Mioara D. Manole, MD, FAAP

Mioara D. Manole, MD, FAAP

Congratulations to Dr. Mioara Manole for being awarded a prestigious Transformational Project Award from the American Heart Association.

Using an innovative optogenetic approach, her team will determine if targeted relaxation of vascular smooth muscle cells and pericytes in the cerebral cortex improves cortical perfusion, oxygenation, and neuronal function after cardiac arrest in mice. This work builds on her studies targeting the “no reflow” phenomenon in the brain that she previously characterized after experimental cardiac arrest.

Alberto L. Vazquez, PhD

Alberto L. Vazquez, PhD

These studies will be carried out in collaboration with Dr. Alberto Vazquez from the Departments of Radiology and Bioengineering.