2007
Neurointensive Care and Resuscitation Research Journal Club |
Date |
Presenters |
Title |
12/21/2007 |
Robert Hickey, MD |
In vivo and in vitro Characterization of a Novel Neuroprotective Strategy for Stroke: Ischemic Postconditioning |
| |
Bob Garman, DVM |
Translating Developmental Time Across Mammalian Species. |
| |
Mioara Manole, MD |
Hyperoxide Reperfusion after Global Ischemia Decreases Hippocampal Energy Metabolism. |
12/7/2007 |
Empey |
Change in Pharmacokinetics of Model Compounds with Different Elimination Processes in Rats during Hypothermia. |
| |
Dave Shellington, MD |
Essential Protective Roles of Reactive Astrocytes in Traumatic Brain Injury. |
| |
Hoffman |
Nicotinamide treatment Reduces Behavioral Impairments and Provides Cortical Protection after Fluid Percussion Injury in the Rat |
11/30/2007 |
James Bales, MD |
Neurotrophin-Mediated Neuroprotection of Hippocampal Neurons Following Traumatic Brain Injury is Not Associated with Acute Recovery of Hippocampal Function. |
| |
Dave Shellington, MD; Empey |
Microglia Induce Neurotoxicity via Intraneural ZN2+ Release and a K+ Current Surge. |
11/9/2007 |
Patrick Kochanek, MD |
A trial of therapeutic hypothermia via endovascular approach in awake patients with acute ischemic stroke: Methodology. |
|
Mioara Manole, MD |
A nitric oxide donor reduces brain injury and enhances recovery of cerebral blood flow after hypoxia-ischemia in the newborn rat. |
10/19/2007 |
Anthony Kline, PhD |
Chronic Cognitive Deficits and Long-Term Histopathological Alterations following Contusive Brain Injury in the Immature Rat. |
|
Ying Mu, MD, PhD |
Successful cardiopulmonary resuscitation after cardiac arrest as a "sepsis-like" syndrome. |
10/12/2007 |
Jennifer Exo, MD |
Association between cerebrospinal fluid levels of asymmetric dimethyl-L-arginine, an endogenous inhibitor of endothelial nitric oxide synthase, and cerebral vasospasm in a primate model of subarachnoid hemorrhage. |
|
Ajit Sarnaik, MD |
In situ localization of P-glycoprotein (ABCB1) in human and rat brain. |
10/05/2007 |
James Bales, MD |
Epigenetic modulation of seizure-induced neurogenesis and cognitive decline. |
|
Bob Clark, MD |
Ketamine-induced neuronal cell death in the perinatal rhesus monkey. |
9/28/2007 |
Hülya Bayır, MD |
Selective dysfunction of hippocampal CA1 astrocytes contributes to delayed neuronal damage after transient forebrain ischemia. |
|
Craig Smith, MD |
Transvascular delivery of small interfering RNA to the central nervous system. |
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Martina Stippler, MD |
Biomarkers and diagnosis; protein biomarkers in serum of pediatric patients with severe traumatic brain injury identified by ICAT-LC-MS/MS. |
9/21/2007 |
Karen Walson, MD |
Attenuation of oxidative injury after induction of experimental intracerebral hemorrhage in heme oxygenase-2 knockout mice. |
|
Bob Garman, DVM |
Dual role of intrauterine immune challenge on neonatal and adult brain vulnerability to hypoxia-ischemia. |
9/14/2007 |
Jocelyn Zhou, PhD |
Repeated treatment with cannabidiol but not Delta9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance. |
|
Hülya Bayır, MD |
Saline or albumin for fluid resuscitation in patients with traumatic brain injury. |
8/31/2007 |
Martina Stippler, MD |
TRPMs and neuronal cell death. |
|
Dave Shellington, MD |
Metalloproteinases are enriched in microglia compared with leukocytes and they regulate cytokine levels in activated microglia. |
8/24/2007 |
Dave Shellington, M.D. |
Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration. |
|
Minke Tang, M.D. |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. |
8/17/2007 |
Bob Garman, D.V.M. |
Perisomatic thalamic axotomy after diffuse traumatic brain injury is associated with atrophy rather than cell death. |
|
Mike Bell, M.D. |
Selective vulnerability of preterm white matter to oxidative damage defined by F2-isoprostanes. |
8/10/2007 |
Craig Smith, M.D. |
Use of opioids in asphyxiated term neonates: effects on neuroimaging and clinical outcome. |
|
Mioara Manole, M.D. |
Polynitroxyl albumin reduces infarct size in transient focal cerebral ischemia in the rat: potential mechanisms studied by magnetic resonance imaging. |
|
Ericka Fink, M.D. |
Erythropoietin protects from post-traumatic edema in the rat brain. |
8/3/2007 |
Megan Miller |
Increased risk of late posttraumatic seizures associated with inheritance of APOE epsilon4 allele. |
|
Bob Clark, M.D. |
Increased pentose phosphate pathway flux after clinical traumatic brain injury: a [1,2-(13)C(2)]glucose labeling study in humans. |
|
Dave Shellington, M.D. |
The high affinity peripheral benzodiazepine receptor ligand DAA1106 binds specifically to microglia in a rat model of traumatic brain injury: Implications for PET imaging. |
7/27/2007 |
Martina Stippler, M.D. |
Tryptophan metabolism and oxidative stress in patients with chronic brain injury. |
|
Sheila Alexander, Ph.D. |
Long-lasting regeneration after ischemia in the cerebral cortex. |
|
Karen Walson, M.D. |
Haptoglobin and the development of cerebral artery vasospasm after subarachnoid hemorrhage. |
7/20/2007 |
Anthony Kline, Ph.D. |
The Novel Apolipoprotein E-Based Peptide COG1410 Improves Sensorimotor Performance and Reduces Injury Magnitude following Cortical Contusion Injury. |
|
Ajit Sarnaik, M.D. |
Neuroprotective effect of erythropoietin, and role of metallothionein-1 and -2, in permanent focal cerebral ischemia. |
7/6/2007 |
Bob Garman, DVM |
Bilateral changes after neonatal ischemia in the P7 rat brain. |
|
Martina Stippler, M.D. |
Acute metabolic brain changes following traumatic brain injury and their relevance to clinical severity and outcome. |
|
Sheila Alexander, Ph.D. |
Apolipoprotein E-containing lipoproteins protect neurons from apoptosis via a signaling pathway involving low-density lipoprotein receptor-related protein-1 |
6/29/2007 |
Brett Postal |
Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury |
| |
Jocelyn Zhou, Ph.D. |
In Vivo Activation of Human Pregnane X Receptor Tightens the Blood-Brain Barrier to Methadone through P-Glycoprotein Up-Regulation |
| |
Sam Poloyac, Ph.D. |
Role of drug efflux carriers in the healthy and diseased brain. |
6/7/2007 |
Craig Smith, M.D. |
Inhibition of caspase-mediated apoptosis by peroxynitrite in traumatic brain injury. |
| |
Patrick M. Kochanek, M.D. |
Downregulation of hippocampal adenosine kinase after focal ischemia as potential endogenous neuroprotective mechanism. |
5/11/2007 |
Minke Tang, M.D. |
Evidence of a protective effect of phosphatidylserine-containing liposomes on lipopolysaccharide-induced impairment of long-term potentiation in the rat hippocampus. |
|
Martina Stippler, M.D. |
Magnesium sulfate for neuroprotection after traumatic brain injury: a randomised controlled trial. |
4/27/2007 |
Rachel Berger, M.D. |
Diffusion Tensor Imaging in the Corpus Callosum in Children after Moderate to Severe Traumatic Brain Injury. |
|
Amy Wagner, M.D. |
Detection of Traumatic Axonal Injury with Diffusion Tensor Imaging in a Mouse Model of Traumatic Brain Injury. |
|
Joelle Scanlon, M.D. |
Principles of Diffusion Tensor Imaging and its Applications to Basic Neuroscience Research. |
4/20/2007 |
Craig Smith, M.D. |
Minocycline Attenuates Hypoxia-Ischemia-Induced Neurological Dysfunction and Brain Injury in the Juvenile Rat. |
|
Ajit Sarnaik, M.D. |
Naloxone and Epinephrine are Equally Effective for Cardiopulmonary Resuscitation in a Rat Asphyxia Model. |
|
Patrick M. Kochanek, M.D. |
Opposed Effects of Hypertonic Saline on Contusions and Noncontused Brain Tissue in Patients with Severe Traumatic Brain Injury. |
4/11/2007 |
Ericka Fink, M.D. |
Clinical Application of Mild Therapeutic Hypothermia after Cardiac Arrest. |
|
Bob Clark, M.D. |
Rapamycin is a Neuroprotective Treatment for Traumatic Brain Injury. |
|
Larry Jenkins, Ph.D. |
Regulation of Neuronal PKA Signaling through AKAP Targeting Dynamics. |
4/6/2007 |
Tomas Drabek, M.D. |
Cardiopulmonary Resuscitation Bystanders with Chest Compression only (SOS-KANTO): An Observational Study. |
|
Mioara Manole, M.D. |
Acute Cerebral Blood Flow Variations after Human Cardiac Arrest Assessed by Stable Xenon Enhanced Computed Tomography. |
|
Ajit Sarnaik, M.D. |
Effects of Hypertonic Arginine on Cerebral Blood Flow and Intracranial Pressure after Traumatic Brain Injury Combined with Hemorrhagic Hypotension. |
3/7/2007 |
Sheila Alexander, Ph.D. |
Temporal Changes in Cerebral Tissue Oxygenation with Cerebrovascular Pressure Reactivity in Severe Traumatic Brain Injury. |
|
Tomas Drabek, M.D. |
A Comparison of Electrically Induced Cardiac Arrest with Cardiac Produced by Coronary Occlusion. |
|
Hülya Bayır, M.D. |
Apoptosis-Inducing Factor is a Major Contributor to Neuronal Loss Induced by Neonatal Cerebral Hypoxia-Ischemia. |
2/23/2007 |
David Shellington, M.D. |
White Matter Plasticity and Enhanced Remyelination in the Maternal CNS. |
|
Minke Tang, M.D. |
Apoptotic PC12 Cells Exposing Phosphatidylserine Promote the Production of Anti-Inflammatory and Neuroprotective Molecules by Microglial Cells. |
|
Robert Hickey, M.D. |
Endoplasmic Reticulum Stress Inhibition Protects Against Excitotoxic Neuronal Injury in the Rat Brain. |
2/2/2007 |
Anthony Kline, Ph.D. |
Embryonic Stem Cell Transplantation after Experimental Traumatic Brain Injury Dramatically Improves Neurological Outcome, but may cause Tumors. |
|
Sheila Alexander, Ph.D. |
Hyperventilation Following Head Injury: Effect on Ischemic Burden and Cerebral Oxidative Metabolism. |
|
Tomas Drabek, M.D. |
Hydrogen Sulfide Attenuates Lipopolysaccharide-Induced Inflammation by Inhibition of p38 Mitogen-Activated Protein Kinase in Microglia. |
1/26/2007 |
Bob Garman, D.V.M. |
Dopaminergic Substantia Nigra Neurons Project Topographically Organized to the Subventricular Zone and Stimulate Precursor Cell Proliferation in Aged Primates. |
|
Larry Jenkins, Ph.D. |
The Artic Ground Squirrel Brain is Resistant to Injury from Cardiac Arrest during Euthermia. |
|
Patrick M. Kochanek, M.D. |
Intracranial Pressure Complicating Severe Traumatic Brain Injury in Children: Monitoring and Management. |
1/19/2007 |
Peiying Chuang, M.D. |
Neuroglobin-Overexpressing Transgenic Mice are Resistant to Cerebral and Myocardial Ischemia. |
|
Mioara Manole, M.D. |
Protective Effects of Combined Superoxide Dismutase and Deferoxamine on Recovery of Cerebral Blood Flow and Function After Cardiac Arrest in Dogs. |
|
Amy Wagner, M.D. |
Thalamic and Hippocampal Mechanisms in Spatial Navigation: A Dissociation between Brain Mechanisms for Learning how Versus Learning Where to Navigate. |
1/12/2007 |
Karen Walson, M.D. |
Modulation of the Oxidative Stress and Inflammatory Response by PPA-γ Agonists in the Hippocampus of Rats Exposed to Cerebral Ischemia/Reperfusion. |
|
Alia Dennis, M.D. |
Traumatic Brain Injury Attenuates the Effectiveness of Lactated Ringer’s Solution Resuscitation of Hemorrhagic Shock in Rats. |
|
Sheila Alexander, Ph.D. |
Analysis of the XRCCI Gene as a Modifier of the Cerebral Response in Ischemic Stroke. |
2008 | 2007 | 2006 | 2005 |
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