Dr. Corina Bondi, Associate Director of Executive Function and Neuropharmacology and Safar Center colleague, Dr. Mioara Manole, Associate Director of Pediatric Emergency Medicine, were awarded a Childrens’ Neuroscience Institute Interdisciplinary Neuroscience Award titled “Neurobehavioral and Physiological Effects of Traumatic Brain Injury (TBI) in Spontaneously Hypertensive Rats.”
Drs. Bondi and Manole aim to remedy the paucity of studies examining comorbidities during the TBI recovery phase, by exploring how adult-onset high blood pressure, a common underlying condition for approximately 50% of adults, may affect pediatric TBI-induced long-term motor, complex cognitive, and anxiety-like impairments. The findings from these proposed preclinical studies will advance knowledge of neurobehavioral and histopathological alterations in adult survivors of childhood brain trauma living with comorbid hypertension. The investigations also seek to identify mechanisms through which therapeutic and rehabilitative approaches may be targeted to improve outcomes.
Congratulations to the Safar Center’s Romanian-born team!