2005
Neurointensive Care and Resuscitation Research Journal Club |
Date |
Presenters |
Title |
12/23/05 |
Amanda Alkhalidi, Ph.D. |
Transient Decrease in F-Actin may be Necessary for Translocation of Proteins into Dendritic Spines. |
|
Tomas Drabek, M.D. |
Hypothermia Improves Defibrillation Success and Resuscitation Outcomes from Ventricular Fibrillation. |
|
Patrick M. Kochanek, M.D. |
Xenon and Hypothermia Combine to Provide Neuroprotection from Neonatal Asphyxia. |
12/16/05 |
Bob Hickey, M.D. |
Effectiveness of a 30-min CPR Self-Instruction Program for Lay Responders: A Controlled Randomized Study. |
|
Yi-Chen Lai, M.D. |
Neuronal Nitric Oxide Synthase Controls Enzyme Activity Pattern of Mitochondria and Lipid Metabolism. |
|
Patrick M. Kochanek, M.D. |
nNos Gene Deletion Exacerbates Pathological Left Ventricular Remodeling and Functional Deterioration after Myocardial Infarction. |
12/09/05 |
Tomas Drabek, M.D. |
Apoptotic Neuronal Death Following Deep Hypothermic Circulatory Arrest in Piglets. |
|
Anthony Kline, Ph.D. |
Administration of Riboflavin Improves Behavioral Outcome and Reduces Edema Formation and Glial Fibrillary Acidic Protein Expression after Traumatic Brain Injury. |
|
Patrick M. Kochanek, M.D. |
Relationship between the Arg72Pro Polymorphism of p53 and Outcome for Patients with Traumatic Brain Injury. |
12/02/05 |
Bob Garman, D.V.M. |
Moderate Ethanol Consumption Increases Hippocampal Cell Proliferation and Neurogenesis in the Adult Mouse. |
|
Hülya Bayır, M.D. |
Enhanced Neurofibrillary Tangle Formation, Cerebral Atrophy, and Cognitive Deficits Induced by Repetitive Mild Brain Injury in a Transgenic Tauopathy Mouse Model. |
11/04/05 |
Anthony Kline, Ph.D. |
Hypoxia-Ischemia Induced Neurological Dysfunction and Brain
Injury in the Neonatal Rat. |
|
Larry Jenkins, Ph.D. |
Hypoxia-ischemia Induces DNA Synthesis without Cell Proliferation
in Dying Neurons in Adult Rodent Brain. |
|
Bob Garman, D.V.M. |
Moderate Ethanol Consumption Increases Hippocampal Cell Proliferation
and Neurogenesis in the Adult Mouse. |
10/28/05 |
Mike Tortorici, Pharm. D. |
Hypothermia Reduces Microvascular Permeability and Reactive
Oxygen Species Expression after Hemorrhagic Shock. |
|
Xiangbai Chen, M.D. |
Endogenous Adult Neural Stem Cells: Limits and Potential to
Repair the Injured Central Nervous System. |
|
Ericka Fink, M.D. |
High-Volume Hemofiltration After Out-of-Hospital Cardiac Arrest. |
10/21/05 |
Tomas Drabek, M.D. |
Whole-Body Hypothermia for Neonates with Hypoxic-Ischemic
Encephalopathy |
|
Amy Wagner, M.D. |
Neuroprotection Afforded by Prior Citicoline Administration
in Experimental Brain Ischemia: Effects on Glutamate Transport |
|
Hülya Bayır, M.D. |
Enhanced Hippocampal Neurogenesis by Intraventricular S100B
Infusion is Associated with Improved Cognitive Recovery after
Traumatic Brain Injury |
10/14/05 |
Larry Jenkins, Ph.D. |
Post-translational Protein Modification
as the Substrate for Long-Lasting Memory
|
|
Bob Garman, D.V.M. |
G-CSF Suppresses Edema
Formation and Reduces Interleukin-1β Expression
after Cerebral Ischemia in Mice |
|
Patrick M. Kochanek, M.D. |
Inhibition of Nitric Oxide Production and Protein Tyrosine
Nitration contribute to Neuroprotection by a Novel Calmodulin
Antagonist, DY-9760e, in the Rat Microsphere Embolism |
10/07/05 |
Ericka Fink, M.D. |
Autologous Mesenchymal Stem Cell Transplantation
in Stroke Patients.
|
|
Anthony Kline, Ph.D. |
The Effects of Chronic Unpredictable Stress
on Male Rats in the Water Maze. |
|
Yi-Chen Lai, M.D. |
Cerebral Endothelial Cell
Apoptosis after Ischemia-reperfusion: Role of PARP Activation
and AIF Translocation. |
9/30/05 |
Patrick M. Kochanek, M.D. |
Neuroprotective Efficacy and Therapeutic
Time Window of Peroxynitrite Decomposition Catalysts in Focal
Cerebral Ischemia in Rats.
|
|
Larry Jenkins, Ph.D. |
Translational Control
of Hippocampal Synaptic Plasticity and Memory by the elf2α kinase
GCN2. |
|
Tomas Drabek, M.D. |
Efficacy of Intranasal Naloxone as a Needleless Alternative
for Treatment of Opioid Overdose in the Prehospital Setting. |
9/23/05 |
Hülya Bayır, M.D. |
The Hematopoietic Factor G-CSF is Neuronal Ligand that Counteracts
Programmed Cell Death and Drives Neurogenesis. |
|
Weimin Gao, Ph.D. |
Proteins Released from Degenerating Neurons are Surrogate Markers
for Acute Brain Damage. |
|
Patrick M. Kochanek, M.D. |
Neuroprotective Efficacy and Therapeutic Time Window of Peroxynitrite
Decomposition Catalysts in Focal Cerebral Ischemia in Rats. |
9/16/05 |
Bob Clark, M.D. |
Protein Synthesis Persists During Necrotic Cell Death. |
|
Patrick M. Kochanek, M.D. |
Effects of Epidural Hypothermic Saline Infusion on Locomotor
Outcome and Tissue Preservation after Moderate Thoracic Spinal
Cord Contusion in Rats. |
9/9/05 |
Anthony Kline, Ph.D. |
Reversal of Neuromotor and Cognitive Dysfunction
in an Enriched Environment Combined with Multimodel Early Onset
Stimulation after Traumatic Brain Injury in Rats. |
|
Bob Garman, D.V.M. |
Excitotoxicity in Perinatal Brain Injury. |
|
Tomas Drabek, M.D. |
Delaying Shock for Cardiopulmonary Resuscitation:
does it save lives? |
9/2/05 |
Ericka Fink, M.D. |
Neuronal Nitric Oxide Synthase and Ischemia Induced Neurogenesis. |
| |
Yi-Chen Lai, M.D. |
Physiological Thresholds for Irreversible Tissue Damage in Contusional Regions following Traumatic Brain Injury. |
8/26/05 |
Mike Tortorici, Pharm. D. |
AS601245 (1,3-Benzothiazol-2-yl (2-{[2-(3-Pyridinyl) ethyl]
amino}-4 pyrimidinyl) Acetonitrile): A c-Jun NH2-Terminal Protein
Kinase Inhibitor with Neuroprotective Properties. |
| |
Tomas Drabek, M.D. |
Induction of Profound Hypothermia Modulates the Immune/Inflammatory
Response in a Swine Model of Lethal Hemorrhage. |
| |
Tomas Drabek, M.D. |
The Rate of Induction of Hypothermic Arrest Determines the
Outcome in a Swine Model of Lethal Hemorrhage |
| |
Weimin Gao, Ph.D. |
Evaluation of Protein Depletion Methods for the Analysis of
Total-, Phospho- and Glycoproteins in Lumbar Cerebrospinal Fluid. |
8/19/05 |
Amanda Alkhalidi, Ph.D. |
Developmental Change in the Calcium Sensor for Synaptic Vesicle
Endocytosis in Central Nerve Terminals. |
|
Bob Garman, D.V.M. |
Ischemia Leads to Apoptosis—and
Necrosis-like Neuron Death in the Ischemic Rat Hippocampus. |
|
Yi-Chen Lai, M.D. |
Cerebral Fractional Oxygen Extraction is Inversely Correlated
with Oxygen Delivery in the Sick, Newborn, Pretern Infant. |
8/12/05 |
Amanda Alkhalidi, Ph.D. |
Role of the Cell Cycle in the Pathobiology of Central Nervous
System Trauma. |
|
Larry Jenkins, Ph.D. |
Pyruvate Dehydrogenase Complex: Metabolic Link to Ischemic
Brain Injury and Target of Oxidative Stress. |
|
Hülya Bayır, M.D. |
Human Neuroglobin Protein in Cerebrospinal Fluid. |
7/15/05 |
Weimin Gao, Ph.D. |
Cell Cycle Inhibition Provides Neuroprotection and Reduces Glial proliferation and Scar Formation after Traumatic Brain Injury.
|
|
Sam Poloyac, Ph.D. |
(In Press) Reversal of Delayed Vasospasm by an Inhibitor of the Synthesis of 20-HETE. |
|
Larry Jenkins, Ph.D. |
Spatial and Temporal Characteristics of Neurodegeneration after Controlled Cortical Impact in Mice: More than a Focal Brain Injury. |
7/8/05 |
Sheila Alexander |
VEGF and VEGF Receptor Expression after Experimental Brain Contusion in Rat.
|
|
Larry Jenkins, Ph.D. |
Signalling Specifically of SER/THr Protein Kinases through Docking-Site-Mediated Interactions |
|
Yi-Chen Lai, M.D. |
Mechanism of Cerebral Edema in Children with Diabetic Ketoacidosis. |
7/1/05 |
Jesse Fisk |
Characterizing Learning Deficits and Hippocampal Neuron Loss Following Transient Global Cerebral Ischemia in Rats
|
|
Ashley Kochanek |
Controversies in Synaptic Vesicle Exocytosis |
|
Anthony Kline, Ph.D. |
Dietary Supplementation with Blueberries, Spinach, or Spirulina Reduces Ischemic Brain Damage. |
6/17/05 |
Ericka Fink, MD |
Statins Induce Angiogenesis, Neurogenesis, and Synaptogenesis After Stroke.
|
|
Bob Garman, DVM |
Human Neural Stem Cell Transplantation Promotes Functional Recovery in Rats with Experimental Intracerebral Hemorrhage. |
|
Mandeep Chadha, MD |
Reappearance of Hippocampal CA1 Neurons after Ischemia is Associated with Recovery of Learning and Memory. |
6/10/05 |
Xianren Wu, MD |
Review: Investigational Anti-Inflammatory Agents for Treatment of Ischaemic Brain Injury.
|
|
Amy Wagner, MD |
Microglia Overexpressing the Macrophage Colony Stimulating Factor Receptor Are Neuroprotective in a Microglial-Hippocampal Organotypic Coculture System. |
|
Sandra Buttram, MD |
The Effect of Therapeutic Hypothermia on the Expression of Inflammatory Response Genes Following Moderate Traumatic Brain Injury in the Rat. |
6/03/05 |
Amanda Alkhalidi, PhD |
SHORT COMMUNICATION: Over-Expression
of the Human EAAT2 Glutamate Transporter within Neurons of
Mouse Organotypic Hippocampal Slice Cultures Leads to Increased
Vulnerability of CA1 Pyramidal Cells.
|
|
Ericka Fink, MD |
Nitric Oxide Synthase Inhibition during Synaptic Maturation
Decreases Synapsin I Immunoreactivity in Rat Brain. |
|
Larry Jenkins, PhD |
Finding the G Spot on Fusion Machinery. |
5/20/05 |
Bob Hickey, MD |
Δ12-Prostaglandin
J2 Inhibits the Ubiquitin Hydrolase UCH-L1 and Elicits Ubiquitin-Protein
Aggregation without Proteasome Inhibition. |
|
Hülya Bayır, MD |
Nitric Oxide Synthase
(NOS)-Interacting Protein Interacts with Neuronal NOS and
Regulates its Distribution and Activity. |
|
Patrick M. Kochanek, MD |
Interleukin-1
and the Interleukin-1 Type 1 Receptor are Essential for the
Progressive Neurodegeneration that Ensues Subsequent to a
Mild Hypoxic/Ischemic Injury. |
5/13/05 |
Bob Garman, DVM |
Inosine Induces Axonal
Rewiring and Improves Behavioral Outcome after Stroke. |
| |
Yi-Chen Lai, MD |
Sulfide Oxidation Coupled
to ATP Synthesis in Chicken Liver Mitochondria. |
| |
Yi-Chen Lai, MD |
Sulfide Consumption
by Mussel Gill Mitochondria is not Strictly Tied to Oxygen
Reduction: Measurements Using a Novel Polar graphic Sulfide
Sensor. |
5/6/05 |
Mandi Al-Khalidi, MD |
Synaptic Plasticity
in Micropatterned Neuronal Networks |
|
Tomas Drabek, MD |
Cardiopulmonary Bypass
Induces Neurologic and Neurocognitive Dysfunction in the
Rat |
|
Poloyak |
Local Saline Infusion
into Ischemic Territory Induces Regional Brain Cooling and
Neuroprotection in Rats with Transient Middle Cerebral Artery
Occlusion |
4/29/05 |
Lai |
DRP-1-mediated mitochondrial
fragmentation during EGL-1-induced cell death in c. elegans. |
|
Tortorici |
Haloperidol, but
not olanzapine, Impairs Cognitive performance after traumatic
brain injury. |
|
Fink |
Metabolic crisis without
brain ischemia is common after traumatic brain injury: A
combined microdialysis and positron emission tomography study.
|
4/22/05 |
Washington |
Cerebral autoregulation
in pediatric traumatic brain injury. |
|
Gao |
Intact-protein based high-resolution
three-dimensional quantitative analysis system for proteome
profiling of biological fluids. |
|
Bayır |
Lack of mitochondrial
nitric oxide production in the mouse brain.
|
|
Bayır |
Mitochondrial Nitric
Oxide Synthase is Constitutively Active and is Functionally
Upregulated in Hypoxia. |
4/15/05 |
Alkhalidi |
High rate shear
strain of three-dimensional neuronal cell cultures: A new
in vitro traumatic brain injury model. |
|
Wu |
Docosahexaenoic Acid Complexed
to Albumin Elicits High-Grade Ischemic Neuroprotection |
|
Lai |
DRP-1-mediated mitochondrial
fragmentation during EGL-1-induced cell death in C. elegans.
|
4/8/05 |
Kochanek |
General anesthesia
improves fetal cerebral oxygenation without evidence of subsequent
neuronal injury. |
|
Fink |
Association of multidrug
resistance in epilepsy with a polymorphism in the drug-transporter
gene ABCB1. |
|
Alkhalidi |
High rate shear
strain of three-dimensional neuronal cell cultures: A new
in vitro traumatic brain injury model.
|
4/1/05 |
Garman |
Current Concepts:
Memory dysfunction. |
|
Jenkins |
Epigenetic mechanisms
in memory formation. |
3/25/05 |
Wu |
Carbon monoxide-induced
suspended animation protects against hypoxic damage in caenorhabditise
elegans. |
|
Gao |
Gene deletion of cystatin
c aggravates brain damage following focal ischemia but mitigates
the neuronal injury after global ischemia in the mouse. |
|
Bayır |
Nitric oxide inhibits
caspase activation and apoptotic morphology but does not
rescue neuronal death.
|
3/18/05 |
Berger |
Total and ionized
plasma magnesium concentrations in children after traumatic
brain injury. |
|
Alkhalidi |
The importance
of dendritic mitochondria in the morphogenesis and plasticity
of spines and synapses. |
|
Kline |
Experience-dependent
behavioral plasticity is disturbed following traumatic brain
injury.
|
3/11/05 |
Drabek |
Recombinant activated
factor VII for acute intracerebral hemorrhage. |
|
Jenkins |
Epigenetic mechanisms
in memory formation. |
|
Wagner |
Noradrenaline and
dopamine elevations in the rat prefrontal cortex in spatial
working memory.
|
2/25/05 |
Alkhalidi |
Intravenous RNA interference
gene therapy targeting the human epidermal growth factor
receptor prolongs survival in intracranial brain cancer. |
|
Fink |
fMRI reveals large-scale
network activation in minimally conscious patients. |
|
Lai |
Ischemic nitric oxide
and poly(ADP-ribose) polymerase-1 in cerebral ischemia: Male
toxicity female protection.
|
|
Kochanek |
Cardiovascular
Risk Factors Emerge After Artificial Selection for Low Aerobic
Capacity |
2/18/05 |
Garman |
Effects of global ischemia
duration on neuronal, astroglial, oligodendrogliag, and microglial
reactions in the vulnerable hippocampal CA1 subregion in
rats. |
|
Wagner |
Effects of methylphenidate
on attention deficits after traumatic brain injury: A multidimensional,
randomized, controlled trial. |
|
Bayır |
Developmental lag in
superoxide dismutases relative to other antioxidant enzymes
in premyelinated human telencephalic white matter.
|
2/4/05 |
Washington |
The effects of caffeine
on ischemic neuronal injury as determined by magnetic resonance
imaging and histopathology. |
|
Wu |
Ischemic in normoglycemic
and hyperglycemic rats: Plasma energy substrates and hormones. |
|
Drabek |
Mesenteric injury after
cardiopulmonary bypass: Role of poly (adenosine 5’-diphosphate-ribose)
polymerase.
|
1/28/05 |
Alkhalidi |
Intravenous RNA interference
gene therapy targeting the human epidermal growth factor
receptor prolongs survival in intracranial brain cancer. |
|
Fink |
The influence of age on
apoptotic and other mechanisms of cell death after cerebral
hypoxia-ischemia. |
1/21/05 |
Garman |
Cyclooxygenase-2 (COX-2)
in inflammatory and degenerative brain diseases. |
|
Chen |
Alpha2-adrenoceptor mediated
co-release of dopamine and noradrenaline from noradrenergic
neurons in the cerebral cortex. |
1/14/04 |
Kline |
Treadmill exercise improves
short-term memory by suppressing ischemia-induced apoptosis
of neuronal cells in gerbils. |
|
Washington |
Status epilepticus
may be caused by loss of adenosine anticonvulsant mechanisms. |
|
Gao |
Infant rat model of the
shaken baby syndrome: Preliminary characterization and evidence
for the role of free radicals in cortical Hemorrhage and
progressive neuronal degeneration.
|
1/7/04 |
Lai |
NAD+ as a metabolic link
between DNA damage and cell death. |
|
Fink |
Topiramate extends the
therapeutic window for hypothermia-mediated neuroprotection
after smoke in neonatal rats. |
2008 | 2007 | 2006 | 2005 |
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