2015 Meetings





12/18/15 Li, Bondi

Traumatic brain injury results in rapid pericyte loss followed by reactive pericytosis in the cerebral cortex.

Closed head injury in an age-related alzheimer mouse model leads to an altered neuroinflammatory response and persistent cognitive impairment.

12/9/15 Hagos Suboptimal dosing parameters as possible factors in the negative Phase III clinical trials of progesterone for TBI.
12/4/15 Wallisch Cerebrovascular Pressure Reactivity in Children with Traumatic Brain Injury.
11/20/15 Horvat, Radabough

Erythropoietin in Traumatic Brain Injury (EPO-TBI): a Double-Blind Randomised Controlled Trial.

A Behavioral and Histological Comparison of Fluid Percussion Injury and Controlled Cortical Impact Injury to the Rat Sensormotor Cortex.

11/6/15 Pang Host microbiota constantly control maturation and function of microglia in the CNS.
10/30/15 Kowalski, Lamade

Dezfulian Student Poster Presentations:

New left bundle branch block (LBBB) is poorly predictive of coronary occlusion after Out-of-Hospital Cardiac Arrest (OHCA)

Increased Injury with Asphyxial versus VF Cardiac Arrest in Rat Brain.

10/23/15 Wallisch Aquaporin-4 distribution in control and stressed astrocytes in culture and in the cerebrospinal fluid of patients with traumatic brain injuries.
10/16/15 Horvat Hypothermia for Intracranial Hypertension after Traumatic Brain Injury
9/25/15 Simon Pivotal role of cerebral interleukin-17–producing gdT cells in the delayed phase of ischemic brain injury.
10/2/2015 Laporte   

Mean girls: Sex differences in the effects of mild traumatic brain injury on the social dynamics of juvenile rat play behavior.

9/23/2015 Horvat, Oh

Pediatric Traumatic Brian Injury and Attention Deficit.

Antibody Against Early Driver of Neurodegeneration cis P-tau Blocks Brain Injury and Tauopathy.

9/18/2015 Carlson, Cheng

Synaptogenesis in the Hippocampal CA1 Field Following Traumatic Brain Injury.

A Novel Preclinical Model of Moderate Primary Blast-Induced Traumatic Brain Injury

9/4/2015 Horvat, Pang

Plasma Biomarkers of Brian Injury as Diagnostic Tools and Outcome Predictors after Extracorporeal Membrane Oxygenation

The Effect of Body Posture on Brain Glymphatic Transport.

8/28/2015 Osier Melatonin ameliorates brain injury induced by systemic lipopolysaccharide in neonatal rats
8/14/2015 Laporte Pre and post-injury environmental enrichment effects functional recovery following medial frontal cortical contusions injury in rats.
8/7/2015 Kline Glucose Administration after traumatic brain injury exerts some benefits and no adverse effects on behavioral and histological outcomes.
7/31/2015 Hagos

Transporter-mediated L-glutamate elimination from cerebrospinal fluid: possible involvement of excitatory amino acid transporters expressed in ependymal cells and choroid plexus epithelial cells.

7/24/2015 Kenny Cellular Protection using Flt3 and PI3Ka Inhibitors Demonstrates Multiple Mechanisms of Oxidative Glutamate Toxicity.
7/17/2015 Dezfulian, Jacobs

Asphyxia-activated Corticocardiac Signaling Accelerates onset of Cardiac Arrest

Dietary Therapy Mitigates Persistent Wake Deficits Caused by
Mild Traumatic Brain Injury

7/10/2015 Pugh, Fidous Recovery of Cerebral Blood Flow Following Sport-Related Concussion
 6/26/2015 Hagos Role of the blood-cerebrospinal fluid barrier transporter as a cerebral clearance system for prostaglandin E2 produced in the brain.
6/19/2015  Pang Correlated gene expression supports synchronous activity in brain networks.
6/12/2015 Kochanek

Special Topic Journal Club: "Ethics in Research: Predatory Journals and Misrepresentation of Data"

The Dark Side of Publishing

Intraneuronal APP, Not Free Aβ Peptides in 3xTg-AD Mice: Implications for Tau versus Aβ-Mediated Alzheimer Neurodegeneration

Scientific Articles Accepted (Personal Checks, Too)

6/5/2015 Hagos Dimethyl fumarate attenuates cerebral edema formation by protecting the blood–brain barrier integrity.
5/29/2015 Yang Inhibition of 12/15-Lipoxygenase as Therapeutic Strategy to Treat Stroke
5/8/2015 Carlson Albumin induces excitatory synaptogenesis through astrocytic TGF-β/ALK5 signaling in a model of acquired epilepsy following blood–brain barrier dysfunction
5/1/2015  Fink, Mendelson  Therapeutic hypothermia after Out-of-Hospital Cardiac Arrest in Children
4/24/2015 Adams, Hagos

Special Topic Journal Club: "Transporters"

Quantitative Investigation of the Brian-to-Cerebrospinal Fluid Unbound Drug Concentration Ratio under Steady-State Conditions in Rats Using a Pharmacokinetic Model and Scaling Factors for Active Efflux Transporters.

Selective Increase of Two ABC Drug Efflux Transporters at the Blood-Spinal Cord Barrier Suggests Induced Pharmacoresistance in ALS

Inhibiting Drug Efflux Transporters Improves Efficacy of ALS Therapeutics

4/17/2015 Madha, Horvat

An overview of the diagnosis and treatment of TBI in blast injury.

Very Early Administration of Progesterone for Acute Traumatic Brain Injury.

4/9/2015 Kochanek Randomized Pilot Trial of Intensive Management of Blood Pressure of Volume Expansion in Subarachniod Hemorrhage (IMPROVES).
4/3/2015 Madha

Cytoskeletal protein α–II spectrin degradation in the brain of repeated blast exposed mice.

3/27/2015 Garman

Special Topic Journal Club: “Neuronal death or dark neuron artifact, which is it?” 

The Fate of Nissi-stained Dark Neurons Following Traumatic Brain Injury in Rats: Difference Between Neocortex and Hippocampus Regarding Survival Rate.

Pharmacologic Analysis of the Mechanism of Dark Neuron Production in Cerebral Cortex.

3/20/2015 Jackson, Jha

Special Topic Journal Club: "Cell Signaling Advances in Hypothermia"

RBM3 Mediates Structural Plasticity and Protective Effects of Cooling in Neurogeneration.

Cold-Inducibble RNA-Binding Protein (CIRP) Triggers Inflammatory Responses in Hemorrhagic Shock and Sepsis.

3/6/2015  Fidan Clinical Correlates in an Experimental Model of Repetitive Mild Traumatic Injury
2/27/2015 Dezfulian, Elmer

Special Topic Journal Club: "Post-Resuscitation Neuroprotective Therapies after Cardiac Arrest"

Remote Ischemic Pre- and Postconditioning Improve Postresuscitation Myocardial and Cerebral Function in a Rat Model of Cardiac Arrest and Resuscitation.

Cognitive Function in Survivors of Out-of-Hospital Cardiac Arrest After Target Temperature Management at 33ºC Versus 36ºC.

2/20/2015 Brockman, Adams

The Glasgow Coma Scale at 40 Years: Standing the Test of Time

Neuroprotective Effect of Ceftriaxone in a Rat model of Traumatic Brain Injury

2/10/2015 Carlson, Clark

Special Topic Journal Club: "Emphatic for the Glymphatic System"

Biomarkers of Traumatic Injury are Transported from Brain via the Glymphatic System

Impaired Glymphatic Perfusion after Strokes Revealed by Contrast-Enhanced MRI

2/6/2015 Simon, Li

Impairment of Glymphatic Pathway Function Promotes Tau Pathology after Traumatic Brain Injury

Evolution of Neuronal and Astroglial Disruption in the Peri-Contusional Cortex of Mice Revealed By in Vivo Two-Photon Imaging

1/30/2015 Bondi, Failla

Protein Carbonylation after Traumatic Brain Injury: Cell Specificity Regional Susceptibility, and Gender Differences

Enhanced Attention Capture by Emotional Stimuli in Mild Traumatic Brain Injury

1/16/2015 Kochanek Chronic Neuropathologies of Single Repetitive TBI: Substrates of Dementia
1/8/2015 Jha AQP4 Tag Single Nucleotide Polymorphisms in Patients with Traumatic Brain Injury