ROC) Investigators:  Receiving hospital characteristics associated with survival after out-of-hospital cardiac arrest.  Resuscitation. 2010 May;81(5):524-9.
  11. D’Onofrio G, Jauch E, Jagoda A, Allen MH, Anglin D, Barsan WG, Berger RP, Bobrow BJ, Boudreaux ED, Bushnell C, Chan YF, Currier G, Eggly S, Ichord R, Larkin GL, Laskowitz D, Neumar RW, Newman-Toker DE, Quinn J, Shear K, Todd KH, Zatzick D; Roundtable External Participants and Roundtable Steering Committee and Federal Participants: NIH Roundtable on Opportunities to Advance Research on Neurologic and Psychiatric Emergencies. Ann Emerg Med. 2010 Nov;56(5):551-64
  12. Fink EL, Clark RS, Kochanek PM, Bell MJ, Watson RS:  A tertiary care center’s experience with therapeutic hypothermia after pediatric cardiac arrest*.  Pediatr Crit Care Med. 2010 Jan;11(1):66-74.
  13. Fink EL, Kochanek PM, Clark RS, Bell MJ:  How I Cool Children in Neurocritical Care. Neurocrit Care. 2010 Jun;12(3):414-20..
  14. Hartke A, Mumma BE, Rittenberger JC, Callaway CW, Guyette FX: Incidence of re-arrest and critical events during prolonged transport of post-cardiac arrest patients. Resuscitation. 2010 Aug;81(8):938-42
  15. Haselkorn ML, Shellington D, Jackson E, Vagni VA, Janesko KL, Dubey RK, Gillespie DG, Cheng D, Bell MJ, Jenkins LW, Homanics GE, Schnermann J, Kochanek PM:  Adenosine A1 Receptor Activation as a Brake on the Microglial Response after Experimental Traumatic Brain Injury in Mice. J Neurotrauma. 2010 May;27(5):901-10.
  16. Hoh NZ, Wagner AK, Alexander SA, Clark RB, Beers SR, Okonkwo DO, Ren D, Conley YP: BCL2 genotypes: functional and neurobehavioral outcomes after severe traumatic brain injury. J Neurotrauma. 2010 Aug;27(8):1413-27
  17. Hostler D, Thomas EG, Emerson SS, Christenson J, Stiell IG, Rittenberger JC, Gorman KR, Bigham BL, Callaway CW, Vilke GM, Beaudoin T, Cheskes S, Craig A, Davis DP, Reed A, Idris A, Nichol G; Resuscitation Outcomes Consortium Investigators: Increased survival after EMS witnessed cardiac arrest. Observations from the Resuscitation Outcomes Consortium (ROC) Epistry-Cardiac arrest. Resuscitation. 2010 Jul;81(7):826-30.
  18. Hostler D, Zhou J, Tortorici MA, Bies RR, Rittenberger JC, Empey PE, Kochanek PM, Callaway CW, Poloyac SM:  Mild Hypothermia Alters Midazolam Pharmacokinetics in Normal Healthy Volunteers.Drug Metab Dispos. 2010 May;38(5):781-8.
  19. Janata A, Weihs W, Schratter A, Bayegan K, Holzer M, Frossard M, Sipos W, Springler G, Schmidt P, Sterz F, Losert UM, Laggner AN, Kochanek PM, Behringer W: Cold aortic flush and chest compressions enable good neurologic outcome after 15 minutes of ventricular fibrillation in cardiac arrest in pigs. Crit Care Med. 2010 Aug;38(8):1637-43.
  20. King C, Robinson T, Dixon CE, Rao GR, Larnard DJ, Nemoto EM: Brain Temperature Profiles during Epidural Cooling with the Chillerpad in a Monkey Model of Traumatic Brain Injury. J Neurotrauma. 2010 Oct;27(10):1895-903.
  21. Kline AE, McAloon RL, Henderson KA, Bansal UK, Ganti BM, Ahmed RH, Gibbs RB, Sozda CN: Evaluation of a combined therapeutic regimen of 8-OH-DPAT and environmental enrichment after experimental traumatic brain injury. J Neurotrauma. 2010 Nov;27(11):2021-32
  22. Kochanek PM, Bayir H: Titrating oxygen during and after cardiopulmonary resuscitation. JAMA. 2010 Jun 2;303(21):2190-1.
  23. Kochanek PM, Bell MJ, Bayır H. Quo vadis 2010? – carpe diem: challenges and opportunities in pediatric traumatic brain injury. Dev Neurosci. 2010;32(5-6):335-342.
  24. Mehta A, Kochanek PM, Tyler-Kabara E, Adelson PD, Wisniewski SR, Berger RP, Sidoni MD, Bell RL, Clark RS, Bell MJ: Relationship of intracranial pressure and cerebral perfusion pressure with outcome in young children after severe traumatic brain injury. Dev Neurosci. 2010;32(5-6):413-9
  25. Miller MA, Conley Y, Scanlon JM, Ren D, Ilyas Kamboh M, Niyonkuru C, Wagner AK: APOE genetic associations with seizure development after severe traumatic brain injury. Brain Inj. 2010;24(12):1468-77
  26. Nichol G, Aufderheide TP, Eigel B, Neumar RW, Lurie KG, Bufalino VJ, Callaway CW, Menon V, Bass RR, Abella BS, Sayre M, Dougherty CM, Racht EM, Kleinman ME, O’Connor RE, Reilly JP, Ossmann EW, Peterson E; on behalf of the American Heart Association Emergency Cardiovascular Care Committee; Council on Arteriosclerosis, Thrombosis, and Vascular Biology; Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation; Council on Cardiovascular Nursi:  Regional Systems of Care for Out-of-Hospital Cardiac Arrest. A Policy Statement From the American Heart Association.  Circulation. 2010 Feb 9;121(5):709-729.
  27. Nolan JP, Neumar RW, Adrie C, Aibiki M, Berg RA, Bbttiger BW, Callaway C, Clark RS, Geocadin RG, Jauch EC, Kern KB, Laurent I, Longstreth WT, Merchant RM, Morley P, Morrison LJ, Nadkarni V, Peberdy MA, Rivers EP, Rodriguez-Nunez A, Sellke FW, Spaulding C, Sunde K, Vanden Hoek T; International Liaison Committee on Resuscitation; Emergency Cardiovascular Care Committee, American Heart Association; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiopulmonary, Perioperative, and Critical Care; Council on Clinical Cardiology; Council on Stroke: Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication: a scientific statement from the International Liaison Committee on Resuscitation; the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; the Council on Stroke (Part II). Int Emerg Nurs. 2010 Jan;18(1):8-28.
  28. Ochalski PG, Fellows-Mayle W, Hsieh LB, Srinivas R, Okonkwo DO, Dixon CE, Adelson PD:  Flumazenil administration attenuates cognitive impairment in immature rats following controlled cortical impact.  J Neurotrauma. 2010 March:27(3): 647-651.
  29. Rittenberger JC, Sangl J, Wheeler M, Guyette FX, Callaway CW: Association between clinical examination and outcome after cardiac arrest. Resuscitation. 2010 Sep;81(9):1128-1132.
  30. Salcido DD, Stephenson AM, Condle JP, Callaway CW, Menegazzi JJ: Incidence of rearrest after return of spontaneous circulation in out-of-hospital cardiac arrest. Prehosp Emerg Care. 2010 Oct-Dec;14(4):413-8.
  31. Salonia R, Empey P, Poloyac SM, Wisniewski SR, Klamerus M, Ozawa H, Wagner AK, Ruppel R, Bell MJ, Janesko KL, Adelson PD, Clark R, Kochanek PM: Endothelin-1 is Increased in Cerebrospinal Fluid and Associated with Unfavorable Outcomes in Children after Severe Traumatic Brain Injury. J Neurotrauma. 2010 Oct;27(10):1819-25.
  32. Sanchez de Toledo J, Bell MJ: Complications of hypothermia: interpreting ‘serious,’ ‘adverse,’ and ‘events’ in clinical trials. Pediatr Crit Care Med. 2010 May;11(3):439-41
  33. Sarnaik A, Conley YP, Okonkwo DO, Barr T, Fink EL, Szabo C, Kochanek PM, Clark R:  Influence of PARP-1 Polymorphisms in Patients after Traumatic Brain Injury.  J Neurotrauma. 2010 March:27(3):465-471
  34. Singleton RH, Yan HQ, Fellows-Mayle W, Dixon CE: Resveratrol attenuates behavioral impairments and reduces cortical and hippocampal loss in a rat controlled cortical impact model of traumatic brain injury. J Neurotrauma. 2010 Jun;27(6):1091-9.
  35. Sozda CN, Hoffman AN, Olsen AS, Cheng JP, Zafonte R, Kline AE:  Empirical comparison of typical and atypical environmental enrichment paradigms on functional and histological outcome after experimental traumatic brain injury.J Neurotrauma. 2010 Jun;27(6):1047-57.
  36. Sparvero LJ, Amoscato AA, Kochanek PM, Pitt BR, Kagan VE, Bayir H: Mass-spectrometry based oxidative lipidomics and lipid imaging: applications in traumatic brain injury. J Neurochem. 2010 Dec;115(6):1322-36
  37. Stoyanovsky DA, Kapralov A, Huang Z, Maeda A, Osipov A, Hsia CJ, Ma L, Kochanek PM, Bayr H, Kagan VE: Unusual peroxidase activity of polynitroxylated pegylated hemoglobin: Elimination of H(2)O(2) coupled with intramolecular oxidation of nitroxides. Biochem Biophys Res Commun. 2010 Aug 20;399(2):139-143.
  38. Su E, Bell MJ, Wisniewski SR, Adelson PD, Janesko-Feldman KL, Salonia R, Clark RS, Kochanek PM, Kagan VE, Bayır H: α-Synuclein Levels Are Elevated in Cerebrospinal Fluid following Traumatic Brain Injury in Infants and Children: The Effect of Therapeutic Hypothermia. Dev Neurosci. 2010;32(5-6):385-95
  39. Su E, Shoykhet M, Bell MJ: Severe hypernatremia in a hospitalized child: munchausen by proxy. Pediatr Neurol. 2010 Oct;43(4):270-3.
  40. Tang M, Alexander H, Clark RS, Kochanek PM, Kagan VE, Bayır H:  Minocycline reduces neuronal death and attenuates microglial response after pediatric asphyxial cardiac arrest.  J Cereb Blood Flow Metab. 2010 Jan;30(1):119-29
  41. Tisherman SA: Cannabinoids after cardiac arrest: should your brain be on drugs? Crit Care Med. 2010 Dec;38(12):2409-10
  42. Tisherman SA: Is fibrinogen the answer to coagulopathy after massive transfusions? Crit Care. 2010 2010;14(3):154
  43. Tisherman SA: The yin and yang of hypothermia in trauma. J Intensive Care Med. 2010 Jul;25(4):240-2.
  44. Tisherman SA: When it comes to hypothermia and trauma: kids are really little adults. Pediatr Crit Care Med. 2010 Mar;11(2):301-2
  45. Tisherman SA, Drabek T: Can an ice cream headache save your life? Crit Care Med. 2010 Mar;38(3):1006-7.
  46. Tress EE, Kochanek PM, Saladino RA, Manole MD: Cardiac arrest in children. J Emerg Trauma Shock. 2010 Jul;3(3):267-72.
  47. Tyurin VA, Tyurina YY, Ritov VB, Lysytsya A, Amoscato AA, Kochanek PM, Hamilton R, Dekosky ST, Greenberger JS, Bayir H, Kagan VE:  Oxidative lipidomics of apoptosis: quantitative assessment of phospholipid hydroperoxides in cells and tissues.  Methods Mol Biol. 2010;610:353-74
  48. Vitale MA, Squires J, Zuckerbraun NS, Berger RP:  Evaluation of the Siblings of Physically Abused Children: A Comparison of Child Protective Services Caseworkers and Child Abuse Physicians.Child Maltreat. 2010 May;15(2):144-51.
  49. Wagner AK: The Traumatic Brain Injury Model Systems: a longitudinal database, research, collaboration and knowledge translation. Eur J Phys Rehabil Med. 2010 Dec;46(4):549-56.
  50. Wagner AK, Miller MA, Scanlon J, Ren D, Kochanek PM, Conley YP: Adenosine A1 receptor gene variants associated with post-traumatic seizures after severe TBI. Epilepsy Res. 2010 Aug;90(3):259-72
2009
  1. Abrahamson EE, Ikonomovic MD, Dixon CE, DeKosky ST:  Simvastatin therapy prevents brain trauma-induced increases in beta-amyloid peptide levels.  Ann Neurol. 2009 Sep;66(3):407-14.
  2. Au AK, Bayır H, Kochanek PM, Clark RS:  Evaluation of autophagy using mouse models of brain injury.  Biochim Biophys Acta. 2010 Oct;1802(10):918-23
  3. Berger RP, Richichi R:  Derivation and validation of an equation for adjustment of neuron-specific enolase concentrations in hemolyzed serum.  Pediatr Crit Care Med 2009 Mar;10(2):260-3.
  4. Belikova NA, Glumac A, Rafikov R, Jiang J, Greenberger JS, Kagan VE, Bayir H:  Radioprotection by short-term oxidative preconditioning: role of manganese superoxide dismutase.  FEBS Lett. 2009 Nov 3;583(21):3437-42.
  5. Campbell KA, Squires J, Cook LJ, Berger RP:  Disparities in the medical examination of children in the home of a child with suspected physical abuse.  Child Abuse Negl. 2009 Sep;33(9):612-7.
  6. Christenson J, Andrusiek D, Everson-Stewart S, Kudenchuk P, Hostler D, Powell J, Callaway CW, Bishop D, Vaillancourt C, Davis D, Aufderheide TP, Idris A, Stouffer JA, Stiell I, Berg R; Resuscitation Outcomes Consortium Investigators:  Chest compression fraction determines survival in patients with out-of-hospital ventricular fibrillation.  Circulation. 2009 Sep 29;120(13):1241-7.
  7. Bales JW, Wagner AK, Kline AE, Dixon CE:  Persistent cognitive dysfunction after traumatic brain injury: A dopamine hypothesis.  Neurosci Biobehav Rev. 2009 Jul;33(7):981-1003.
  8. Bayir H, Adelson PD, Wisniewski SR, Shore P, Lai Y, Brown D, Janesko-Feldman KL, Kagan VE, Kochanek PM: Therapeutic hypothermia preserves antioxidant defenses after severe traumatic brain injury in infants and children. Crit Care Med. 2009 Feb;37(2):689-95. Erratum in: Crit Care Med. 2009 Apr;37(4):1536.
  9. Bayir H, Kapralov AA, Jiang J, Huang Z, Tyurina YY, Tyurin VA, Zhao Q, Belikova NA, Vlasova II, Maeda A, Zhu J, Na HM, Mastroberardino PG, Sparvero LJ, Amoscato AA, Chu CT, Greenamyre JT, Kagan VE: Peroxidase mechanism of lipid dependent cross-linking of synuclein with cytochrome c: protection against apoptosis versus delayed oxidative stress in Parkinson’s disease. J Biol Chem. 2009 Jun 5;284(23):15951-69.
  10. Belikova NA, Jiang J, Stoyanovsky DA, Glumac A, Bayir H, Greenberger JS, Kagan VE: Mitochondria-targeted (2-hydroxyamino-vinyl)-triphenyl-phosphonium releases NO() and protects mouse embryonic cells against irradiation-induced apoptosis. FEBS Lett. 2009 Jun 18;583(12):1945-50
  11. Bell MJ, Carpenter J, Au AK, Keating RF, Myseros JS, Yaun A, Weinstein S:  Development of a Pediatric Neurocritical Care Service. Neurocrit Care. 2009;10(1):4-10.
  12. Berger RP, T’asan S, Rand A, Lokshin A, Kochanek P:   Multiplex assessment of serum biomarker concentrations in well-appearing children with inflicted traumatic brain injury.  Pediatr Res. 2009 Jan;65(1):97-102.
  13. Berger R, Richichi R:  Derivation and validation of an equation for adjustment of neuron-specific enolase concentrations in hemolyzed serum.  Pediatr Crit Care Med. 2009 Mar;10(2):260-3.
  14. Chu CT, Plowey ED, Dagda RK, Hickey RW, Cherra SJ 3rd, Clark RS: Autophagy in neurite injury and neurodegeneration: in vitro and in vivo models. Methods Enzymol. 2009;453:217-49.
  15. Dennis AM, Haselkorn ML, Vagni VA, Garman RH, Janesko-Feldman K, Bayir H, Clark RS, Jenkins LW, Dixon CE, Kochanek PM:  Hemorrhagic shock after experimental traumatic brain injury in mice: effect on neuronal death.  J Neurotrauma. 2009 Jun;26(6):889-99.
  16. Dietrich WD, Bullock MR, Kochanek PM: Hypothermic therapies targeting brain and spinal cord injury. Introduction. J Neurotrauma. 2009 Mar;26(3):297-8.
  17. Drabek T, Tisherman SA, Beuke L, Stezoski J, Janesko-Feldman K, Lahoud-Rahme M, Kochanek PM: Deep hypothermia attenuates microglial proliferation independent of neuronal death after prolonged cardiac arrest in rats. Anesth Analg. 2009 Sep;109(3):914-23
  18. Du L, Hickey RW, Bayir H, Watkins SC, Tyurin VA, Guo F, Kochanek PM, Jenkins LW, Ren J, Gibson G, Chu CT, Kagan VE, Clark RS: Starving neurons show sex difference in autophagy. J Biol Chem. 2009 Jan 23;284(4):2383-96.
  19. Exo J, Shellington D, Bayir H, Vagni V, Janesko KL, Ma L, Hsia CJ, Clark R, Jenkins LW, Dixon CE, Kochanek PM: Resuscitation of Traumatic Brain Injury and Hemorrhagic Shock with Polynitroxylated Albumin, Hextend, Hypertonic Saline and Lactated Ringers: Effects on Acute Hemodynamics, Survival, and Neuronal Death in Mice. J Neurotrauma. 2009 Dec;26(12):2403-8.
  20. Foley LM, Hitchens TK, Ho C, Janesko KL, Melick JA, Bayir H, Kochanek PM: Magnetic Resonance Imaging Assessment of Macrophage Accumulation in Mouse Brain after Experimental Traumatic Brain Injury. J Neurotrauma. 2009 Sep;26(9):1509-19.
  21. Hicks SD, Salcido DD, Logue ES, Suffoletto BP, Empey PE, Poloyac SM, Miller DR, Callaway CW, Menegazzi JJ:  Lipid Emulsion Combined with Epinephrine and Vasopressin Does Not Improve Survival in a Swine Model of Bupivacaine-induced Cardiac Arrest.  Anesthesiology. 2009 Jul;111(1):138-46.
  22. Holevar M, Dunham JC, Brautigan R, Clancy TV, Como JJ, Ebert JB, Griffen MM, Hoff WS, Kurek SJ Jr, Talbert SM, Tisherman SA:  Practice management guidelines for timing of tracheostomy: the EAST practice management guidelines work group.  J Trauma. 2009 Oct;67(4):870-4.
  23. Kagan VE, Wipf P, Stoyanovsky D, Greenberger JS, Borisenko G, Belikova NA, Yanamala N, Samhan Arias AK, Tungekar MA, Jiang J, Tyurina YY, Ji J, Klein-Seetharaman J, Pitt BR, Shvedova AA, Bayir H:  Mitochondrial targeting of electron scavenging antioxidants: Regulation of selective oxidation vs random chain reactions.  Adv Drug Deliv Rev. 2009 Nov 30;61(14):1375-85.
  24. Kagan VE, Bayir A, Bayir H, Stoyanovsky D, Borisenko GG, Tyurina YY, Wipf P, Atkinson J, Greenberger JS, Chapkin RS, Belikova NA: Mitochondria-targeted disruptors and inhibitors of cytochrome c/cardiolipin peroxidase complexes: a new strategy in anti-apoptotic drug discovery. Mol Nutr Food Res. 2009 Jan;53(1):104-14. Review.
  25. Kagan VE, Bayir HA, Belikova NA, Kapralov O, Tyurina YY, Tyurin VA, Jiang J, Stoyanovsky DA, Wipf P, Kochanek PM, Greenberger JS, Pitt B, Shvedova AA, Borisenko G: Cytochrome c/cardiolipin relations in mitochondria: a kiss of death. Free Radic Biol Med. 2009 Jun 1;46(11):1439-53.
  26. Kampmeyer M, Callaway C:  Method of cold saline storage for prehospital induced hypothermia.  Prehosp Emerg Care. 2009 Jan-Mar;13(1):81-4
  27. Kapralov A, Vlasova II, Feng W, Maeda A, Walson K, Tyurin VA, Huang Z, Aneja RK, Carcillo J, Bayir H, Kagan VE:  Peroxidase activity of hemoglobin x haptoglobin complexes: covalent aggregation and oxidative stress in plasma and macrophages.  J Biol Chem. 2009 Oct 30;284(44):30395-407.
  28. Kochanek PM, Tasker RC:  Pediatric neurointensive care: 2008 update for the Rogers’ Textbook of Pediatric Intensive Care.  Pediatr Crit Care Med. 2009 Jul;10(4):517-23
  29. Kochanek PM: Bakken Lecture: the brain, the heart, and therapeutic hypothermia. Cleve Clin J Med. 2009 Apr;76 Suppl 2:S8-12.
  30. Kochanek PM, Bauman RA, Long J, Dixon CE, Jenkins LW:  A critical problem begging for new insight and new therapies.  J Neurotrauma. 2009 Jun;26(6):813-4.
  31. Kochanek PM, Drabek T, Tisherman SA: Therapeutic hypothermia: the Safar vision. J Neurotrauma. 2009 Mar;26(3):417-20.
  32. Kochanek PM, Fink EL, Bell MJ, Bayir H, Clark RS: Therapeutic hypothermia: applications in pediatric cardiac arrest. J Neurotrauma. 2009 Mar;26(3):421-7.
  33. Konduru NV, Tyurina YY, Feng W, Basova LV, Belikova NA, Bayir H, Clark K, Rubin M, Stolz D, Vallhov H, Scheynius A, Witasp E, Fadeel B, Kichambare PD, Star A, Kisin ER, Murray AR, Shvedova AA, Kagan VE: Phosphatidylserine targets single-walled carbon nanotubes to professional phagocytes in vitro and in vivo. PLoS ONE. 2009;4(2):e4398.
  34. Lahoud-Rahme MS, Stezoski J, Kochanek PM, Melick J, Tisherman SA, Drabek T: Blood-brain barrier integrity in a rat model of emergency preservation and resuscitation. Resuscitation. 2009 Apr;80(4):484-8.
  35. Manole MD, Kochanek PM, Fink EL, Clark RS:  Postcardiac arrest syndrome: focus on the brain.  Curr Opin Pediatr. 2009 Dec;21(6):745-50.
  36. Manole MD, Foley LM, Hitchens TK, Kochanek PM, Hickey RW, Bayır H, Alexander H, Ho C, Clark RS:  Magnetic resonance imaging assessment of regional cerebral blood flow after asphyxial cardiac arrest in immature rats.  J Cereb Blood Flow Metab. 2009 Jan;29(1):197-205.
  37. Meert KL, Donaldson A, Nadkarni V, Tieves KS, Schleien CL, Brilli RJ, Clark RS, Shaffner DH, Levy F, Statler K, Dalton HJ, van der Jagt EW, Hackbarth R, Pretzlaff R, Hernan L, Dean JM, Moler FW; for the Pediatric Emergency Care Applied Research Network:  Multicenter cohort study of in-hospital pediatric cardiac arrest.  Pediatr Crit Care Med. 2009 Sep;10(5):544-53.
  38. Moler FW, Meert K, Donaldson AE, Nadkarni V, Brilli RJ, Dalton HJ, Clark RS, Shaffner DH, Schleien CL, Statler K, Tieves KS, Hackbarth R, Pretzlaff R, van der Jagt EW, Levy F, Hernan L, Silverstein FS, Dean JM; for the Pediatric Emergency Care Applied Research Network:  In-hospital versus out-of-hospital pediatric cardiac arrest: A multicenter cohort study.  Crit Care Med. 2009 Jul;37(7):2259-67.
  39. Mumma BE, Shellenbarger D, Callaway CW, Katz KD, Guyette FX, Rittenberger JC: Neurologic recovery following cardiac arrest due to carbon monoxide poisoning. Resuscitation. 2009 Dec;80(12):1446-7.
  40. Napolitano LM, Kurek S, Luchette FA, Anderson GL, Bard MR, Bromberg W, Chiu WC, Cipolle MD, Clancy KD, Diebel L, Hoff WS, Hughes KM, Munshi I, Nayduch D, Sandhu R, Yelon JA, Corwin HL, Barie PS, Tisherman SA, Hebert PC; EAST Practice Management Workgroup; American College of Critical Care Medicine (ACCM) Taskforce of the Society of Critical Care Medicine (SCCM):  Clinical practice guideline: red blood cell transfusion in adult trauma and critical care.  J Trauma. 2009 Dec;67(6):1439-42.
  41. Napolitano LM, Kurek S, Luchette FA, Corwin HL, Barie PS, Tisherman SA, Hebert PC, Anderson GL, Bard MR, Bromberg W, Chiu WC, Cipolle MD, Clancy KD, Diebel L, Hoff WS, Hughes KM, Munshi I, Nayduch D, Sandhu R, Yelon JA; American College of Critical Care Medicine of the Society of Critical Care Medicine; Eastern Association for the Surgery of Trauma Practice Management Workgroup:  Clinical practice guideline: red blood cell transfusion in adult trauma and critical care.  Crit Care Med. 2009 Dec;37(12):3124-57.
  42. Newgard CD, Rudser K, Atkins DL, Berg R, Osmond MH, Bulger EM, Davis DP, Schreiber MA, Warden C, Rea TD, Emerson S; ROC Investigators:  The availability and use of out-of-hospital physiologic information to identify high-risk injured children in a multisite, population-based cohort.  Prehosp Emerg Care. 2009 Oct-Dec;13(4):420-31.
  43. Nolan JP, Neumar RW, Adrie C, Aibiki M, Berg RA, Bbttiger BW, Callaway C, Clark RS, Geocadin RG, Jauch EC, Kern KB, Laurent I, Longstreth WT, Merchant RM, Morley P, Morrison LJ, Nadkarni V, Peberdy MA, Rivers EP, Rodriguez-Nunez A, Sellke FW, Spaulding C, Sunde K, Hoek TV:  Post-cardiac arrest syndrome: Epidemiology, pathophysiology, treatment, and prognostication: A scientific statement from the International Liaison Committee on Resuscitation; the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; the Council on Stroke (Part 1).  Int Emerg Nurs. 2009 Oct;17(4):203-25.
  44. Ochalski PG, Okonkwo DO, Bell MJ, Adelson PD: Reversal of sedation with flumazenil in a child after traumatic brain injury. J Neurosurg Pediatr. 2009 Mar;3(3):240-3.
  45. Puccio AM, Hoffman LA, Bayir H, Zullo TG, Michael FR, Darby JM, Alexander SA, Dixon CE, Okonkwo DO, Kochanek PM:  Effect of short periods of normobaric hyperoxia on local brain tissue oxygenation and cerebrospinal fluid oxidative stress markers in severe traumatic brain injury.  J Neurotrauma. 2009 Aug;26(8):1241-9.
  46. Reynolds JC, Callaway CW, El Khoudary SR, Moore CG, Alvarez RJ, Rittenberger JC: Review of A Large Clinical Series: Coronary Angiography Predicts Improved Outcome Following Cardiac Arrest: Propensity-adjusted Analysis. J Intensive Care Med. 2009 May-Jun;24(3):179-86.
  47. Rittenberger JC, Callaway CW: Transport of Patients After Out-of-Hospital Cardiac Arrest: Closest Facility or Most Appropriate Facility? Ann Emerg Med. 2009 Aug;54(2):256-7
  48. Sanchez de Toledo J, Adelson PD, Watson RS, Gaines B, Brown SD, Kochanek PM, Wisniewski SR, Fink E, Bayır H, Clark RS, Bell MJ: Relationship Between Increases in Pancreatic Enzymes and Cerebral Events in Children After Traumatic Brain Injury. Neurocrit Care. 2009 Aug 11. [Epub ahead of print]
  49. Shvedova AA, Kagan VE: Phosphatidylserine targets single-walled carbon nanotubes to professional phagocytes in vitro and in vivo. PLoS ONE. 2009;4(2):e4398
  50. Suffoletto B, Peberdy MA, van der Hoek T, Callaway C:  Body temperature changes are associated with outcomes following in-hospital cardiac arrest and return of spontaneous circulation.  Resuscitation. 2009 Dec;80(12):1365-70.
  51. Tortorici MA, Mu Y, Kochanek PM, Xie W, Poloyac SM: Moderate hypothermia prevents cardiac arrest-mediated suppression of drug metabolism and induction of interleukin-6 in rats. Crit Care Med. 2009 Jan;37(1):263-9.
  52. Tyurin VA, Tyurina YY, Jung MY, Tungekar MA, Wasserloos KJ, Bayır H, Greenberger JS, Kochanek PM, Shvedova AA, Pitt B, Kagan VE: Mass-spectrometric analysis of hydroperoxy- and hydroxy-derivatives of cardiolipin and phosphatidylserine in cells and tissues induced by pro-apoptotic and pro-inflammatory stimuli. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Sep 15;877(26):2863-72.
  53. Wagner AK, Drewencki LL, Chen X, Santos FR, Khan AS, Harun R, Torres GE, Michael AC, Dixon CE: Chronic methylphenidate treatment enhances striatal dopamine neurotransmission after experimental traumatic brain injury. J Neurochem. 2009 Feb;108(4):986-97.
  54. Wagner AK, Sokoloski JE, Chen X, Harun R, Clossin DP, Khan AS, Andes-Koback M, Michael AC, Dixon CE:  Controlled Cortical Impact Injury Influences Methylphenidate Induced Changes In Striatal Dopamine Neurotransmission.  J Neurochem. 2009 Aug;110(3):801-10.
  55. Wang HE, Simeone SJ, Weaver MD, Callaway CW:  Interruptions in cardiopulmonary resuscitation from paramedic endotracheal intubation.  Ann Emerg Med. 2009 Nov;54(5):645-652.e1.
2008
  1. Ahmad M, Rose ME, Vagni V, Griffith RP, Dixon CE, Kochanek PM, Hickey RW, Graham SH:  Genetic disruption of cyclooxygenase-2 does not improve histological or behavioral outcome after traumatic brain injury in mice.  J Neurosci Res. 2008 Dec;86(16):3605-12.
  2. Au AK, Ray PE, McBryde KD, Newman KD, Weinstein SL, Bell MJ:  Incidence of postoperative hyponatremia and complications in critically-ill children treated with hypotonic and normotonic solutions.  J Pediatr 152:33-38, 2008.
  3. Bayır H, Kagan VE:  Bench-to-bedside review: Mitochondrial injury, oxidative stress and apoptosis – there is nothing more practical than a good theory. Crit Care 12:206, 2008.
  4. Bell MJ, Kochanek PM: Traumatic brain injury in children: recent advances in management. Indian J Pediatr. 2008 Nov;75(11):1159-65.
  5. Betz AE, Callaway CW, Hostler D, Rittenberger JC: Work of CPR during two different compression to ventilation ratios with real-time feedback. Resuscitation. 2008 Nov;79(2):278-82.
  6. Callaway CW:  Why does the sensitivity of computed tomographic scan for detecting subarachnoid blood never improve? Ann Emerg Med 2008; 51:705-706.
  7. Callaway CW, Ramos R, Logue ES, Betz AE, Wheeler M, Repine MJ: Brain-derived neurotrophic factor does not improve recovery after cardiac arrest in rats. Neurosci Lett. 2008 Nov 7;445(1):103-7.
  8. Cheng JP, Hoffman AN, Zafonte RD, Kline AE: A delayed and chronic treatment regimen with the 5-HT(1A) receptor agonist 8-OH-DPAT after cortical impact injury facilitates motor recovery and acquisition of spatial learning.  Behav Brain Res 194:79-85, 2008.
  9. Clark RS, Bayır H, Chu CT, Alber SM, Kochanek PM, Watkins SC:  Autophagy is increased in mice after traumatic brain injury and is detectable in human brain after trauma and critical illness. Autophagy 4:88-90, 2008.
  10. Crane SA, Callaway CW, Milbrandt EB, Huang DT:  Rethinking bystander CPR for out-of-hospital cardiac arrest. Crit Care 12:302, 2008.
  11. Drabek T, Han F, Garman RH, Stezoski J, Tisherman SA, Stezoski SW, Morhard RC, Kochanek PM:  Assessment of the delta opioid agonist DADLE in a rat model of lethal hemorrhage treated by emergency preservation and resuscitation.  Resuscitation 77:220-228, 2008.
  12. Drabek T, Kochanek PM:  In quest of the optimal cooling device: isn’t faster “too fast”? Crit Care Med 36:1018-1020, 2008.
  13. Fink EL, Lai Y, Zhang X, Janesko-Feldman K, Adelson PD, Szabó C, Berger RP, Sarnaik AA, Kochanek PM, Clark RS:  Quantification of poly(ADP-ribose)-modified proteins in cerebrospinal fluid from infants and children after traumatic brain injury. J Cereb Blood Flow Metab 28:1523-1529, 2008.
  14. Foley LM, Hitchens TK, Melick JA, Bayır H, Ho C, Kochanek PM:  Effect of inducible nitric oxide synthase on cerebral blood flow after experimental traumatic brain injury in mice.  J Neurotrauma 25:299-310, 2008.
  15. Han F, Drabek T, Stezoski J, Janesko-Feldman K, Stezoski SW, Clark RS, Bayır H, Tisherman SA, Kochanek PM:  Protein nitration and poly-ADP-ribosylation in brain after rapid exsanguination cardiac arrest in a rat model of emergency preservation and resuscitation.  Resuscitation. 2008 Nov;79(2):301-10.
  16. Hartman M, Watson RS, Linde-Zwirble W, Clermont G, Weissfeld L, Lave JR, Kochanek P, Angus D:  Pediatric traumatic brain injury is inconsistently regionalized in the US.  Pediatrics 122(1):e172-80, 2008.
  17. Hoffman AN, Malena RR, Westergom BP, Luthra P, Cheng JP, Aslam HA, Zafonte RD, Kline AE: Environmental enrichment-mediated functional improvement after experimental traumatic brain injury is contingent on task-specific neurobehavioral experience.  Neurosci Lett 431:226-230, 2008.
  18. Hoffman AN, Cheng JP, Zafonte RD, Kline AE:  Administration of haloperidol and risperidone after neurobehavioral testing hinders the recovery of traumatic brain injury-induced deficits. Life Sci 83:602-607, 2008.
  19. Hsu AA, Fenton K, Weinstein S, Carpenter J, Dalton H, Bell MJ:  Neurological injury markers in children with septic shock. Pediatr Crit Care Med 9:245-251, 2008.
  20. Kline AE, Hoffman AN, Cheng JP, Zafonte RD, Massucci JL: Chronic administration of antipsychotics impede behavioral recovery after experimental traumatic brain injury. Neurosci Lett. 2008 Dec 31;448(3):263-7.
  21. Kochanek PM, Berger RP, Bayr H, Wagner AK, Jenkins LW, Clark RS:  Biomarkers of primary and evolving damage in traumatic and ischemic brain injury: diagnosis, prognosis, probing mechanisms, and therapeutic decision making.  Curr Opin Crit Care 14:135-141, 2008.
  22. Kochanek PM, Bell MJ, Adelson PD:  Hypothermia therapy after traumatic brain injury in children.  N Engl J Med 359:1179; author reply 1180, 2008.
  23. Lai Y, Hickey RW, Chen Y, Bayır H, Sullivan ML, Chu CT, Kochanek PM, Dixon CE, Jenkins LW, Graham SH, Watkins SC, Clark RS:  Autophagy is increased after traumatic brain injury in mice and is partially inhibited by the antioxidant gamma-glutamylcysteinyl ethyl ester.  J Cereb Blood Flow Metab 28:540-550, 2008.
  24. Lai Y, Chen Y, Watkins SC, Nathaniel PD, Guo F, Kochanek PM, Jenkins LW, Szabo C, Clark RS:  Identification of poly-ADP-ribosylated mitochondrial proteins after traumatic brain injury.  J Neurochem 104:1700-1711, 2008.
  25. Majerske CW, Mihalik JP, Ren D, Collins MW, Reddy CC, Lovell MR, Wagner AK:  Concussion in sports: postconcussive activity levels, symptoms, and neurocognitive performance. J Athl Train  43:265-274, 2008.
  26. Manole MD, Hickey RW, Clark RS, Kochanek PM:  Current and future therapies of pediatric cardiopulmonary arrest.  Indian J Pediatr  75:609-614, 2008.
  27. Moore TM, Callaway CW, Hostler D:  Core temperature cooling in healthy volunteers after rapid intravenous infusion of cold and room temperature saline solution.  Ann Emerg Med 51:153-159, 2008.
  28. Neumar RW, Nolan JP, Adrie C, Aibiki M, Berg RA, Böttiger BW, Callaway C, Clark RS, Geocadin RG, Jauch EC, Kern KB, Laurent I, Longstreth WT Jr, Merchant RM, Morley P, Morrison LJ, Nadkarni V, Peberdy MA, Rivers EP, Rodriguez-Nunez A, Sellke FW, Spaulding C, Sunde K, Vanden Hoek T: Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. A consensus statement from the International Liaison Committee on Resuscitation (American Heart Association, Australian and New Zealand Council on Resuscitation, European Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Asia, and the Resuscitation Council of Southern Africa); the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; and the Stroke Council. Circulation. 2008 Dec 2;118(23):2452-83.
  29. Nichol G, Thomas E, Callaway CW, Hedges J, Powell JL, Aufderheide TP, Rea T, Lowe R, Brown T, Dreyer J, Davis D, Idris A, Stiell I; Resuscitation Outcomes Consortium Investigators: Regional variation in out-of-hospital cardiac arrest incidence and outcome. JAMA. 2008 Sep 24;300(12):1423-31. Erratum in: JAMA. 2008 Oct 15;300(15):1763.
  30. Nolan JP, Neumar RW, Adrie C, Aibiki M, Berg RA, Böttiger BW, Callaway C, Clark RS, Geocadin RG, Jauch EC, Kern KB, Laurent I, Longstreth WT, Merchant RM, Morley P, Morrison LJ, Nadkarni V, Peberdy MA, Rivers EP, Rodriguez-Nunez A, Sellke FW, Spaulding C, Sunde K, Hoek TV: Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. A Scientific Statement from the International Liaison Committee on Resuscitation; the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; the Council on Stroke. Resuscitation. 2008 Dec;79(3):350-79.
  31. Raina KD, Callaway C, Rittenberger JC, Holm MB: Neurological and functional status following cardiac arrest: method and tool utility. Resuscitation. 2008 Nov;79(2):249-56.
  32. Rittenberger JC, Hostler DP, Tobin T, Gaines J, Callaway CW:  Predictors of ROSC in witnessed aeromedical cardiac arrests.  Resuscitation 76:43-64, 2008
  33. Rittenberger JC, Guyette FX, Tisherman SA, DeVita MA, Alvarez RJ, Callaway CW: Outcomes of a hospital-wide plan to improve care of comatose survivors of cardiac arrest. Resuscitation. 2008 Nov;79(2):198-204.
  34. Sarnaik AA, Conley YP, Clark RS: Susceptibility to meningococcal infection–nature versus nurture? Pediatr Crit Care Med. 2008 Sep;9(5):540-2.
  35. Sharangpani A, Takanohashi A, Bell MJ:  Caspase activation in fetal rat brain following experimental intrauterine inflammation. Brain Res 1200C:138-145, 2008.
  36. Tehranian R, Rose ME, Vagni V, Pickrell AM, Griffith RP, Liu H, Clark RSB, Dixon CE, Kochanek PM, Graham SH:  Disruption of Bax Protein Prevents Neuronal Cell Death but Produces Cognitive Impairment in Mice following Traumatic Brain Injury. J Neurotrauma 25:755-767, 2008.
  37. Tisherman SA, Bokhari F, Collier B, Cumming J, Ebert J, Holevar M, Kurek S, Leon S, Rhee P:  Clinical practice guideline: penetrating zone II neck trauma. J Trauma 64:1392-405, 2008.
  38. Tyurin VA, Tyurina YY, Feng W, Mnuskin A, Jiang J, Tang M, Zhang X, Zhao Q, Kochanek PM, Clark RS, Bayir H, Kagan VE: Mass-spectrometric characterization of phospholipids and their primary peroxidation products in rat cortical neurons during staurosporine-induced apoptosis. J Neurochem. 2008 Dec;107(6):1614-33.
  39. Tyurin VA, Tyurina YY, Kochanek PM, Hamilton R, DeKosky ST, Greenberger JS, Bayır H, Kagan VE:  Oxidative lipidomics of programmed cell death.  Methods Enzymol 442:375-393, 2008.
  40. Wu X, Drabek T, Tisherman SA, Henchir J, Stezoski SW, Culver S, Stezoski J, Jackson EK, Garman R, Kochanek PM:  Emergency preservation and resuscitation with profound hypothermia, oxygen, and glucose allows reliable neurological recovery after 3 h of cardiac arrest from rapid exsanguination in dogs. J Cereb Blood Flow Metab 28:302-311, 2008.
2007
  1. Bayır H, Kagan VE, Clark RSB, Janesko-Feldman K, Zhang X, Vagni V, Billiar TR, Kochanek PM:  Neuronal NOS-mediated nitration and inactivation of manganese superoxide dismutase in brain after experimental and human brain injury.  J Neurochem 101:168-181, 2007.
  2. Bayır H, Tyurin VA, Tyurina YY, Viner R, Ritov V, Amoscato AA, Zhao Q, Zhang XJ, Janesko-Feldman KL, Alexander H, Basova LV, Clark RS, Kochanek PM, Kagan VE: Selective early cardiolipin peroxidation after traumatic brain injury: an oxidative lipidomics analysis.  Ann Neurol 62:154-169, 2007.
  3. Beers SR, Berger RP, Adelson PD: Outcomes; Neurocognitive Outcome and Serum Biomarkers in Inflicted versus Non-Inflicted Traumatic Brain Injury in Young Children. J Neurotrauma 24:97-105, 2007.
  4. Berger RP, Beers SR, Richichi R, Wiesman D, Adelson PD:  Serum biomarker concentrations and outcome after pediatric traumatic brain injury.  J Neurotrauma 24:1793-1801, 2007.
  5. Buttram SD, Wisniewski SR, Jackson EK, Adelson PD, Feldman K, Bayir H, Berger RP, Clark RS, Kochanek PM:  Multiplex assessment of cytokine and chemokine levels in cerebrospinal fluid following severe pediatric traumatic brain injury: Effects of moderate hypothermia. J Neurotrauma 24:1707-1718, 2007.
  6. Cao G, Xing J, Xiao X, Liou AK, Gao Y, Yin XM, Clark RS, Graham SH, Chen J:  Critical role of calpain I in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury.  Critical role of calpain I in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury.  J Neurosci 27:9278-9293, 2007.
  7. Cheng JP, Aslam HA, Hoffman AN, Zafonte RD, Kline AE:  The neurobehavioral benefit conferred by a single systemic administration of 8-OH-DPAT after brain trauma is confined to a narrow therapeutic window.  Neurosci Lett 416:165-8, 2007.
  8. Clark RSB, Nathaniel PD, Zhang X, Dixon CE, Alber S, Watkins SC, Melick J, Kochanek PM, Graham SH: boc-Aspartyle(OMe)-Fluoromethylketone attenuates mitochondrial release of cytochrome c and delays brain tissue loss after traumatic brain injury in rats. J Cereb Blood Flow Metab 27:316-326, 2007.
  9. Clark RS, Vagni VA, Nathaniel PD, Jenkins LW, Dixon CE, Szabo C:  Local administration of the poly(ADP-ribose) polymerase inhibitor INO-1001 prevents NAD+ depletion and improves water maze performance after traumatic brain injury in mice.  J Neurotrauma 24:1399-1405, 2007.
  10. DeKosky ST, Abrahamson EE, Ciallella JR, Paljug WR, Wisniewski SR, Clark RS, Ikonomovic MD:  Association of increased cortical soluble abeta42 levels with diffuse plaques after severe brain injury in humans. Arch Neurol Apr;64:541-544, 2007.
  11. Dennis AM, Kochanek PM: Pathobiology of Blast Injury. Yearbook of Intensive Care and Emergency Medicine, J. L. Vincent (ed). Springer-Verlag, Berlin. pp. 1011-1022, 2007.. Springer-Verlag, Berlin. pp. 1011-1022, 2007.
  12. Dixon CE, Kline AE. Neurotransmitters and electrophysiology in brain injury. In: Nervous System Dysfunction and Injury (Banik NL, Vol. Editor). Handbook of Neurochemistry and Molecular Neurobiology, Volume 24 Springer. (In press, 2007).
  13. Drabek T, Fisk JA, Dixon CE, Garman RH, Stezoski J, Wisniewski SR, Wu X, Tisherman SA, Kochanek PM:  Prolonged deep hypothermic circulatory arrest in rats can be achieved without cognitive deficit.  Life Sci 81:543-552, 2007.
  14. Drabek T, Stezoski J, Garman RH, Wu X, Tisherman SA, Stezoski SW, Fisk JA, Jenkins L, Kochanek PM: Emergency preservation and delayed resuscitation allows normal recovery after exsanguination cardiac arrest in rats: a feasibility trial. Crit Care Med 35:532-537, 2007. Accompanying editorial by Alam HB. To cool or not to cool, that is the question. Crit Care Med 35:660-662, 2007.
  15. Drabek T, Stezoski J, Garman RH, Han F, Henchir J, Tisherman SA, Stezoski SW, Kochanek PM:  Exsanguination cardiac arrest in rats treated by 60 min, but not 75 min, emergency preservation and delayed resuscitation is associated with intact outcome. Resuscitation 75:114-123, 2007.
  16. Fink EL, Callaway CW, Tisherman SA, Kochanek PM:  Winning the cold war: Inroads into implementation of mild hypothermia after cardiac arrest in adults from the European Resuscitation Council Hypothermia After Cardiac Arrest Registry Study Group. Crit Care Med 35:1199-1202, 2007.
  17. Fink EL, Callaway CW, Tisherman SA, Kochanek PM:  Hypothermia in traumatic brain injury.  Crit Care Med 35:1999-2000, 2007.
  18. Gao W, Chadha MS, Berger RP, Omenn G, Allen D, Pisano M, Adelson PD, Clark RSB, Jenkins LW, Kochanek PM: Biomarkers and diagnosis: A gel-based proteomic comparison of human cerebrospinal fluid between inflicted and non-inflicted pediatric traumatic brain injury. J Neurotrauma: 24:43-53, 2007.
  19. Ho Y, Logue E, Callaway CW, Defranco DB: Different mechanisms account for extracellular-signal regulated kinase activation in distinct brain regions following global ischemia and reperfusion. Neuroscience 145:248-55, 2007.
  20. Hostler D, Callaway CW, Newman DH, D’Cruz B: Thrombin-Antithrombin Appearance in Out-of-Hospital Cardiac Arrest. Prehosp Emerg Care 11:9-13, 2007.
  21. Hostler D, Rittenberger JC, Roth R, Callaway CW:  Increased chest compression to ventilation ratio improves delivery of CPR. Resuscitation 74:446-452, 2007.
  22. Janata A, Bayegan K, Weihs W, Schratter A, Holzer M, Frossard M, Sipos W, Springler G, Schmidt P, Sterz F, Losert UM, Laggner AN, Kochanek PM, Behringer W:  Emergency preservation and resuscitation improve survival after 15 minutes of normovolemic cardiac arrest in pigs.  Crit Care Med 35:2785-2791, 2007.
  23. Kagan VE, Jiang J, Bayır H, Stoyanovsky DA:  Targeting nitroxides to mitochondria: location, location, location, and …concentration: highlight commentary on “Mitochondria superoxide dismutase mimetic inhibits peroxide-induced oxidative damage and apoptosis: role of mitochondrial superoxide”.  Free Radic Biol Med 43:348-350, 2007.
  24. Kapralov AA, Kurnikov IV, Vlasova II, Belikova NA, Tyurin VA, Basova LV, Zhao Q, Tyurina YY, Jiang J, Bayır H, Vladimirov YA, Kagan VE:  The Hierarchy of structural transitions induced in cytochrome c by anionic phospholipids determines its peroxidase activation and selective peroxidation during apoptosis in cells.  Biochemistry 46:14232-14244, 2007.
  25. Kentner R, Safar P, Behringer W, Wu X, Henchir J, Ma L, Hsia CJ, Tisherman SA:  Small volume resuscitation with tempol is detrimental during uncontrolled hemorrhagic shock in rats. Resuscitation 72:295-305, 2007.
  26. Kline AE, Wagner AK, Westergom BP, Malena RR, Zafonte RD, Olsen AS, Sozda CN, Luthra P, Panda M, Cheng JP, Aslam HA:  Acute treatment with the 5-HT(1A) receptor agonist 8-OH-DPAT and chronic environmental enrichment confer neurobehavioral benefit after experimental brain trauma. Behav Brain Res 177:186-194, 2007.
  27. Kline AE, Massucci JL, Zafonte RD, Dixon CE, Defeo JR, Rogers EH:  Differential effects of single versus multiple administrations of haloperidol and risperidone on functional outcome after experimental brain trauma.  Crit Care Med 35:919-924, 2007.
  28. Kochanek PM, Berger RP, Margulies SS, Jenkins LW: Inflicted childhood neurotrauma: new insight into the detection, pathobiology, prevention, and treatment of our youngest patients with traumatic brain injury. J Neurotrauma 24:1-4, 2007.
  29. Lo BM, Quinn SM, Hostler D, Callaway CW:  Rescue shock outcomes during out-of-hospital cardiac arrest.  Resuscitation 75:469-475, 2007.
  30. Logue ES, McMichael MJ, Callaway CW:  Comparison of the effects of hypothermia at 33˚C or 35˚C after cardiac arrest in rats.  Acad Emerg Med 14:293-300, 2007.
  31. Rittenberger JC, Menegazzi JJ, Callaway CW: Association of delay to first intervention with return of spontaneous circulation in a swine model of cardiac arrest.  Resuscitation 73:154-160, 2007.
  32. Shore PM, Berger RP, Varma S, Janesko KL, Wisniewski SR, Clark RS, Adelson PD, Thomas NJ, Lai YC, Bayir H, Kochanek PM: Biomarkers and Diagnosis; Cerebrospinal Fluid Biomarkers versus Glasgow Coma Scale and Glasgow Outcome Scale in Pediatric Traumatic Brain Injury: The Role of Young Age and Inflicted Injury. J Neurotrauma 24:75-86, 2007.
  33. Stippler M, Fischer MR, Puccio AM, Wisniewski SR, Carson-Walter EB, Dixon CE, Walter KA:  Serum and cerebrospinal fluid magnesium in severe traumatic brain injury outcome.  J Neurotrauma 24:1347-1354, 2007.
  34. Tortorici MA, Kochanek PM, Poloyac SM:  Effects of hypothermia on drug disposition, metabolism, and response: A focus of hypothermia-mediated alterations on the cytochrome P450 enzyme system.  Crit Care Med 35:2196-2204, 2007. Review.
  35. Tyurina YY, Basova LV, Konduru NV, Tyurin VA, Potapovich AI, Cai P, Bayır H, Stoyanovsky D, Pitt BR, Shvedova AA, Fadeel B, Kagan VE: Nitrosative stress inhibits the aminophospholipid translocase resulting in phosphatidylserine externalization and macrophage engulfment: Implications for the resolution of inflammation.  J Biol Chem 282:8498-8509, 2007.
  36. Tyurin VA, Tyurina YY, Osipov AN, Belikova NA, Basova LV, Kapralov AA, Bayır H, Kagan VE. Interactions of cardiolipin and lyso-cardiolipins with cytochrome c and tBid: conflict or assistance in apoptosis. Cell Death Differ 14:872-875, 2007.
  37. Venneti S, Wagner AK, Wang G, Slagel SL, Chen X, Lopresti BJ, Mathis CA, Wiley CA:  The high affinity peripheral benzodiazepine receptor ligand DAA1106 binds specifically to microglia in a rat model of traumatic brain injury: implications for PET imaging.  Exp Neurol 207:118-127, 2007.
  38. Wagner AK, McElligott J, Chan L, Wagner EP 2nd, Segal NA, Gerber LH:   How gender impacts career development and leadership in rehabilitation medicine: a report from the AAPM&R research committee.  Arch Phys Med Rehabil 2007 May; 88(5):560-568.
  39. Wagner AK, Kline AE, Ren D, Willard LA, Wenger MK, Zafonte RD, Dixon CE:  Gender associations with chronic methylphenidate treatment and behavioral performance following experimental traumatic brain injury.  Behav Brain Res 181(2):200-209.
  40. Wagner AK, Ren D, Conley YP, Ma X, Kerr ME, Zafonte RD, Puccio AM, Marion DW, Dixon CE:  Sex and genetic associations with cerebrospinal fluid dopamine and metabolite production after severe traumatic brain injury.  J Neurosurg 106(4):538-547, 2007.
  41. Wagner AK, Postal BA, Darrah SD, Chen X, Khan AS: Deficits in novelty exploration after controlled cortical impact.  J Neurotrauma 24:1308-1320, 2007.
  42. Yan HQ, Ma X, Chen X, Li Y, Shao L, Dixon CE: Delayed increase of tyrosine hydroxylase expression in rat nigrostriatal system after traumatic brain injury. Brain Res 1134:171-179, 2007.